Elsie Sunderland
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Elsie M. Sunderland is a Canadian toxicologist and environmental scientist and the Gordon McKay Professor of Environmental Chemistry at
Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...
. She studies processes through which human activities increase and modify pollutants in natural ecosystems and living systems.


Research

Sunderland's research attempts to trace how the introduction of synthetic chemical compounds into the natural environment affects the global environment and food supplies of animals and people. Sunderland refers to the accelerating use of anthropogenic chemicals as civilization’s "global chemical experiment” that is affecting all continents and life on Earth. Her research seeks to track and quantify where these compounds go in the environment, and how they make their way into the tissues of wildlife and humans.


The Global Chemical Experiment

Sunderland and her research group at Harvard seek to model and quantify how human actions affect natural habitats and human food supplies, such as fish. The group develops mathematical models and conducts laboratory measurements of physical samples collected from ecosystems in order to develop mechanistic understanding that can inform policy and the public. These efforts seek to quantify and understand the “fate and transport” of natural and synthetic compounds. Sunderland's research seeks to trace the impact of introducing novel exogenous compounds on natural ecosystems. These compounds are more and more prevalent in natural habitats, largely as a consequence of the fact that modern industry relies on a growing range of chemical compounds, including heavy metals such as lead (Pb), copper (Cu), zinc (Zn). Further, chemical companies such as Dow and DuPont have created almost 100,000 synthetic organic chemicals. While these chemicals have enabled the
Green Revolution The Green Revolution, also known as the Third Agricultural Revolution, was a period of technology transfer initiatives that saw greatly increased crop yields and agricultural production. These changes in agriculture began in developed countrie ...
and
smart materials Smart materials, also called intelligent or responsive materials, are designed materials that have one or more properties that can be significantly changed in a controlled fashion by external stimuli, such as stress, moisture, electric or magnetic ...
, they also combine elements from across the periodic table into new materials that were not present throughout most of Earth’s history during which natural organisms evolved. Modern science has limited understanding of how these new compounds behave once released into the environment. Many of these synthetic chemicals persist and do not break down in the natural environment. As described in Sunderland’s tenure talk at Harvard, the group has explored several classes of contaminants with different chemical properties, including Mercury, PFAS, and PCBs.


Global Mercury Cycle

Sunderland’s early work focused on
methylmercury Methylmercury (sometimes methyl mercury) is an organometallic cation with the formula . It is the simplest organomercury compound. Methylmercury is extremely toxic, and its derivatives are the major source of organic mercury for humans. It is a ...
in Passamaquoddy Bay on the edge of the North Atlantic. Over time, this interest expanded to the global processes that transport mercury through the world’s oceans, ecosystems, and human food supply.
Mercury Mercury commonly refers to: * Mercury (planet), the nearest planet to the Sun * Mercury (element), a metallic chemical element with the symbol Hg * Mercury (mythology), a Roman god Mercury or The Mercury may also refer to: Companies * Merc ...
is a naturally occurring element that is
toxic Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism. Toxicity can refer to the effect on a whole organism, such as an animal, bacterium, or plant, as well as the effect on a subst ...
to
nerve cells A neuron, neurone, or nerve cell is an electrically excitable cell that communicates with other cells via specialized connections called synapses. The neuron is the main component of nervous tissue in all animals except sponges and placozoa. No ...
and can
bioaccumulate Bioaccumulation is the gradual accumulation of substances, such as pesticides or other chemicals, in an organism. Bioaccumulation occurs when an organism absorbs a substance at a rate faster than that at which the substance is lost or eliminated ...
when
methylated In the chemical sciences, methylation denotes the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group. Methylation is a form of alkylation, with a methyl group replacing a hydrogen atom. These t ...
. By organizing the central principles of the global mercury cycle, Sunderland’s group has led development of models that quantify the impacts of human activities on the fate and transport of mercury. These models have enabled deeper understanding of how climate change is affecting mercury levels in fish that people eat. While US environmental regulations caused coal fired power plants to reduce their emissions of mercury, the group’s models have found that in some cases the effects of climate change on mercury levels have outpaced those reductions leading to more mercury in fish. Related work has assessed how hydroelectric developments in NewFoundland increasing risk of methylmercury poisoning in indigenous peoples near the Arctic Development of hydroelectric dams and as well as permafrost thaw from global warming could increase the impact of mercury on human populations in the arctic.


Fluorinated Compounds

Expanding beyond mercury, Sunderland’s group has sought to understand how people are exposed to poly- and perfluoroalkyl substances (
PFAS Per- and polyfluoroalkyl substances (PFASs) are synthetic organofluorine chemical compounds that have multiple fluorine atoms attached to an alkyl chain. An early definition, from 2011, required that they contain at least one perfluoroalkyl mo ...
) and to develop quantitative tools tracing PFAS exposures back to their sources. This thread of research includes work on
Cape Cod Cape Cod is a peninsula extending into the Atlantic Ocean from the southeastern corner of mainland Massachusetts, in the northeastern United States. Its historic, maritime character and ample beaches attract heavy tourism during the summer mont ...
, where a team of researchers including Sunderland have been studying drinking water. That work led to a widely read scientific paper titled “Detection of Poly- and Perfluoroalkyl Substances (PFASs) in U.S. Drinking Water Linked to Industrial Sites, Military Fire Training Areas, and Wastewater Treatment Plants” with several co-authors including Arlene Blum and Philippe Grandjean. More recently, PFAS have appeared in bottled drinking water, and Sunderland has been interviewed as an expert on the matter.


Polychlorinated Biphenyls (PCBs)

The impact of PCBs on living organisms has been studied extensively, and the Sunderland group has extended this work by developing global models of how these long-lived persistent pollutants move through the world.


Awards

In 2019, the Web of Science recognized Sunderland as a Highly Cited Researcher with multiple highly cited papers in top 1% of the field. In 2012, the Star Family gave awards to Sunderland recognizing her excellent and promising scientific research. Sunderland was recognized for her service as a peer reviewer by the journal Biogeochemistry and the Editorial Board of Estuaries and Coasts. While working at the
US EPA The Environmental Protection Agency (EPA) is an independent executive agency of the United States federal government tasked with environmental protection matters. President Richard Nixon proposed the establishment of EPA on July 9, 1970; it be ...
, the agency recognized Sunderland with the U.S. EPA Level II Scientific & Technological Achievement (STAA) Award (2010), U.S. EPA Level I (highest level) Scientific & Technological Achievement (STAA) Award (2008), and U.S. EPA National Honor Award, Gold Medal for Exceptional Service (2005).
SFU Simon Fraser University (SFU) is a public research university in British Columbia, Canada, with three campuses, all in Greater Vancouver: Burnaby (main campus), Surrey, and Vancouver. The main Burnaby campus on Burnaby Mountain, located from ...
awarded the Dean’s Convocation Medal for best graduate thesis to Sunderland.


References


External links

* {{DEFAULTSORT:Sunderland, Elsie Harvard University faculty Living people Year of birth missing (living people) Women chemists Toxicologists Simon Fraser University alumni McGill University alumni