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Elba E. Serrano is a neuroscientist and biophysicist who holds a position as a Regent's Professor of Biology at New Mexico State University. She is known for her contributions to research on the
nervous system of gastropods The nervous system of gastropods consists of a series of paired ganglia connected by major nerve cords, and a number of smaller branching nerves. It is sometimes called ganglionic. Description The brain of a gastropod consists of three pairs ...
,
inner ear The inner ear (internal ear, auris interna) is the innermost part of the vertebrate ear. In vertebrates, the inner ear is mainly responsible for sound detection and balance. In mammals, it consists of the bony labyrinth, a hollow cavity in the ...
development in
Xenopus ''Xenopus'' () (Gk., ξενος, ''xenos''=strange, πους, ''pous''=foot, commonly known as the clawed frog) is a genus of highly aquatic frogs native to sub-Saharan Africa. Twenty species are currently described within it. The two best-known ...
, neurobiology of glia, sensory signal transduction in
guard cell Guard cells are specialized plant cells in the epidermis of leaves, stems and other organs that are used to control gas exchange. They are produced in pairs with a gap between them that forms a stomatal pore. The stomatal pores are largest when ...
s, and for leadership of programs that recruit, train and retain underrepresented minorities in STEM. Her research considers the central role of
ion channel Ion channels are pore-forming membrane proteins that allow ions to pass through the channel pore. Their functions include establishing a resting membrane potential, shaping action potentials and other electrical signals by gating the flow of io ...
s in the reception and transduction of stimuli and integrates methods from genetics, physiology, and anatomy. In 2020 she was named as one of ''100 inspiring Hispanic/Latinx scientists in America ''


Early life and education

Serrano was born in Old San Juan. Her father was a sergeant in the
United States Army The United States Army (USA) is the land service branch of the United States Armed Forces. It is one of the eight U.S. uniformed services, and is designated as the Army of the United States in the U.S. Constitution.Article II, section 2, cla ...
and a military veteran, which meant that Serrano was raised in Central America, Asia and Europe. She attended almost ten different schools and eventually graduated from the
Nurnberg American High School Nürnberg American High School (NAHS) was a Department of Defense Dependents Schools (DoDDS) system school located near Nürnberg, Germany. One of DoDDS original five high schools in Germany, the school served the children of American militar ...
. She earned a bachelor's degree in physics at the
University of Rochester The University of Rochester (U of R, UR, or U of Rochester) is a private research university in Rochester, New York. The university grants undergraduate and graduate degrees, including doctoral and professional degrees. The University of Roc ...
, where she became interested in biophysics. Her undergraduate research was completed under the guidance of Edwin Carstensen, Professor of Electrical Engineering Whilst a physics student Serrano was one of two women out of eighty students. She moved to
Stanford University Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is consider ...
for her doctoral degree, where she earned a PhD in Biology specializing in neuroscience and biophysics under the supervision of Peter A. Getting in 1983. Her dissertation considered the movement of ions across the cell membrane of giant neurons. After earning her PhD she trained as a postdoctoral researcher with Bruce Ransom and
Robert Schimke Robert Tod Schimke (October 25, 1932 – September 6, 2014) was an American biochemist and cancer researcher. He was born in Spokane, Washington, the son of a dentist and a homemaker. Schimke obtained an undergraduate degree from Stanford Univers ...
at Stanford University studying the effects of antiepileptic drugs and antineoplastic drugs on primary neural and glial cultures. She then joined the laboratory of
Susumu Hagiwara Susumu Hagiwara ( ja, 萩原 生長; November 6, 1922 – April 1, 1989) was a Japanese-born American physician and neuroscientist. http://www.nasonline.org/publications/biographical-memoirs/memoir-pdfs/hagiwara-susumu.pdf Hagiwara was born and r ...
at
University of California, Los Angeles The University of California, Los Angeles (UCLA) is a public land-grant research university in Los Angeles, California. UCLA's academic roots were established in 1881 as a teachers college then known as the southern branch of the California St ...
Medical School. Here she became interested in sensory cells in plants and in the inner ear, in particular, the mechanosensory hair cells.


Career and research

Serrano joined New Mexico State University in 1992, where she established NMSU's first neuroscience research laboratory. Serrano was selected as a Regents Professor in 2009. Her research considers the ear, hearing and balance,as well as the role of
neuroglia Glia, also called glial cells (gliocytes) or neuroglia, are non-neuronal cells in the central nervous system (brain and spinal cord) and the peripheral nervous system that do not produce electrical impulses. They maintain homeostasis, form mye ...
in brain function. She has studied the transduction of light by plant
stomata In botany, a stoma (from Greek ''στόμα'', "mouth", plural "stomata"), also called a stomate (plural "stomates"), is a pore found in the epidermis of leaves, stems, and other organs, that controls the rate of gas exchange. The pore is bor ...
and the formation of sensory organs, and the ways sensory cells acquire their
phenotypes In genetics, the phenotype () is the set of observable characteristics or traits of an organism. The term covers the organism's morphology or physical form and structure, its developmental processes, its biochemical and physiological proper ...
. She has developed approaches to image neurons and inner ear sensory cells with the scanning electron microscopy and
transmission electron microscopy Transmission electron microscopy (TEM) is a microscopy technique in which a beam of electrons is transmitted through a specimen to form an image. The specimen is most often an ultrathin section less than 100 nm thick or a suspension on a g ...
and ''in vivo'', primarily using multi-photon microscopy., as well as using high throughput methods such as
RNA-Seq RNA-Seq (named as an abbreviation of RNA sequencing) is a sequencing technique which uses next-generation sequencing (NGS) to reveal the presence and quantity of RNA in a biological sample at a given moment, analyzing the continuously changing c ...
and microarrays to study genes expressed in the inner ear and cell cultures of neuroglia.


Awards and honors

Serrano is the recipient of numerous awards and honors. These include: election as a Fellow of the American Association for the Advancement of Science (2012); the
Society for the Advancement of Chicanos/Hispanics and Native Americans in Science The 'Society for Advancement of Chicanos/Hispanics and Native Americans in Science (SACNAS)'' is a society that aims to further the success of Chicano/Hispanic and Native American students in obtaining advanced degrees, careers, leadership positi ...
(SACNAS) Distinguished Mentor award (2015); the
Presidential Award for Excellence in Science, Mathematics, and Engineering Mentoring The Presidential Award for Excellence in Science, Mathematics and Engineering Mentoring (PAESMEM) is a Presidential award established by the United States White House in 1995. The program is administered by the National Science Foundation (NSF) on ...
(2018). Serrano also has been recognized as an
American Association for the Advancement of Science The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific respons ...
International Lecturer on Women in Science (2002) and was awarded a Ford Foundation Fellowship. She is the recipient of a 2021 US Fulbright Scholar Award for research in Portugal at the
University of Aveiro The University of Aveiro ( pt, Universidade de Aveiro) is a public university, in addition to providing polytechnic education, located in the Portuguese city of Aveiro. Founded in 1973, it has a student population of approximately 12,500, distri ...
.


Mentoring and advocacy

At New Mexico State University Serrano served as Principal Investigator of the institution's NIH Research Initiative for Scientific Enhancement (RISE) and as the co-originator of the NMSU NIH BP-ENDURE Building Research Achievement in Neuroscience (BRAiN) programs, which have supported hundreds of underrepresented minority students across the university to enter biomedical research careers. From 1992 to 2019 over one hundred and twenty students have earned degrees while completing mentored research in the Serrano laboratory, half of whom are women and over 60% are from underrepresented groups. In 2018, the
National Science Foundation The National Science Foundation (NSF) is an independent agency of the United States government that supports fundamental research and education in all the non-medical fields of science and engineering. Its medical counterpart is the National I ...
announced that it would establish the National Resource Hub for STEM Education at Hispanic-serving institution(HSI Resource Hub) at New Mexico State University. under Serrano's leadership. The Hub's mission is to increase the capacity of Hispanic-serving institutions to provide research and education activities that recruit, train, and retain students for the
STEM Stem or STEM may refer to: Plant structures * Plant stem, a plant's aboveground axis, made of vascular tissue, off which leaves and flowers hang * Stipe (botany), a stalk to support some other structure * Stipe (mycology), the stem of a mushro ...
workforce.


National service

Serrano has served on Francis Collins' Advisory Committee to the Director (ACD) of NIH
National Institutes of Health The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late ...
(2014-2018). She has co-Chaired the ACD Working Group on Diversity with
Hannah Valantine Dr. Hannah Valantine is the Chief Officer for Scientific Workforce Diversity at the United States National Institutes of Health. Biography Valantine was born in The Gambia and lived in Banjul as a child. When her father was selected as the G ...
and is part of the NIH
BRAIN Initiative The White House BRAIN Initiative (Brain Research through Advancing Innovative Neurotechnologies) is a collaborative, public-private research initiative announced by the Obama administration on April 2, 2013, with the goal of supporting the devel ...
Multi-Council Working Group. Serrano has worked on behalf of many scientific societies that promote research and student training including the Professional Development Committee for the Society for Neuroscience and the Steering Committee for the Annual Biomedical Research Conference for Minority Students.


References

{{DEFAULTSORT:Serrano, Elba Living people University of Rochester alumni Stanford University alumni New Mexico State University faculty Year of birth missing (living people) American women neuroscientists American neuroscientists American women academics American people of Puerto Rican descent