Eugenia Wang (born February 26, 1945) is the Gheens Endowed Chair on Aging at the
University of Louisville School of Medicine. Her primary focus is researching the genetic aspect of
aging
Ageing ( BE) or aging ( AE) is the process of becoming older. The term refers mainly to humans, many other animals, and fungi, whereas for example, bacteria, perennial plants and some simple animals are potentially biologically immortal. In ...
in humans.
She was among the first researchers who discovered the parts of the
human genome that could either accelerate or slow the process of
apoptosis
Apoptosis (from grc, ἀπόπτωσις, apóptōsis, 'falling off') is a form of programmed cell death that occurs in multicellular organisms. Biochemical events lead to characteristic cell changes (morphology) and death. These changes incl ...
.
Early life
Wang was born in Nanking, China during the
Chinese Civil War. Due to her country's internal strife, she and her mother and three siblings were forced to evacuate to Hanyang then Guangzhou. When she was three, they moved to
Taipei, Taiwan. Eventually her father joined them and remained there until 1967.
Eugenia Wang became professor of anatomy at
McGill University in 1988, where she worked on the cell biology of aging at the Lady Davis Institute of the Montreal Jewish General Hospital.
Selected publications
*Bates, D. J., Li, N., Liang, R., Sarojini, H., An, J., Masternak, M. M., Bartke, A., and Wang, E
MicroRNA regulation in Ames dwarf mouse liver is linked to delayed ageing. Aging Cell 9(1):1 - 18. (2010). ; NIHMSID: 158218.
*Khanna, A., Muthusamy, S., Liang, R., Sarojini, H., and Wang, E
Gain of survival signaling by down-regulation of three key miRNAs in brain of calorie-restricted mice Aging 3(3): 223 - 236 (2011). .
*Li, N., Bates, D. J., An, J., and Wang, E.
Up-regulation of key microRNAs and the inverse down-regulation of their potential target genes of oxidative phosphorylation during aging in mouse brains. Neurobiology of Aging 32: 944–955 (2011). .
*Liang, R., Khanna, A., Muthusamy, S., Li, N., Sarojini, H., Kopchick, J., Masternak, M.M., Bartke, A., and Wang, E.
Posttranscriptional regulation of IGF1R by key microRNAs in longlived mutant mice. Aging Cell. 10(6): 1080-1088 (2011). .
*Liang, R. and Wang E
Full-length 3' Un-Translated Region reporter construction with recombineering. Analytical Biochemistry. 424: 162-167 (2012)
References
External links
Papersat
PubMed
{{DEFAULTSORT:Wang, Eugenia
1945 births
Living people
University of Louisville faculty
American geneticists
Biologists from Kentucky
American women biologists
American women academics
21st-century American women