Epsilonpapillomavirus 1
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''Epsilonpapillomavirus'' is a genus of
viruses A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1 ...
, in the family ''
Papillomaviridae ''Papillomaviridae'' is a family of non- enveloped DNA viruses whose members are known as papillomaviruses. Several hundred species of papillomaviruses, traditionally referred to as "types", have been identified infecting all carefully inspected ...
''. Cattle serve as natural hosts and it is one of the
bovine papillomavirus Bovine papillomaviruses (BPV) are a paraphyletic group of DNA viruses of the subfamily ''Firstpapillomavirinae'' of ''Papillomaviridae'' that are common in cattle. All BPVs have a circular genome, circular double-stranded DNA genome. Infection c ...
es. There are two species in this genus. Diseases associated with this genus include: fibropapillomas and true epithelial papillomas of the skin.


Taxonomy

The following two species are assigned to the genus: * '' Epsilonpapillomavirus 1'' * '' Epsilonpapillomavirus 2''


Structure

Viruses in ''Epsilonpapillomavirus'' are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 60 nm. Genomes are circular, around 8kb in length. The genome codes for 6 proteins.


Life cycle

Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. Dna templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown. Bovine serve as the natural host. Transmission routes are contact.


References


External links


ICTV Report ''Papillomaviridae''


{{Taxonbar, from=Q18819934 Papillomavirus Virus genera