The Enterobacteria greA leader is a putative attenuator element identified by

bioinformatics Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combi ...

within bacteria of the γ-proteobacterial

Enterobacteriales Enterobacterales is an order of Gram-negative bacteria, Gram-negative, non-spore forming, Facultative anaerobic organism, facultatively anaerobic, rod-shaped bacteria with the class Gammaproteobacteria. The type genus of this order is ''Enterob ...

order. It is located upstream of the ''rnk'' gene, encoding a transcription

elongation factor Elongation factors are a set of proteins that function at the ribosome, during protein synthesis, to facilitate translational elongation from the formation of the first to the last peptide bond of a growing polypeptide. Most common elongation ...

, and presents a Rho-independent terminator at the 3' end. This

RNA Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation and expression of genes. RNA and deoxyribonucleic acid ( DNA) are nucleic acids. Along with lipids, proteins, and carbohydra ...

is presumed to operate as a non-coding leader, which regulatory mechanism remains to be elucidated. The short abortive form of the greA transcript may also play a role as an independent sRNA: Potrykus ''et al.'' have shown that its overexpression leads to the repression of several genes. The motif might be related to other rnk leaders such as the

Pseudomonas rnk leader The ''Pseudomonas'' rnk leader is a putative attenuator element identified by bioinformatics within bacteria of the γ-proteobacterial ''Pseudomonas'' genus. It is located upstream of the ''rnk'' gene, encoding a nucleoside diphosphate kinase reg ...

and the

Enterobacteria rnk leader The Enterobacteria rnk leader is a putative attenuator element identified by bioinformatics within bacteria of the γ-proteobacterial Enterobacteriales order. It is located upstream of the ''rnk'' gene, encoding a nucleoside diphosphate kinase regu ...

References

External links

*{{Rfam, id=RF01769, name=Enterobacteria greA leader Cis-regulatory RNA elements

See also

References

External links