Doravirine, sold under the brand name Pifeltro, is a
non-nucleoside reverse transcriptase inhibitor
Reverse-transcriptase inhibitors (RTIs) are a class of antiretroviral drugs used to treat HIV infection or AIDS, and in some cases hepatitis B. RTIs inhibit activity of reverse transcriptase, a viral DNA polymerase that is required for replication ...
medication developed by
Merck & Co. for use in the treatment of
HIV/AIDS
Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual ...
.
Doravirine was approved for medical use in the United States in August 2018.
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Nitriles
Trifluoromethyl compounds
Merck & Co. brands
Nitrogen heterocycles
Non-nucleoside reverse transcriptase inhibitors
Chloroarenes
Phenol ethers
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