Early growth response protein 3 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
in humans, encoded by the ''EGR3''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
The gene encodes a
transcriptional regulator
In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity. A single gene can be regulated in a range of ways, from alt ...
that belongs to the
EGR family of C2H2-type
zinc-finger
A zinc finger is a small protein structural motif that is characterized by the coordination of one or more zinc ions (Zn2+) in order to stabilize the fold. It was originally coined to describe the finger-like appearance of a hypothesized struct ...
proteins. It is an immediate-early growth response gene which is induced by
mitogenic
A mitogen is a small bioactive protein or peptide that induces a cell to begin cell division, or enhances the rate of division (mitosis). Mitogenesis is the induction (triggering) of mitosis, typically via a mitogen. The mechanism of action of a ...
stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controlling
biological rhythm
Biological rhythms are repetitive biological processes. Some types of biological rhythms have been described as biological clocks. They can range in frequency from microseconds to less than one repetitive event per decade. Biological rhythms are st ...
. It may also play a role in
muscle
Skeletal muscles (commonly referred to as muscles) are organs of the vertebrate muscular system and typically are attached by tendons to bones of a skeleton. The muscle cells of skeletal muscles are much longer than in the other types of muscl ...
development.
References
Further reading
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External links
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Transcription factors
{{gene-8-stub