Edward (Ted) G. D. Tuddenham FMedSci is considered one of the world's leading haematologists having authored over 200 papers in the field. He gained his

Bachelor of Medicine, Bachelor of Surgery Bachelor of Medicine, Bachelor of Surgery ( la, Medicinae Baccalaureus, Baccalaureus Chirurgiae; abbreviated most commonly MBBS), is the primary medical degree awarded by medical schools in countries that follow the tradition of the United King ...

at the

University of London The University of London (UoL; abbreviated as Lond or more rarely Londin in post-nominals) is a federal public research university located in London, England, United Kingdom. The university was established by royal charter in 1836 as a degree ...

in 1968 and his

Membership of the Royal College of Physicians Member may refer to: * Military jury, referred to as "Members" in military jargon * Element (mathematics), an object that belongs to a mathematical set * In object-oriented programming, a member of a class ** Field (computer science), entries in ...

in 1975. Up until 2005 was head of the Haemostasis and Thrombosis Research ( Medical Research Council) Group at

Imperial College Imperial College London (legally Imperial College of Science, Technology and Medicine) is a public research university in London, United Kingdom. Its history began with Prince Albert, consort of Queen Victoria, who developed his vision for a cu ...

. Professor Tuddenham is a pioneer in the field of

haemophilia Haemophilia, or hemophilia (), is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding. This results in people bleeding for a longer time after an injury, easy bruising, ...

and was responsible, along with Frances Rotblat, for the purification and cloning of the

factor VIII Factor VIII (FVIII) is an essential blood-clotting protein, also known as anti-hemophilic factor (AHF). In humans, factor VIII is encoded by the ''F8'' gene. Defects in this gene result in hemophilia A, a recessive X-linked coagulation disorder. ...

gene, which led to the highly effective and safe treatments available to haemophilia sufferers today. In more recent years, he has been actively involved in developing

gene therapy Gene therapy is a medical field which focuses on the genetic modification of cells to produce a therapeutic effect or the treatment of disease by repairing or reconstructing defective genetic material. The first attempt at modifying human DN ...

for haemophilia. The first successful use of gene transfer to convert severe to mild haemophilia B was reported by his group in December 2011.He retired from Directorship of the Katharine Dormandy Centre in July 2011 and is now Emeritus Professor of Haemophilia at

University College London , mottoeng = Let all come who by merit deserve the most reward , established = , type = Public research university , endowment = £143 million (2020) , budget = ...

. He continues to work in the Haemophilia Centre at the

Royal Free Hospital The Royal Free Hospital (also known simply as the Royal Free) is a major teaching hospital in the Hampstead area of the London Borough of Camden. The hospital is part of the Royal Free London NHS Foundation Trust, which also runs services at Barn ...

on gene therapy clinical trials, with the goal of curing all forms of haemophilia.

References

* * * * * * {{DEFAULTSORT:Tuddenham, Edward British haematologists Living people 1944 births Fellows of the Academy of Medical Sciences (United Kingdom) Academics of University College London Physicians of the Royal Free Hospital Academics of Imperial College London