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Doravirine, sold under the brand name Pifeltro, is a
non-nucleoside reverse transcriptase inhibitor Reverse-transcriptase inhibitors (RTIs) are a class of antiretroviral drugs used to treat HIV infection or AIDS, and in some cases hepatitis B. RTIs inhibit activity of reverse transcriptase, a viral DNA polymerase that is required for replication ...
medication developed by Merck & Co. for use in the treatment of
HIV/AIDS Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual ...
. Doravirine was approved for medical use in the United States in August 2018.


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* Nitriles Trifluoromethyl compounds Merck & Co. brands Nitrogen heterocycles Non-nucleoside reverse transcriptase inhibitors Chloroarenes Phenol ethers {{antiinfective-drug-stub