Eyes absent homolog 2 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, res ...
that in humans is encoded by the ''EYA2''
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
Function
This gene encodes a member of the
eyes absent (EYA) subfamily of proteins. The encoded protein may be post-translationally modified and may play a role in eye development. A similar protein in mice can act as a transcriptional activator. Five transcript variants encoding three distinct isoforms have been identified for this gene.
Interactions
EYA2 has been shown to
interact
Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human rights of children with intersex traits. The organizati ...
with
GNAI2
Guanine nucleotide-binding protein G(i), alpha-2 subunit is a protein that in humans is encoded by the ''GNAI2'' gene.
Interactions
GNAI2 has been shown to interact with:
* EYA2,
* GPSM2,
* Interleukin 8 receptor, alpha,
* MDFI,
* RGS5, ...
and
GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha is a protein that in humans is encoded by the ''GNAZ'' gene.
Function
The protein encoded by this gene is a member of a G protein subfamily that mediates signal transduction in pertussis tox ...
.
[
]
References
Further reading
*
*
*
*
*
*
*
*
*
*
*
External links
PDBe-KB
provides an overview of all the structure information available in the PDB for Human Eyes absent homolog 2 (EYA2)
{{gene-20-stub