Estrogen-related receptor beta (ERR-β), also known as ESRRB or NR3B2 (nuclear receptor subfamily 3, group B, member 2), is a
nuclear receptor that in humans is encoded by the ''ESRRB'' (Estrogen Related Receptor Beta)
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
Function
ESRRB has been shown to be vital for the transition between a
naïve pluripotent and primed pluripotent state in mammalian cells, and
NANOG controls the expression of ESRRB in this scenario.
References
Further reading
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{{Estrogen-related receptor modulators
Intracellular receptors
Transcription factors