Etalocib is a drug candidate that was under development for the treatment of various types of cancer. It acts as a

leukotriene B4 receptor The leukotriene B4 receptors (BLTRs) include the following two receptors: * Leukotriene B4 receptor 1 (BLTR1) * Leukotriene B4 receptor 2 (BLTR2) See also * Eicosanoid receptor * Leukotriene receptor The leukotriene (LT) receptors are G protein ...

antagonist An antagonist is a character in a story who is presented as the chief foe of the protagonist. Etymology The English word antagonist comes from the Greek ἀνταγωνιστής – ''antagonistēs'', "opponent, competitor, villain, enemy, riv ...

and a PPARγ agonist. Clinical trials were conducted measuring efficacy for treatment of

non-small cell lung cancer Non-small-cell lung cancer (NSCLC) is any type of epithelial lung cancer other than small-cell lung carcinoma (SCLC). NSCLC accounts for about 85% of all lung cancers. As a class, NSCLCs are relatively insensitive to chemotherapy, compared to sm ...

and

pancreatic cancer Pancreatic cancer arises when cell (biology), cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a Neoplasm, mass. These cancerous cells have the malignant, ability to invade other parts of t ...

and the inflammatory conditions

asthma Asthma is a long-term inflammatory disease of the airways of the lungs. It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. Symptoms include episodes of wheezing, cou ...

psoriasis Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by raised areas of abnormal skin. These areas are red, pink, or purple, dry, itchy, and scaly. Psoriasis varies in severity from small, localized patches to complete ...

, and

ulcerative colitis Ulcerative colitis (UC) is a long-term condition that results in inflammation and ulcers of the colon and rectum. The primary symptoms of active disease are abdominal pain and diarrhea mixed with blood (hematochezia). Weight loss, fever, and a ...

, but were suspended due to lack of efficacy.

References

Leukotriene antagonists Salicylic acids Phenol ethers Fluoroarenes Abandoned drugs Biphenyls {{antineoplastic-drug-stub