In complexation catalysis, the term dynamic binding refers to any stabilizing interaction that is stronger at the transition state level than in the reactant-catalyst complex.
Being directly related to
transition state
In chemistry, the transition state of a chemical reaction is a particular configuration along the reaction coordinate. It is defined as the state corresponding to the highest potential energy along this reaction coordinate. It is often marked wi ...
stabilization, dynamic binding is the very hearth of complexation catalysis. It was defined by
A.J. Kirby in 1996 as opposed to the
passive binding, ''i.e.'' the whole of interactions that are equally strong at the
reactant
In chemistry, a reagent ( ) or analytical reagent is a substance or compound added to a system to cause a chemical reaction, or test if one occurs. The terms ''reactant'' and ''reagent'' are often used interchangeably, but reactant specifies a ...
and the
transition state
In chemistry, the transition state of a chemical reaction is a particular configuration along the reaction coordinate. It is defined as the state corresponding to the highest potential energy along this reaction coordinate. It is often marked wi ...
level.
[ A.J. Kirby ]Angewandte Chemie International Edition
''Angewandte Chemie'' (, meaning "Applied Chemistry") is a weekly peer-reviewed scientific journal that is published by Wiley-VCH on behalf of the German Chemical Society (Gesellschaft Deutscher Chemiker). Publishing formats include feature-length ...
1996 35 706–724.
See also
*
Catalysis
Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recyc ...
References
{{Reflist
Physical organic chemistry