Ernst Schulze (chemist)
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Ernst Schulze (; 31 July 1840,
Bovenden Bovenden is a municipality in the Göttingen (district), district of Göttingen, in Lower Saxony, Germany. In 2020 the population in the eight villages belonging to the municipality was 13,891. Geography Bovenden is situated on the river Leine, ...
near
Göttingen Göttingen (, , ; nds, Chöttingen) is a university city in Lower Saxony, central Germany, the capital of the eponymous district. The River Leine runs through it. At the end of 2019, the population was 118,911. General information The ori ...
– 15 June 1912,
Zürich , neighboring_municipalities = Adliswil, Dübendorf, Fällanden, Kilchberg, Maur, Oberengstringen, Opfikon, Regensdorf, Rümlang, Schlieren, Stallikon, Uitikon, Urdorf, Wallisellen, Zollikon , twintowns = Kunming, San Francisco Zürich ...
) was a German
chemist A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a scientist trained in the study of chemistry. Chemists study the composition of matter and its properties. Chemists carefully describe t ...
who discovered a number of
amino acid Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although hundreds of amino acids exist in nature, by far the most important are the alpha-amino acids, which comprise proteins. Only 22 alpha a ...
s.


Biography

Schulze's grandfather was the philosopher and privy counsellor
Gottlob Ernst Schulze Gottlob Ernst Schulze (; 23 August 1761 – 14 January 1833) was a German philosopher, born in Heldrungen (modern-day Thuringia, Germany). He was the grandfather of the pioneering biochemist Ernst Schulze. Biography Schulze was a professor at ...
, and his father held public office in the town where he was born: Bovenden near
Göttingen Göttingen (, , ; nds, Chöttingen) is a university city in Lower Saxony, central Germany, the capital of the eponymous district. The River Leine runs through it. At the end of 2019, the population was 118,911. General information The ori ...
. After completing school, Schulze studied chemistry at the
University of Göttingen The University of Göttingen, officially the Georg August University of Göttingen, (german: Georg-August-Universität Göttingen, known informally as Georgia Augusta) is a public research university in the city of Göttingen, Germany. Founded ...
. Among his professors were Friedrich Wöhler and Heinrich Limpricht. He completed his final semester at
Heidelberg Heidelberg (; Palatine German language, Palatine German: ''Heidlberg'') is a city in the States of Germany, German state of Baden-Württemberg, situated on the river Neckar in south-west Germany. As of the 2016 census, its population was 159,914 ...
, where he completed his studies under
Robert Wilhelm Bunsen Robert Wilhelm Eberhard Bunsen (; 30 March 1811 – 16 August 1899) was a German chemist. He investigated emission spectra of heated elements, and discovered caesium (in 1860) and rubidium (in 1861) with the physicist Gustav Kirchhoff. The ...
. Schulze then traveled to
Jena Jena () is a German city and the second largest city in Thuringia. Together with the nearby cities of Erfurt and Weimar, it forms the central metropolitan area of Thuringia with approximately 500,000 inhabitants, while the city itself has a po ...
, where he completed his doctoral studies as the assistant to Karl Gotthelf Lehmann and later to his successor, Anton Geuther, receiving his doctorate in 1867. He started his scientific career in Jena, and then went on to the agricultural research station at Weende near Göttingen, working under
Wilhelm Henneberg Wilhelm Henneberg (10 September 1825 – 22 November 1890) was a German chemist and student of Justus von Liebig. Life He attended the Collegium Carolinum in Brunswick and studied at the University of Giessen with Justus von Liebig and at the ...
, until in 1871 he was offered a position to lead a similar research station in Darmstadt. One year later, Schulze was appointed as professor for agricultural chemistry at the new agriculture and forestry school of the
Zürich polytechnic (colloquially) , former_name = eidgenössische polytechnische Schule , image = ETHZ.JPG , image_size = , established = , type = Public , budget = CHF 1.896 billion (2021) , rector = Günther Dissertori , president = Joël Mesot , a ...
, where his future father-in-law Adolf Kraemer had already been appointed as one of the first leaders. During his four decades at Zürich, Schulze concentrated on a variety of phytochemical studies, in the course of which he and his doctoral students discovered the
amino acid Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although hundreds of amino acids exist in nature, by far the most important are the alpha-amino acids, which comprise proteins. Only 22 alpha a ...
s
Glutamine Glutamine (symbol Gln or Q) is an α-amino acid that is used in the biosynthesis of proteins. Its side chain is similar to that of glutamic acid, except the carboxylic acid group is replaced by an amide. It is classified as a charge-neutral ...
, Phenylalanine and Arginine, among many other
organic compounds In chemistry, organic compounds are generally any chemical compounds that contain carbon-hydrogen or carbon-carbon bonds. Due to carbon's ability to catenate (form chains with other carbon atoms), millions of organic compounds are known. The s ...
. Schulze also laid emphasis on researching the importance of the amino acids
Asparagine Asparagine (symbol Asn or N) is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH form under biological conditions), an α-carboxylic acid group (which is in the depro ...
and
Glutamine Glutamine (symbol Gln or Q) is an α-amino acid that is used in the biosynthesis of proteins. Its side chain is similar to that of glutamic acid, except the carboxylic acid group is replaced by an amide. It is classified as a charge-neutral ...
in the protein metabolism of plants. He also pioneered the investigation of plant lecithin,
cholesterol Cholesterol is any of a class of certain organic molecules called lipids. It is a sterol (or modified steroid), a type of lipid. Cholesterol is biosynthesized by all animal cells and is an essential structural component of animal cell mem ...
and
phytosterols Phytosterols are phytosteroids, similar to cholesterol, that serve as structural components of biological membranes of plants. They encompass plant sterols and stanols. More than 250 sterols and related compounds have been identified. Free phytos ...
. At the end of his time in Zürich, Schulze researched the role of carbohydrates in plant cell membranes. This systematic research into plant chemistry made Schulze one of the pioneers of the new science of
biochemistry Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and ...
, at the time still called "physiological chemistry". In the middle of the 1880s, Schulze was awarded the Liebig-Medal in silver, and in 1907 he won a prize from the Royal Society of Sciences in Göttingen. In 1910, in recognition of his life's work, the
University of Heidelberg } Heidelberg University, officially the Ruprecht Karl University of Heidelberg, (german: Ruprecht-Karls-Universität Heidelberg; la, Universitas Ruperto Carola Heidelbergensis) is a public research university in Heidelberg, Baden-Württemberg, ...
awarded him an honorary medical doctorate.


Publications

* With Ernst Steiger: ''Ueber das Arginin.'' In: ''
Zeitschrift für Physiologische Chemie ''Biological Chemistry'' is a peer-reviewed scientific journal focusing on biological chemistry. The journal is published by Walter de Gruyter and the current editor-in-chief is Bernhard Brüne. History The journal was established by Felix Ho ...
.'' 11, 1887, p. 43
online
.


References

* ''Ernst Schulze.'' Obituary In ''Schweizerische Bauzeitung.'' 59/60, 1912
online
, PDF; 837 kB). * Ernst Winterstein: ''Ernst Schulze.'' In: ''Verhandlungen der Schweizerischen Naturforschenden Gesellschaft.'' Vol. 95, 1912. * Ernst Winterstein: ''Zur Erinnerung an Ernst Schulze.'' In: '' Hoppe-Seyler’s Zeitschrift für physiologische Chemie.'' Vol. 79, No. 6, 1912, , pp. 353–358. * Paul Walden: ''Geschichte der organischen Chemie seit 1880.'' 1941, pp. 612–631. * Frank Apel
''Biographie von Ernst Schulze.''
Hamburg, July 2015 (PDF; 902 kB)


External links


Ernst Schulze
at academictree.org {{DEFAULTSORT:Schulze, Ernst 19th-century chemists 1840 births 1912 deaths ETH Zurich faculty German biochemists 19th-century German scientists