Epidermal nevus syndrome (also known as "Feuerstein and Mims syndrome",
and "Solomon's syndrome"
[Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. .]) is a
rare disease that was first described in 1968 and consists of extensive epidermal
nevi with abnormalities of the
central nervous system (CNS), skeleton, skin,
cardiovascular system
The blood circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the entire body of a human or other vertebrate. It includes the cardiovascular system, or vascular system, tha ...
,
genitourinary system
The genitourinary system, or urogenital system, are the organs of the reproductive system and the urinary system. These are grouped together because of their proximity to each other, their common embryological origin and the use of common pathwa ...
and eyes.
[James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. .] However, since the syndrome's first description, a broader concept for the "epidermal nevus" syndrome has been proposed, with at least six types being described:
[Happle, R. "Epidermal nevus syndrome." ''Semin Dermatol''. 1995;14:111.]
:*
Schimmelpenning syndrome
:*
Nevus comedonicus syndrome
:*
Pigmented hairy epidermal nevus syndrome
:*
Proteus syndrome
:*
CHILD syndrome
:*
Phakomatosis pigmentokeratotica
See also
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Epidermis
The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. The epidermis layer provides a barrier to infection from environmental pathogens and regulates the amount of water rele ...
*
List of cutaneous conditions
Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. The major function of this system is as a barrier against t ...
References
External links
Epidermal nevi, neoplasms, and cysts
Rare syndromes
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