enzymology Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...

, an enoyl- cyl-carrier-proteinreductase (NADPH, B-specific) () is an enzyme that

catalyzes Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recyc ...

the chemical reaction :acyl- cyl-carrier-protein+ NADP⁺

\rightleftharpoons

trans-2,3-dehydroacyl- cyl-carrier-protein+ NADPH + H⁺ Thus, the two substrates of this enzyme are acyl-[acyl-carrier-protein">cyl-carrier-protein.html" ;"title="acyl- acyl- NADP⁺, whereas its 3 product (chemistry)">products are trans-2,3-dehydroacyl-[acyl-carrier-protein">cyl-carrier-proteinand nicotinamide adenine dinucleotide phosphate">NADP⁺, whereas its 3 product (chemistry)">products are trans-2,3-dehydroacyl-[acyl-carrier-protein], nicotinamide adenine dinucleotide phosphate, NADPH, and hydrogen ion, H⁺. This enzyme belongs to the family of oxidoreductases, to be specific, those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is acyl- cyl-carrier-proteinNADP+ oxidoreductase (B-specific). Other names in common use include acyl-ACP dehydrogenase, reductase, enoyl-

cyl carrier protein Cyl or CyL or CYL may refer to: * Cylindrospermopsin, a cyanotoxin produced by a variety of freshwater cyanobacteria * Spanish initialism for Castile and León, an autonomous community of Spain * an abbreviation used in eyeglass prescription Peo ...

(reduced nicotinamide, adenine dinucleotide phosphate), NADPH 2-enoyl Co A reductase, enoyl acyl-carrier-protein reductase, enoyl-ACP reductase, and enoyl- cyl-carrier-proteinreductase (NADPH, B-specific). This enzyme participates in fatty acid biosynthesis.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and .

References

* * * EC 1.3.1 NADPH-dependent enzymes Enzymes of known structure {{1.3-enzyme-stub