Eamonn Francis Healy (born 25 September 1958) is an Irish-American professor of

chemistry Chemistry is the science, scientific study of the properties and behavior of matter. It is a natural science that covers the Chemical element, elements that make up matter to the chemical compound, compounds made of atoms, molecules and ions ...

organic chemistry Organic chemistry is a subdiscipline within chemistry involving the scientific study of the structure, properties, and reactions of organic compounds and organic materials, i.e., matter in its various forms that contain carbon atoms.Clayden, J.; ...

, and

biochemistry Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and ...

St. Edward's University St. Edward's University is a private, Catholic university in Austin, Texas. It was founded and is operated in the Holy Cross tradition. History Founding and early history St. Edward's University was founded by the Reverend Edward Sorin, CSC ...

Austin, Texas Austin is the capital city of the U.S. state of Texas, as well as the county seat, seat and largest city of Travis County, Texas, Travis County, with portions extending into Hays County, Texas, Hays and Williamson County, Texas, Williamson co ...

, where his research focuses on the design of structure-activity probes to elucidate enzymatic activity. Targets include

HIV-1 The subtypes of HIV include two major types, HIV type 1 (HIV-1) and HIV type 2 (HIV-2). HIV-1 is related to viruses found in chimpanzees and gorillas living in western Africa, while HIV-2 viruses are related to viruses found in the sooty mangabey, ...

integrase, the

c-Kit Proto-oncogene c-KIT is the gene encoding the receptor tyrosine kinase protein known as tyrosine-protein kinase KIT, CD117 (cluster of differentiation 117) or mast/stem cell growth factor receptor (SCFR). Multiple transcript variants encoding diff ...

and src- abl proteins, and the

metalloproteinases A metalloproteinase, or metalloprotease, is any protease enzyme whose catalytic mechanism involves a metal. An example is ADAM12 which plays a significant role in the fusion of muscle cells during embryo development, in a process known as myoge ...

associated with CXCL16 shedding. He was born in

Newcastle West Newcastle West () or simply Newcastle (''An Caisleán Nua'', formerly anglicized Castlenoe) is a town in west County Limerick, Ireland. It is the largest town in the county, excluding Limerick city, It is also the county town, and sits on the ...

County Limerick "Remember Limerick" , image_map = Island_of_Ireland_location_map_Limerick.svg , subdivision_type = Country , subdivision_name = Ireland , subdivision_type1 = Province , subdivision_name1 = Munster , subdivision ...

Ireland Ireland ( ; ga, Éire ; Ulster Scots dialect, Ulster-Scots: ) is an island in the Atlantic Ocean, North Atlantic Ocean, in Northwestern Europe, north-western Europe. It is separated from Great Britain to its east by the North Channel (Grea ...

. He received a doctorate in chemistry in 1984 from the

University of Texas at Austin The University of Texas at Austin (UT Austin, UT, or Texas) is a public research university in Austin, Texas. It was founded in 1883 and is the oldest institution in the University of Texas System. With 40,916 undergraduate students, 11,075 ...

where he was a student of Dr.

Michael J. S. Dewar Michael James Steuart Dewar (24 September 1918 – 10 October 1997) was an American theoretical chemist. Education and early life Dewar was the son of Scottish parents, Annie Balfour (Keith) and Francis Dewar. He received the degrees of Bache ...

. As a member of the Dewar research group he co-authored

Austin Model 1 Austin Model 1, or AM1, is a semi-empirical method for the quantum calculation of molecular electronic structure in computational chemistry. It is based on the Neglect of Differential Diatomic Overlap integral approximation. Specifically, it is a ...

, or AM1, a

semi-empirical Empirical evidence for a proposition is evidence, i.e. what supports or counters this proposition, that is constituted by or accessible to sense experience or experimental procedure. Empirical evidence is of central importance to the sciences and ...

method for the quantum calculation of molecular electronic structure in

computational chemistry Computational chemistry is a branch of chemistry that uses computer simulation to assist in solving chemical problems. It uses methods of theoretical chemistry, incorporated into computer programs, to calculate the structures and properties of m ...

. He appears in

Richard Linklater Richard Stuart Linklater (; born July 30, 1960) is an American film director, producer, and screenwriter. He is known for films that revolve mainly around suburban culture and the effects of the passage of time. His films include the comedies '' ...

's 2001 film ''

Waking Life ''Waking Life'' is a 2001 American experimental adult animated film written and directed by Richard Linklater. The film explores a wide range of philosophical issues, including the nature of reality, dreams and lucid dreams, consciousness, the ...

'' explaining "telescopic" and

technological evolution The term "technological evolution" captures explanations of technological change that draw on mechanisms from evolutionary biology. Evolutionary biology has one of its roots in the book “On the origin of species” by Charles Darwin. In the style ...

. Dr. Healy is married to Shelley Bueche.

Selected publications

*E.F. Healy "In Defense of a Heuristic Interpretation of Quantum Mechanics", J. Chem. Educ. 2010, 87, 559–563. *Eamonn F. Healy, Skylar Johnson, Charles Hauser, and Peter King "Tyrosine kinase inhibition: Ligand binding and conformational change in c-Kit and c-Abl." FEBS Lett. 2009, 583, 2899-2906 *Eamonn F. Healy, Jonathan Sanders, Peter J. King and W. Edward Robinson, Jr "A Docking Study of L-Chicoric Acid with HIV-1 Integrase" J Mol. Graph. Model. 2009, 27, 14. *E. F. Healy, C. G. Wall, M.A. Fox, "Peptide Conformational Analysis using the TRIPOS Force Field", Intl. J. Quant. Chem., 1992, 44, 543. *R.A. Caldwell, H. Misawa, M.J.S. Dewar, E.F. Healy,"An Unusually Large Secondary Deuterium Isotope Effect",

J. Am. Chem. Soc. The ''Journal of the American Chemical Society'' is a weekly peer-reviewed scientific journal that was established in 1879 by the American Chemical Society. The journal has absorbed two other publications in its history, the ''Journal of Analytic ...

1987, 109, 6869. *M.J.S. Dewar, E. G. Zoebisch, E.F. Healy, J. J. P. Stewart,"AM1: A New General Purpose Quantum Mechanical Molecular Model",

1985, 107, 3902. *M.J.S. Dewar, E.F. Healy, J. J. P. Stewart,"Location of Transition States in Reaction mechanisms", J. Chem. Soc., Faraday Trans. 2 1984, 80, 227. *M.J.S. Dewar, E.F. Healy, "Why Life Exists",

Organometallics ''Organometallics'' is a biweekly journal published by the American Chemical Society. Its area of focus is organometallic and organometalloid chemistry. This peer-reviewed journal has an impact factor of 3.837 as reported by the 2021 Journal Citat ...

1982, 1, 1705.

External links

Webpage at stedwards.edu
University of Texas at Austin College of Natural Sciences alumni 21st-century American chemists 21st-century Irish chemists American science teachers 1958 births Living people Computational chemists People from Newcastle West Irish emigrants to the United States Scientists from County Limerick {{US-chemist-stub

See also

Selected publications

External links