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An elixir is a sweet liquid used for medical purposes, to be taken orally and intended to cure one's illness. When used as a pharmaceutical preparation, an elixir contains at least one active ingredient designed to be taken orally.


Etymology

The word was introduced in late Middle English, through Latin from the Arabic (), which in turn is the
Arabization Arabization or Arabisation ( ar, تعريب, ') describes both the process of growing Arab influence on non-Arab populations, causing a language shift by the latter's gradual adoption of the Arabic language and incorporation of Arab culture, aft ...
of the Ancient Greek () (from () ). For centuries, ''elixir'' primarily meant an ingredient used in alchemy, either referring to a liquid which purportedly converts lead to gold, or a substance or liquid which is believed to cure all ills and give eternal life.


Types


Non-medicated elixirs

These are used as
solvents A solvent (s) (from the Latin '' solvō'', "loosen, untie, solve") is a substance that dissolves a solute, resulting in a solution. A solvent is usually a liquid but can also be a solid, a gas, or a supercritical fluid. Water is a solvent for p ...
or vehicles for the preparation of medicated elixirs. Active ingredients are dissolved in a 15–⁠50% by volume solution of ethyl alcohol: *aromatic elixirs ( USP) *isoalcoholic elixirs ( NF) *compound
benzaldehyde Benzaldehyde (C6H5CHO) is an organic compound consisting of a benzene ring with a formyl substituent. It is the simplest aromatic aldehyde and one of the most industrially useful. It is a colorless liquid with a characteristic almond-like odor. ...
elixirs (NF)


Medicated elixirs

These include: *
antihistaminic Antihistamines are drugs which treat allergic rhinitis, common cold, influenza, and other allergies. Typically, people take antihistamines as an inexpensive, generic (not patented) drug that can be bought without a prescription and provides re ...
elixirs used against allergy, such as
chlorpheniramine maleate Chlorphenamine (CP, CPM), also known as chlorpheniramine, is an antihistamine used to treat the symptoms of allergic conditions such as allergic rhinitis (hay fever). It is taken by mouth. The medication takes effect within two hours and lasts ...
(USP) or diphenhydramine HCl *
sedative A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement. They are CNS depressants and interact with brain activity causing its deceleration. Various kinds of sedatives can be distinguished, but t ...
and
hypnotic Hypnotic (from Greek ''Hypnos'', sleep), or soporific drugs, commonly known as sleeping pills, are a class of (and umbrella term for) psychoactive drugs whose primary function is to induce sleep (or surgical anesthesiaWhen used in anesthesia ...
elixirs, the former to induce drowsiness, the latter to induce sleep *pediatric elixirs such as chloral hydrate * expectorant elixirs used to facilitate productive cough (i.e. cough with
sputum Sputum is mucus that is coughed up from the lower airways (the trachea and bronchi). In medicine, sputum samples are usually used for a naked eye examination, microbiological investigation of respiratory infections and cytological investigations ...
), such as
terpin hydrate Terpin, used as the hydrate (terpin·H2O), is an expectorant, used to loosen mucus in patients with bronchitis and related conditions. It is derived from sources such as turpentine, oregano, thyme, and eucalyptus. It was used in the United State ...


East Asian vitamin drinks

Daily non-alcoholic non-caffeinated 'vitamin drinks' have been popular in East Asia since the 1950s, with Oronamin from Otsuka Pharmaceutical perhaps the market leader. Packaged in brown light-proof bottles, these drinks have the reputation of being enjoyed by old men and other health-conscious individuals. Counterparts exist in South Korea and China. Western energy drinks typically have caffeine and are targeted at a younger demographic, with colorful labels and printed claims of increased athletic/daily performance.


Pseudomedicinal drinks

See Patent medicine.


Composition

An elixir is a hydro-
alcohol Alcohol most commonly refers to: * Alcohol (chemistry), an organic compound in which a hydroxyl group is bound to a carbon atom * Alcohol (drug), an intoxicant found in alcoholic drinks Alcohol may also refer to: Chemicals * Ethanol, one of sev ...
ic solution of at least one active ingredient. The alcohol is mainly used to: * Solubilize the active ingredient(s) and some excipients * Retard the crystallization of sugar * Preserve the finished product * Provide a sharpness to the taste * Aid in masking the unpleasant taste of the active ingredient(s) * Enhance the flavor. The lowest alcoholic quantity that will dissolve completely the active ingredient(s) and give a clear solution is generally chosen. High concentrations of alcohol give burning taste to the final product. An elixir may also contain the following excipients: *
Sugar Sugar is the generic name for sweet-tasting, soluble carbohydrates, many of which are used in food. Simple sugars, also called monosaccharides, include glucose, fructose, and galactose. Compound sugars, also called disaccharides or double ...
and/or
sugar substitute A sugar substitute is a food additive that provides a sweetness like that of sugar while containing significantly less food energy than sugar-based sweeteners, making it a zero-calorie () or low-calorie sweetener. Artificial sweeteners may be d ...
s like the sugar polyols glycerol and
sorbitol Sorbitol (), less commonly known as glucitol (), is a sugar alcohol with a sweet taste which the human body metabolizes slowly. It can be obtained by reduction of glucose, which changes the converted aldehyde group (−CHO) to a primary alcohol g ...
. * Preservatives like parabens and
benzoates Benzoates (salts of benzoic acid) can refer to: *Ammonium benzoate *Calcium benzoate *Magnesium benzoate *Potassium benzoate * Sodium benzoate Sodium benzoate is the sodium salt of benzoic acid, widely used as a food preservative (with an E num ...
and
antioxidant Antioxidants are compounds that inhibit oxidation, a chemical reaction that can produce free radicals. This can lead to polymerization and other chain reactions. They are frequently added to industrial products, such as fuels and lubricant ...
s like butylated hydroxytoluene (BHT) and sodium metabisulfite. * Buffering agents * Chelating agents like sodium ethylenediaminetetraacetic acid ( EDTA) * Flavoring agents and flavor enhancers * Coloring agents


Storage

Elixirs should only be stored in a tightly closed, light resistant container away from direct heat and sunlight.


See also

* Brompton cocktail * Concoction * Elixir of life * Internal alchemy * Energy drink *
Soft drink A soft drink (see § Terminology for other names) is a drink that usually contains water (often carbonated), a sweetener, and a natural and/or artificial flavoring. The sweetener may be a sugar, high-fructose corn syrup, fruit juice, a su ...
* Panacea (medicine), mythological remedy that would cure all diseases *
Suspension (chemistry) In chemistry, a suspension is a heterogeneous mixture of a fluid that contains solid particles sufficiently large for sedimentation. The particles may be visible to the naked eye, usually must be larger than one micrometer, and will eventually se ...
* Syrup *
Spagyric Paracelsianism (also Paracelsism; German: ') was an early modern medical movement based on the theories and therapies of Paracelsus. It developed in the second half of the 16th century, during the decades following Paracelsus' death in 1541, an ...
* Herbal tea * Tincture, in which alcohol is the major solvent and the ingredient is often highly concentrated. * Theriac


References

{{Authority control Drug delivery devices Dosage forms