''Eimeria zuernii'' is a species of the parasite ''
Eimeria
''Eimeria'' is a genus of apicomplexan parasites that includes various species capable of causing the disease coccidiosis in animals such as cattle, poultry and smaller ruminants including sheep and goats. ''Eimeria'' species are considered to be ...
'' that causes diarrheic disease known as eimeriosis in
cattle
Cattle (''Bos taurus'') are large, domesticated, cloven-hooved, herbivores. They are a prominent modern member of the subfamily Bovinae and the most widespread species of the genus ''Bos''. Adult females are referred to as cows and adult mal ...
(''Bos taurus''), and mainly affects younger animals. The disease is also commonly referred to as
coccidiosis
Coccidiosis is a parasitic disease of the intestinal tract of animals caused by coccidian protozoa. The disease spreads from one animal to another by contact with infected feces or ingestion of infected tissue. Diarrhea, which may become bloody in ...
. The parasite can be found in cattle around the globe.
Description
''Eimeria zuernii'' is a very host specific parasite that only infects cattle.
[ Cattle gets infected by ingesting food, water or surfaces contaminated with infective (sporulated) oocysts (fecal-oral-route).
After the oocyst hatch in the gut of the animal it releases 8 zoites that undergo two asexual cycles (schizogony). The first cycle happens inside the lamina propria cells and produces many small schizonts. The second generation of schizonts target epithelial cells in the cecum and colon. The second generation of schizonts undergo a sexual cycle (gametogony) which is also the time when clinical signs of the disease can be observed. The release of new oocysts destroys mucosal cells which can lead to loss of serum and blood. This can be observed as bloody diarrhea. The time from ingestion of the parasite to the first signs of disease (prepatent period) is 12–14 days.]
Oocysts can be observed in a microscope as a colourless, single-layered wall with no micropyle with a size of 15–22 µm x 13–18 µm and having a subspherical, subovoid or elliptic shape.[
]
Diagnosis
The infection status of an animal is evaluated by examining the oocysts using different flotation methods, usually by counting the oocysts under a light microscope and identifying the species of the ''Eimeria
''Eimeria'' is a genus of apicomplexan parasites that includes various species capable of causing the disease coccidiosis in animals such as cattle, poultry and smaller ruminants including sheep and goats. ''Eimeria'' species are considered to be ...
'' based on morphology. When evaluating if the animal is having eimeriosis, due to infection with ''E. zuernii'' (eimeriosis) or other pathogenic ''Eimeria
''Eimeria'' is a genus of apicomplexan parasites that includes various species capable of causing the disease coccidiosis in animals such as cattle, poultry and smaller ruminants including sheep and goats. ''Eimeria'' species are considered to be ...
'' species, four things are taken into account: age of the animal, presence of a pathogenic Eimeria
''Eimeria'' is a genus of apicomplexan parasites that includes various species capable of causing the disease coccidiosis in animals such as cattle, poultry and smaller ruminants including sheep and goats. ''Eimeria'' species are considered to be ...
species, infection intensity (oocysts per gram faeces), and presence of symptoms (diarrhea, blood in the faeces).
Epidemiology
Environmental factors can influence how fast new oocysts become infective and management of the animals living conditions and feed and how easily the animals get infected. In general, pathogenic ''Eimeria
''Eimeria'' is a genus of apicomplexan parasites that includes various species capable of causing the disease coccidiosis in animals such as cattle, poultry and smaller ruminants including sheep and goats. ''Eimeria'' species are considered to be ...
'' species, including ''E. zuernii'', can cause three types of disease in a herd that often manifest as outbreaks.
Winter coccidiosis
Coccidiosis is a parasitic disease of the intestinal tract of animals caused by coccidian protozoa. The disease spreads from one animal to another by contact with infected feces or ingestion of infected tissue. Diarrhea, which may become bloody in ...
/eimeriosis – animals becoming more susceptibile to infections due to cold and crowding of the animals facilitate the spread (housing of cattle at the end of a pasture season).
Summer coccidiosis
Coccidiosis is a parasitic disease of the intestinal tract of animals caused by coccidian protozoa. The disease spreads from one animal to another by contact with infected feces or ingestion of infected tissue. Diarrhea, which may become bloody in ...
/eimeriosis – susceptible animals ingesting overwintering oocysts on pastures on turn-out and increased sporulation of new oocysts due to increasing temperatures.[
]
Immunology
Following the initial infection with an ''Eimeria
''Eimeria'' is a genus of apicomplexan parasites that includes various species capable of causing the disease coccidiosis in animals such as cattle, poultry and smaller ruminants including sheep and goats. ''Eimeria'' species are considered to be ...
'' species the animal usually is protected by immunity to that species, and is less likely to develop disease. The level of immunity depend on the amount of oocysts that infected the animal. Heavy infections with ''Eimeria zuernii'' in calves can produce more of the acute phase proteins haptoglobin
Haptoglobin (abbreviated as Hp) is the protein that in humans is encoded by the ''HP'' gene. In blood plasma, haptoglobin binds with high affinity to ''free'' hemoglobin released from erythrocytes, and thereby inhibits its deleterious oxidative ...
and serum amyloid A
Serum amyloid A (SAA) proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma. Different isoforms of SAA are expressed constitutively (constitutive SAAs) at different levels or in response to inflammato ...
and reduce weight gain, when symptoms of coccidiosis can be observed (patent period).
Response to environmental factors
The majority of the parasites life is in the environment and both survival of the parasite as well as developing into an infective oocysts depends on these factors. The time from when the parasite has left the animal in the faeces inside an oocyst and has developed in to a parasite that can infect new animals, is called the sporulation time. High humidity and temperature can speed up the sporulation time and facilitate new infections faster, which can lead to regular outbreaks of coccidiosis.[
Unsporulated ''Eimeria zuernii'' oocysts can handle −18 degrees Celsius for a month and still be able to sporulate.]
References
{{Taxonbar, from=Q56152643
Conoidasida
Veterinary protozoology