Sir Douglass Matthew Turnbull is

Professor Professor (commonly abbreviated as Prof.) is an Academy, academic rank at university, universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a "person who pr ...

Neurology Neurology (from el, wikt:νεῦρον, νεῦρον (neûron), "string, nerve" and the suffix wikt:-logia, -logia, "study of") is the branch of specialty (medicine), medicine dealing with the diagnosis and treatment of all categories of co ...

Newcastle University Newcastle University (legally the University of Newcastle upon Tyne) is a UK public university, public research university based in Newcastle upon Tyne, North East England. It has overseas campuses in Singapore and Malaysia. The university is ...

, an Honorary Consultant Neurologist at Newcastle upon Tyne Hospitals NHS Foundation Trust and a director of the

Wellcome Trust The Wellcome Trust is a charitable foundation focused on health research based in London, in the United Kingdom. It was established in 1936 with legacies from the pharmaceutical magnate Henry Wellcome (founder of one of the predecessors of Glaxo ...

Centre for Mitochondrial Research.

Education

Turnbull was educated at

, where he was awarded a

Bachelor of Medicine, Bachelor of Surgery Bachelor of Medicine, Bachelor of Surgery ( la, Medicinae Baccalaureus, Baccalaureus Chirurgiae; abbreviated most commonly MBBS), is the primary medical degree awarded by medical schools in countries that follow the tradition of the United King ...

and qualifying as a junior doctor. He was subsequently awarded a

PhD PHD or PhD may refer to: * Doctor of Philosophy (PhD), an academic qualification Entertainment * '' PhD: Phantasy Degree'', a Korean comic series * ''Piled Higher and Deeper'', a web comic * Ph.D. (band), a 1980s British group ** Ph.D. (Ph.D. albu ...

for research investigating

Mitochondria A mitochondrion (; ) is an organelle found in the Cell (biology), cells of most Eukaryotes, such as animals, plants and Fungus, fungi. Mitochondria have a double lipid bilayer, membrane structure and use aerobic respiration to generate adenosi ...

l cytopathies.

Research

Turnbull's research investigates techniques for improving the lives of patients with mitochondrial disease. he has supervised 35 successful PhD students to completion and is currently supervising 10 PhD students in progress. His most highly cited research has been published in world leading

peer review Peer review is the evaluation of work by one or more people with similar competencies as the producers of the work (peers). It functions as a form of self-regulation by qualified members of a profession within the relevant field. Peer review ...

ed scientific journals such as ''

Nature Nature, in the broadest sense, is the physics, physical world or universe. "Nature" can refer to the phenomenon, phenomena of the physical world, and also to life in general. The study of nature is a large, if not the only, part of science. ...

'', ''

Nature Genetics ''Nature Genetics'' is a peer-reviewed scientific journal published by Nature Portfolio. It was established in 1992. It covers research in genetics. The chief editor is Tiago Faial. The journal encompasses genetic and functional genomic studi ...

'', ''

Nature Reviews Genetics ''Nature Reviews Genetics'' is a monthly review journal published by Nature Portfolio. It was established in 2000 and covers the full breadth of modern genetics. The editor-in-chief is Linda Koch. The journal publishes review and perspective arti ...

,'' the '' American Journal of Human Genetics,'' and the '' Journal of Clinical Investigation''. His research has been funded by the

, the Biotechnology and Biological Sciences Research Council (BBSRC) and the

Medical Research Council (MRC) The Medical Research Council (MRC) is responsible for co-coordinating and funding medical research in the United Kingdom. It is part of United Kingdom Research and Innovation (UKRI), which came into operation 1 April 2018, and brings together t ...

Awards and honours

Turnbull delivered the

Goulstonian Lectures The Goulstonian Lectures are an annual lecture series given on behalf of the Royal College of Physicians in London. They began in 1639. The lectures are named for Theodore Goulston (or Gulston, died 1632), who founded them with a bequest A beque ...

in 1992 and was awarded the Jean Hunter Prize in 2003, both by the Royal College of Physicians. He was elected a Fellow of the Academy of Medical Sciences in 2004. Turnbull was knighted in the

2016 Birthday Honours The 2016 Queen's Birthday Honours are appointments by some of the 16 Commonwealth realms of Queen Elizabeth II to various orders and honours to reward and highlight good works by citizens of those countries. The Birthday Honours are awarded as pa ...

. According to the BBC, his knighthood was awarded for "creating a groundbreaking IVF technique which prevents disabling

genetic disorder A genetic disorder is a health problem caused by one or more abnormalities in the genome. It can be caused by a mutation in a single gene (monogenic) or multiple genes (polygenic) or by a chromosomal abnormality. Although polygenic disorders ...

s from being passed on to future generations". This technique uses

mitochondrial donation Mitochondrial replacement therapy (MRT), sometimes called mitochondrial donation, is the replacement of mitochondria in one or more cells to prevent or ameliorate disease. MRT originated as a special form of in vitro fertilisation in which some or ...

, also known as "three-person babies". Turnbull was awarded the

Buchanan Medal The Buchanan Medal is awarded by the Royal Society "in recognition of distinguished contribution to the medical sciences generally". The award was created in 1897 from a fund to the memory of London physician Sir George Buchanan (1831–1895). It ...

for outstanding contributions to biomedicine particularly in relation to mitochondrial disease, including the development of a method to prevent their transmission.

References

{{DEFAULTSORT:Turnbull, Douglas Matthew British neurologists Living people Fellows of the Academy of Medical Sciences (United Kingdom) Knights Bachelor NIHR Senior Investigators Year of birth missing (living people)