EA-1763,John B. Samuel, Elwin C. Penski, John J. Callahan. PHYSICAL PROPERTIES OF STANDARD AGENTS, CANDIDATE AGENTS, AND RELATED COMPOUNDS AT SEVERAL TEMPERATURES (U). p 24 and 279. O-PPVX, V1 or propyl S-2-diisopropylaminoethylmethylphosphonothiolate, is a military-grade neurotoxic organophosphonate

nerve agent Nerve agents, sometimes also called nerve gases, are a class of organic chemicals that disrupt the mechanisms by which nerves transfer messages to organs. The disruption is caused by the blocking of acetylcholinesterase (AChE), an enzyme that ...

related to VX as it the propyl analogue of VX. It is part of the V-series.

Chemical characteristics

Little information about EA-1763's physicochemical properties has been reported. V1 is a more viscous and less dense liquid than VX. It is colorless, odorless and tasteless in its pure form. Impure, or in the crude form, it has a characteristic viscous amber color, giving it an appearance similar to motor oil. The impure form varies several shades of amber, from a viscous liquid of a transparent pale yellow color to a pasty liquid of a semi-transparent and cloudy dirty amber color. The smell varies from engine oil to an offensive brew of

organosulfur compounds Organosulfur compounds are organic compounds that contain sulfur. They are often associated with foul odors, but many of the sweetest compounds known are organosulfur derivatives, e.g., saccharin. Nature abounds with organosulfur compounds—sulfur ...

and organoamines.Ledgard, J. A Laboratory History of Chemical Warfare Agents. p 223-225. Its larger alkane chain pushes its melting point above that of VX. The estimated solubility of V1 in water is 4 times lower compared to VX (6.8 g/L of water at 25 °C). V1 has high solubility in organic solvents and other non-polar compounds. The stability of V1 is roughly the same as that of VX in either environment. Higher insolubility and lower volatility can slow down the process. A vapor pressure at least 3 times lower than VX is speculated. The longer alkane chain tends to stabilize the induction of electrons from P to O, making P less electrophilic. It is expected that the persistence of V1 is slightly higher than that of VX, estimating the hydrolysis rate between ethyl and n-propyl paraoxon, is 1.6 times more persistent in neutral medium.CHEMICAL REVIEWS VOLUME6 4, NUMBER 4. JULY 24, 1964. page 318. The lower volatility and minimal persistence difference makes VX preferable to V1.cit-OPDC. The preparatory manual to chemical warfare. Vol 1: V1

Preparation

It is prepared by the same route as VX using

propanol There are two isomers of propanol. * 1-Propanol, ''n''-propanol, or propan-1-ol : CH3CH2CH2OH, the most common meaning *2-Propanol, Isopropyl alcohol, isopropanol, or propan-2-ol : (CH3)2CHOH See also * Propanal (propionaldehyde) differs in sp ...

instead of

ethanol Ethanol (abbr. EtOH; also called ethyl alcohol, grain alcohol, drinking alcohol, or simply alcohol) is an organic compound. It is an Alcohol (chemistry), alcohol with the chemical formula . Its formula can be also written as or (an ethyl ...

References

{{Chemical agents V-series nerve agents Phosphonothioates Chemical weapons of the United States Diisopropylamino compounds