Elastosis perforans serpiginosa is a unique perforating
disorder
Disorder may refer to randomness, non-order, or no intelligible pattern.
Disorder may also refer to:
Healthcare
* Disorder (medicine), a functional abnormality or disturbance
* Mental disorder or psychological disorder, a psychological pattern a ...
characterized by transepidermal elimination of
elastic fiber
Elastic fibers (or yellow fibers) are an essential component of the extracellular matrix composed of bundles of proteins (elastin) which are produced by a number of different cell types including fibroblasts, endothelial, smooth muscle, and air ...
s and distinctive clinical
lesion
A lesion is any damage or abnormal change in the tissue of an organism, usually caused by disease or trauma. ''Lesion'' is derived from the Latin "injury". Lesions may occur in plants as well as animals.
Types
There is no designated classifi ...
s, which are
serpiginous
Serpiginous, first known to be used in the 15th century, is a term from Latin serpere to creep, usually referring to a creeping, snakelike or slowly progressive skin disease.
It is used to describe the rash in cutaneous larvae migrans, erythema an ...
in distribution and can be associated with specific diseases.
[Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). Page 1041. McGraw-Hill. .]
File:Histopathology of elastosis perforans serpiginosa.jpg, Histopathology of elastosis perforans serpiginosa: Degenerated elastic fibers and transepidermal perforating canals (arrow points at one of them)
File:Autosomal dominant - en.svg, This condition is inherited in an autosomal dominant
In genetics, dominance is the phenomenon of one variant (allele) of a gene on a chromosome masking or overriding the effect of a different variant of the same gene on the other copy of the chromosome. The first variant is termed dominant and t ...
manner.
See also
*
List of cutaneous conditions
Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. The major function of this system is as a barrier against t ...
*
Poikiloderma vasculare atrophicans
Poikiloderma vasculare atrophicans (PVA), is a cutaneous condition (skin disease) characterized by hypo- or hyperpigmentation (diminished or heightened skin pigmentation, respectively), telangiectasia and skin atrophy. Other names for the conditi ...
References
External links
Abnormalities of dermal fibrous and elastic tissue
{{Cutaneous-condition-stub