Ent-kaurenoic acid oxidase () is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
with
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature.
A semisystematic name or semitrivial ...
''ent-kaur-16-en-19-oate,NADPH:oxygen oxidoreductase (hydroxylating)''.
This enzyme
catalyses the following
chemical reaction
A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...
: ent-kaur-16-en-19-oate + 3 NADPH + 3 H
+ + 3 O
2 gibberellin A12 + 3 NADP
+ + 4 H
2O (overall reaction)
:(1a) ent-kaur-16-en-19-oate + NADPH + H
+ + O
2 ent-7alpha-hydroxykaur-16-en-19-oate + NADP
+ + H
2O
:(1b) ent-7alpha-hydroxykaur-16-en-19-oate + NADPH + H
+ + O
2 gibberellin A12 aldehyde + NADP
+ + 2 H
2O
:(1c) gibberellin A12 aldehyde + NADPH + H
+ + O
2 gibberellin A12 + NADP
+ + H
2O
Ent-kaurenoic acid oxidase requires
cytochrome P450
Cytochromes P450 (CYPs) are a Protein superfamily, superfamily of enzymes containing heme as a cofactor (biochemistry), cofactor that functions as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are ...
.
References
External links
*
EC 1.14.13
{{Enzyme-stub