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Ernest Edward Irons (February 17, 1877 – January 18, 1959) was an American physician who led several prominent medical organizations. Working as an intern under physician
James B. Herrick James Bryan Herrick (11 August 1861 in Oak Park, Illinois – 7 March 1954 in Chicago, Illinois) was an Americans, American physician and professor of medicine who practiced and taught in Chicago. He is credited with the description of sickl ...
, he identified abnormalities on a blood smear that resulted in the first published report of
sickle cell disease Sickle cell disease (SCD) is a group of blood disorders typically inherited from a person's parents. The most common type is known as sickle cell anaemia. It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blo ...
. Irons was later dean of
Rush Medical College Rush Medical College is the medical school of Rush University, located in the Illinois Medical District, about 3 km (2 miles) west of the Loop in Chicago. Offering a full-time Doctor of Medicine program, the school was chartered in 1837, and ...
, and he was president of the
American Medical Association The American Medical Association (AMA) is a professional association and lobbying group of physicians and medical students. Founded in 1847, it is headquartered in Chicago, Illinois. Membership was approximately 240,000 in 2016. The AMA's state ...
(AMA), the
American College of Physicians The American College of Physicians (ACP) is a national organization of internists, who specialize in the diagnosis, treatment, and care of adults.Sokanu "What is an Internist?" Retrieved October 20, 2014 With 161,000 members, ACP is the largest ...
and the American Association for the Study and Control of Rheumatic Diseases. Late in his life, he spent several years as the board president for the
Chicago Municipal Tuberculosis Sanitarium The Chicago Municipal Tuberculosis Sanitarium was located in Chicago, Illinois, USA. Founded in 1915, it was a municipal organization which included a sanatorium, dispensaries, and other auxiliary agencies essential in the control of tuberculosis ...
.


Early life

Irons was born on a farm in the area of
Council Bluffs, Iowa Council Bluffs is a city in and the county seat of Pottawattamie County, Iowa, Pottawattamie County, Iowa, United States. The city is the most populous in Southwest Iowa, and is the third largest and a primary city of the Omaha–Council Bluffs ...
, to Edward Irons and Mary J. Sharp Irons. In 1894, a young Irons was the founding president of the Iowa Ornithologists' Association. He remained involved with the group when he went to college at the
University of Chicago The University of Chicago (UChicago, Chicago, U of C, or UChi) is a private research university in Chicago, Illinois. Its main campus is located in Chicago's Hyde Park neighborhood. The University of Chicago is consistently ranked among the b ...
. He earned a medical degree from
Rush Medical College Rush Medical College is the medical school of Rush University, located in the Illinois Medical District, about 3 km (2 miles) west of the Loop in Chicago. Offering a full-time Doctor of Medicine program, the school was chartered in 1837, and ...
in 1903.


Career


Description of sickle cell disease

As a 27-year-old medical intern, Irons was working at Presbyterian Hospital in Chicago with
James B. Herrick James Bryan Herrick (11 August 1861 in Oak Park, Illinois – 7 March 1954 in Chicago, Illinois) was an Americans, American physician and professor of medicine who practiced and taught in Chicago. He is credited with the description of sickl ...
, who ran a
hematology Hematology ( always spelled haematology in British English) is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to blood. It involves treating diseases that affect the produc ...
clinic. Irons evaluated Walter Clement Noel, who had immigrated to Chicago from Grenada to enter dental school. Noel was experiencing weakness, shortness of breath and a painful sore on his ankle. Because of the Noel's country of origin and his symptoms, Irons and Herrick thought that the man had
malaria Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. S ...
. Irons took a blood sample from the patient and examined it under a microscope, expecting to confirm the malaria diagnosis. Instead, Irons noted elongated, sickle-shaped red blood cells on the slide. Irons alerted Herrick, and they attempted to come up with a
differential diagnosis In healthcare, a differential diagnosis (abbreviated DDx) is a method of analysis of a patient's history and physical examination to arrive at the correct diagnosis. It involves distinguishing a particular disease or condition from others that p ...
for the man's symptoms and blood results. The pair followed Noel for more than two years but ultimately lost track of him without establishing a diagnosis. After publishing reports of the man's illness in 1910, Herrick was credited with the first report of
sickle cell disease Sickle cell disease (SCD) is a group of blood disorders typically inherited from a person's parents. The most common type is known as sickle cell anaemia. It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blo ...
. After Noel completed dental school in Chicago, he returned to Grenada to open a dental clinic. He died of
pneumonia Pneumonia is an inflammatory condition of the lung primarily affecting the small air sacs known as alveoli. Symptoms typically include some combination of productive or dry cough, chest pain, fever, and difficulty breathing. The severity ...
a few years later.


Postgraduate training and medical practice

Irons pursued postgraduate studies in Vienna in 1909 and 1910. He studied
bacteriology Bacteriology is the branch and specialty of biology that studies the morphology, ecology, genetics and biochemistry of bacteria as well as many other aspects related to them. This subdivision of microbiology involves the identification, classificat ...
at the University of Chicago until 1912, graduating with a Ph.D. By the mid-1910s, Irons was on the executive committee of the Chicago Society of Internal Medicine. During
World War I World War I (28 July 1914 11 November 1918), often abbreviated as WWI, was one of the deadliest global conflicts in history. Belligerents included much of Europe, the Russian Empire, the United States, and the Ottoman Empire, with fightin ...
, he was a lieutenant colonel in the
U.S. Army Medical Corps The Medical Corps (MC) of the U.S. Army is a staff corps (non-combat specialty branch) of the U.S. Army Medical Department (AMEDD) consisting of commissioned medical officers – physicians with either an M.D. or a D.O. degree, at least one ye ...
and was placed in charge of the hospital at
Camp Custer Fort Custer Training Center, often known simply as Fort Custer, is a federally owned and state-operated Michigan Army National Guard training facility, but is also used by other branches of the armed forces and armed forces from Illinois, Indiana ...
. At a conference of the American Hospital Association in 1919, Irons presented a paper on the elimination of waste in hospital food service operations. In the same year, Irons explained to ''
The Literary Digest ''The Literary Digest'' was an influential American general interest weekly magazine published by Funk & Wagnalls. Founded by Isaac Kaufmann Funk in 1890, it eventually merged with two similar weekly magazines, ''Public Opinion'' and '' Current O ...
'' that Army hospitals were teaching technical skills to wounded soldiers. Irons said that even after wounds healed, a soldier remained stiff and that learning technical skills helped to rebuild his strength during the recovery process. He was dean of Rush Medical College from 1923 to 1936. Irons was named president of the board of directors of the
Chicago Municipal Tuberculosis Sanitarium The Chicago Municipal Tuberculosis Sanitarium was located in Chicago, Illinois, USA. Founded in 1915, it was a municipal organization which included a sanatorium, dispensaries, and other auxiliary agencies essential in the control of tuberculosis ...
(MTS) in 1948. The ''
Chicago Tribune The ''Chicago Tribune'' is a daily newspaper based in Chicago, Illinois, United States, owned by Tribune Publishing. Founded in 1847, and formerly self-styled as the "World's Greatest Newspaper" (a slogan for which WGN radio and television ar ...
'' credited Irons with greatly improving the services, outcomes and morale at the MTS, noting that the mortality rate fell and that the center's waiting list was able to be eliminated.


Service to national organizations

In the early 1920s, Irons was chairman of the
Nu Sigma Nu Nu Sigma Nu () was an international professional fraternity for medicine, now existing as a handful of stable remaining chapters. It was founded on 2 March 1882 by five medical students at the University of Michigan, who identified as their immed ...
national physician fraternity. He also served as president of the Institute of Medicine of Chicago. In 1934–1935, he was the founding president of the American Association for the Study and Control of Rheumatic Diseases, which was later known as the American Rheumatism Association and the
American College of Rheumatology The American College of Rheumatology (ACR; until 1985 called American Rheumatism Association) is an organization of and for physicians, health professionals, and scientists that advances rheumatology through programs of education, research, advocacy ...
. Irons was the president of the
American College of Physicians The American College of Physicians (ACP) is a national organization of internists, who specialize in the diagnosis, treatment, and care of adults.Sokanu "What is an Internist?" Retrieved October 20, 2014 With 161,000 members, ACP is the largest ...
from 1944 to 1946. He was the 1949–1950 president of the AMA. Irons and the AMA strongly opposed President Truman's proposal for a national health plan, referring to it as socialized medicine and drawing parallels to
Communism Communism (from Latin la, communis, lit=common, universal, label=none) is a far-left sociopolitical, philosophical, and economic ideology and current within the socialist movement whose goal is the establishment of a communist society, a s ...
. Even at his inaugural address as AMA president, Irons focused on the topic. "Nationalized medicine will be followed by nationalized industry. Industrialists see the threat to free enterprise and progress," he said. He later voiced his opposition to federal funding of both higher education and healthcare, saying, "Every subsidy carries with it the threat of regulation, despite any disclaimer of previous intent." While Irons was president, the AMA spent $1 million to fight Truman's health plan proposal.


Personal

Irons was married to the former Gertrude Thompson from Ontario. They had two children, physician Edwin N. Irons and attorney Spencer E. Irons.


Later life

In the 1950s, Irons published a book, ''The Story of Rush Medical College'', and he started work on a history of Presbyterian-St. Luke's Hospital. In November 1958, Irons was assaulted and robbed outside of his home in Chicago. The robbers stole a dollar in change from him. Still recovering from spinal injuries sustained in the attack, Irons suffered a heart attack and died at Presbyterian Hospital in Chicago on January 18, 1959.


References

{{DEFAULTSORT:Irons, Ernest E. 1877 births 1959 deaths 20th-century American physicians American hospital administrators Presidents of the American Medical Association Rush Medical College alumni University of Chicago alumni People from Council Bluffs, Iowa