Downie bodies, also known as a type of A-type inclusion, are a type of

inclusion body Inclusion bodies are aggregates of specific types of protein found in neurons, a number of tissue cells including red blood cells, bacteria, viruses, and plants. Inclusion bodies of aggregations of multiple proteins are also found in muscle cells ...

associated with

cowpox Cowpox is an infectious disease caused by the ''cowpox virus'' (CPXV). It presents with large blisters in the skin, a fever and swollen glands, historically typically following contact with an infected cow, though in the last several decades more ...

. They are named for

Allan Watt Downie Allan Watt Downie FRS (5 September 1901 – 26 January 1988) was a Scottish microbiologist involved in the eradication of smallpox. He was elected a Fellow of the Royal Society Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is ...

. A Downie body is different from a ''Downey cell'' which is a

reactive lymphocyte In immunology, reactive lymphocytes or variant lymphocytes are cytotoxic (CD8+) lymphocytes that become large as a result of antigen stimulation. Typically, they can be more than 30 μm in diameter with varying size and shape. The nucleus of ...

. They are named for Hal Downey.

References

Viral diseases Histopathology {{virus-stub