Elizabeth Wayne (biomedical Engineer)
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Elizabeth Wayne is an Assistant Professor of Biomedical Engineering and Chemical Engineering at
Carnegie Mellon University Carnegie Mellon University (CMU) is a private research university in Pittsburgh, Pennsylvania. One of its predecessors was established in 1900 by Andrew Carnegie as the Carnegie Technical Schools; it became the Carnegie Institute of Technology ...
and former Postdoc at the Center for Nanotechnology in Drug Delivery at the
University of North Carolina at Chapel Hill A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States ...
. Wayne was a 2017 TED fellow and is a member of a number of professional societies, including the National Society of Black Physicists.


Early life and education

Born and raised in Mississippi, Wayne attended the
Mississippi School for Mathematics and Science The Mississippi School for Mathematics and Science (MSMS) is Mississippi's only public residential high school for academically gifted students and is located in Columbus, Mississippi, United States on the campus of the Mississippi University for ...
in Columbus, MS before moving away to attend school at the University of Pennsylvania. Wayne earned an undergraduate degree in physics at the
University of Pennsylvania The University of Pennsylvania (also known as Penn or UPenn) is a private research university in Philadelphia. It is the fourth-oldest institution of higher education in the United States and is ranked among the highest-regarded universitie ...
in 2009. She later earned her PhD from
Cornell University Cornell University is a private statutory land-grant research university based in Ithaca, New York. It is a member of the Ivy League. Founded in 1865 by Ezra Cornell and Andrew Dickson White, Cornell was founded with the intention to teach an ...
, researching immune cell-mediated drug delivery. Wayne organised the 2013 Northeast Conference for Undergraduate Women in Physics, raising $60,000 for delegates to attend.


Research

Wayne joined the Center for Nanotechnology in Drug Delivery at the
University of North Carolina at Chapel Hill A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States ...
in 2015. Her research focuses on cancer treatment using cells to deliver proteins, genes and drugs. Beginning in Fall 2019, Dr. Elizabeth Wayne joined the faculty of
Carnegie Mellon University Carnegie Mellon University (CMU) is a private research university in Pittsburgh, Pennsylvania. One of its predecessors was established in 1900 by Andrew Carnegie as the Carnegie Technical Schools; it became the Carnegie Institute of Technology ...
as an assistant professor of Biomedical Engineering and Chemical Engineering. Her current research focuses on drug delivery for cancer treatment, specifically the use of
macrophages Macrophages (abbreviated as M φ, MΦ or MP) ( el, large eaters, from Greek ''μακρός'' (') = large, ''φαγεῖν'' (') = to eat) are a type of white blood cell of the immune system that engulfs and digests pathogens, such as cancer ce ...
to deliver therapeutic genes to solid tumors. Her research laboratory at Carnegie Mellon works to understand how macrophage activation can be used to interpret drug pharmacokinetics and pharmacodynamics during disease progression and tissue regeneration.


Awards

Wayne has won many awards and fellowships. At Cornell, she won the ''Robert Mozia Graduate Distinguished Service Award,'' the ''CMM Young Investigator Award,''the''Alice & Constance Cook Award,'' and the ''Cornell Women’s Day Leadership Award''. She was also awarded: the Howard Hughes Medical Institute Med-into-Grad Fellowship, funds from the NCI Physical Sciences in Oncology Network and the Sage and Provost Diversity Fellowship.


Public engagement

She co-hosts the podcast PhDivas, which discusses academia, culture, and social justice across the STEM/ humanities divide. She has been a chief organizer in the Conference for Undergraduate Women in Physics (CUWIP) at Cornell as well as a panelist and workshop leader at CUWIPs held at Yale and Harvard. In 2017 she was awarded a
TED fellowship TED Conferences, LLC (Technology, Entertainment, Design) is an American-Canadian non-profit media organization that posts international talks online for free distribution under the slogan "ideas worth spreading". TED was founded by Richard Sau ...
, which identifies her as "a visionary who collaborates across disciplines in an effort to create positive change around the world". She delivered a TED talk in April 2017 titled 'We can hack our immune cells to fight cance

which has had over one million views.


Publications

1. Wayne, EC, Chandrasekaran, S, Mitchell, MJ, Chan MF, Lee, RE, Schaffer, CB, & King, MR (2016). TRAIL-coated leukocytes that prevent the bloodborne metastasis of prostate cancer. Journal of Controlled Release
''Journal of Controlled Release : Official Journal of the Controlled Release Society'', ''223'', 215–223.
2. Mitchell MJ, Wayne EC, Rana K, Schaffer CB, King MR. (2014) TRAIL-Coated Leukocytes that Kill Cancer Cells in the Circulation
PNAS 111(3) 930–935
3. Rosenthal JA, Huang C-J, Doody AM, Leung T, Mineta K, Feng D, Wayne EC, Nozomi Nishimura, Cynthia Leifer, Matthew P. DeLisa, Susana Mendez, David Putnam. (2014) Mechanistic Insight into the TH1-Biased Immune Response to Recombinant Subunit Vaccines Delivered by Probiotic Bacteria-Derived Outer Membrane Vesicles
PLoS ONE 9(11): e112802.


References


External links

*
PBS NewsHour: Brief but Spectacular
{{DEFAULTSORT:Wayne, Elizabeth C. Living people American biomedical engineers American women physicists Women biophysicists 21st-century American physicists Cornell University alumni University of Pennsylvania alumni Year of birth missing (living people) Members of the National Society of Black Physicists 21st-century American women scientists African-American physicists