Efferent nerve fibers refer to axonal projections that ''exit'' a particular region; as opposed to

afferent Afferent may refer to: Anatomical structures Meaning "conveying towards a center": * Afferent arterioles, blood vessels that supply the nephrons * Afferent lymphatic vessels, lymph vessels that carry lymph to a lymph node * Afferent nerve fiber ...

projections that ''arrive'' at the region. These terms have a slightly different meaning in the context of the peripheral nervous system (PNS) and central nervous system (CNS). The efferent fiber is a long process projecting far from the neuron's body that carries

nerve impulses An action potential occurs when the membrane potential of a specific cell location rapidly rises and falls. This depolarization then causes adjacent locations to similarly depolarize. Action potentials occur in several types of animal cells, ...

away from the central nervous system toward the peripheral effector organs (mainly

muscle Skeletal muscles (commonly referred to as muscles) are organs of the vertebrate muscular system and typically are attached by tendons to bones of a skeleton. The muscle cells of skeletal muscles are much longer than in the other types of muscl ...

s and

gland In animals, a gland is a group of cells in an animal's body that synthesizes substances (such as hormones) for release into the bloodstream (endocrine gland) or into cavities inside the body or its outer surface (exocrine gland). Structure De ...

s). A bundle of these fibers is called an efferent nerve (if it connects to muscles, then it is a motor nerve). The opposite direction of neural activity is

conduction, which carries impulses by way of the

afferent nerve fiber Afferent nerve fibers are the axons (nerve fibers) carried by a sensory nerve that relay sensory information from sensory receptors to regions of the brain. Afferent projections ''arrive'' at a particular brain region. Efferent nerve fibers a ...

s of sensory neurons. In the nervous system there is a "closed loop" system of sensation, decision, and reactions. This process is carried out through the activity of sensory neurons,

interneuron Interneurons (also called internuncial neurons, relay neurons, association neurons, connector neurons, intermediate neurons or local circuit neurons) are neurons that connect two brain regions, i.e. not direct motor neurons or sensory neurons. I ...

s, and motor neurons. In the CNS, afferent and efferent projections can be from the perspective of any given brain region. That is, each brain region has its own unique set of afferent and efferent projections. In the context of a given brain region, afferents are arriving fibers while efferents are exiting fibers.

Structure

Motor nerve

The efferent nerve fibers of motor neurons are involved in

control, both

skeletal A skeleton is the structural frame that supports the body of an animal. There are several types of skeletons, including the exoskeleton, which is the stable outer shell of an organism, the endoskeleton, which forms the support structure inside ...

and

smooth muscle Smooth muscle is an involuntary non-striated muscle, so-called because it has no sarcomeres and therefore no striations (''bands'' or ''stripes''). It is divided into two subgroups, single-unit and multiunit smooth muscle. Within single-unit mus ...

. The cell body of the motor neuron is connected to a single, long axon and several shorter dendrites projecting out of the cell body itself. This axon then forms a

neuromuscular junction A neuromuscular junction (or myoneural junction) is a chemical synapse between a motor neuron and a muscle fiber. It allows the motor neuron to transmit a signal to the muscle fiber, causing muscle contraction. Muscles require innervation to ...

with the effectors. The cell body of the motor neuron is satellite-shaped. The motor neuron is present in the grey matter of the spinal cord and

medulla oblongata The medulla oblongata or simply medulla is a long stem-like structure which makes up the lower part of the brainstem. It is anterior and partially inferior to the cerebellum. It is a cone-shaped neuronal mass responsible for autonomic (involun ...

, and forms an electrochemical pathway to the effector organ or muscle. Besides motor nerves, there are efferent sensory nerves that often serve to adjust the sensitivity of the signal relayed by the afferent sensory nerve.

Types

There are three types of efferent fibers: general somatic efferent fibers (GSE), general visceral efferent fibers (GVE) and special visceral efferent fibers (SVE). Subtypes of general somatic efferent fibers include:

alpha motor neuron Alpha (α) motor neurons (also called alpha motoneurons), are large, multipolar lower motor neurons of the brainstem and spinal cord. They innervate extrafusal muscle fibers of skeletal muscle and are directly responsible for initiating their con ...

s (α) – these target extrafusal muscle fibers, and gamma motor neurons (γ) that target intrafusal muscle fibers. Beta motor neurons target both types of muscle fiber and there are two types known as ''static'' and ''dynamic''.

Etymology and mnemonics

Both afferent and efferent come from

French French (french: français(e), link=no) may refer to: * Something of, from, or related to France ** French language, which originated in France, and its various dialects and accents ** French people, a nation and ethnic group identified with Franc ...

, evolved from Latin (the basis of many terms in medicine and biology) for the terms, respectively, ''ad ferens'' (Latin verb ''ferre'': carry), meaning ''carrying into'', and ''ex ferens'', meaning ''carrying away'' (''ad'' literally means ''to'', and ''e'' = ''ex'' means ''from''). ''Ad'' and ''ex'' give an easy mnemonic device for remembering the relationship between ''afferent'' and ''efferent'': ''afferent connection arrives'' and an ''efferent connection exits''. Afferent and efferent are connected to affect and effect through their common Latin roots: Afferent nerves affect the subject, whereas efferent nerves allow the subject to effect change.

References

{{Authority control Peripheral nervous system Medical mnemonics