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Dover's powder was a traditional medicine against
cold Cold is the presence of low temperature, especially in the atmosphere. In common usage, cold is often a subjective perception. A lower bound to temperature is absolute zero, defined as 0.00K on the Kelvin scale, an absolute thermodynamic ...
and
fever Fever, also referred to as pyrexia, is defined as having a temperature above the normal range due to an increase in the body's temperature set point. There is not a single agreed-upon upper limit for normal temperature with sources using val ...
developed by Thomas Dover. It is no longer in use in modern medicine, but may have been in use at least through the 1960s. A 1958 source describes Dover's Powder as follows: "Powder of Ipecacuanha and Opium (''B.P.'', ''Egyp. P.'', ''Ind. P.''). Pulv. Ipecac. et Opii; Ipecac and Opium Powder (''U.S.N.F.''); Dover's Powder; Compound Ipecacuanha Powder. Prepared ipecacuanha, 10 g., powdered opium 10 g., lactose 80 g. It contains 1% of anhydrous morphine. ''Dose:'' 320 to 640 mg. (5 to 10 grains). Many foreign pharmacies include a similar powder, sometimes with potassium sulphate or with equal parts of potassium nitrate and potassium sulphate in place of lactose; ''max. single dose'' 1 to 1.5 g. and max. in 24 hours 4 to 6 g."''The Extra Pharmacopoeia Martindale''. Vol. 1, 24th edition. London: The Pharmaceutical Press, 1958, page 812. This reference also cites "Tablets of Ipecacuanha and Opium (''B.P.'', ''Ind. P.'') Tab. Ipecac. et Opii (''B.N.F.''), Dover's Powder Tablets. Unless otherwise specified tablets each containing 5 grains of powder of ipecacuanha and opium are supplied." Named from Doctor Thomas Dover, an
English English usually refers to: * English language * English people English may also refer to: Peoples, culture, and language * ''English'', an adjective for something of, from, or related to England ** English national id ...
physician A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through th ...
of the eighteenth century who first prepared it, the powder was an old preparation of powder of ipecacuanha (which was formerly used to produce
syrup of ipecac Syrup of ipecac (), or simply ipecac, is a drug that was once widely used as an expectorant (in low doses) and a rapid-acting emetic (in higher doses). It is obtained from the dried rhizome and roots of the ipecacuanha plant (''Carapichea ipeca ...
),
opium Opium (or poppy tears, scientific name: ''Lachryma papaveris'') is dried latex obtained from the seed capsules of the opium poppy '' Papaver somniferum''. Approximately 12 percent of opium is made up of the analgesic alkaloid morphine, which ...
in powder, and
potassium sulfate Potassium sulfate (US) or potassium sulphate (UK), also called sulphate of potash (SOP), arcanite, or archaically potash of sulfur, is the inorganic compound with formula K2SO4, a white water-soluble solid. It is commonly used in fertilizers, prov ...
. The powder was largely used in domestic practice to induce
sweating Perspiration, also known as sweating, is the production of fluids secreted by the sweat glands in the skin of mammals. Two types of sweat glands can be found in humans: eccrine glands and apocrine glands. The eccrine sweat glands are distri ...
, to defeat the advance of a "cold" and at the beginning of any attack of
fever Fever, also referred to as pyrexia, is defined as having a temperature above the normal range due to an increase in the body's temperature set point. There is not a single agreed-upon upper limit for normal temperature with sources using val ...
. It was also known by the name ''pulvis ipecacuanhae et opii''. To obtain the greatest benefits from its use as a sudorific, it was recommended that copious drafts of some warm and harmless drink be ingested after the use of the powder. The following excerpt from a report penned by a Doctor Sharp, employed in the British naval service in the West Indies, in this case, in Trinidad, in 1818, illustrates its use. He writes :
At this period, thirty cases of acute dysentery also occurred amongst them and although nineteen of the number were men who arrived in the island from Europe on the 1st and 12th of June, yet, the symptoms even in them were equally as mild as in the assimilated soldier, and the disease yielded to the common remedies – viz – bleeding when the state of the vascular system appeared to indicate the use of it, but in general, saline purgatives in small and repeated quantities were only necessary with small doses at bed time, of
calomel Calomel is a mercury chloride mineral with formula Hg2Cl2 (see mercury(I) chloride). The name derives from Greek ''kalos'' (beautiful) and ''melas'' (black) because it turns black on reaction with ammonia. This was known to alchemists. Calom ...
and opium, infusion of ipecacuanha or Dover’s powder, and this with tonics, moderate use of port wine and a light farinaceous diet generally and speedily accomplished a perfect case.


India

Dover's powder was banned in India in 1994.


References


External links

* History of pharmacy Powders {{Treatment-stub