The fourth season of ''

House A house is a single-unit residential building. It may range in complexity from a rudimentary hut to a complex structure of wood, masonry, concrete or other material, outfitted with plumbing, electrical, and heating, ventilation, and air c ...

'', also known as ''House, M.D.'', premiered on September 25, 2007 and ended May 19, 2008. Having previously fired Chase, and with Foreman and Cameron quitting,

starts a competition between 40 applicants for the vacant positions. He eventually narrows them down to seven, firing one each episode. In the episode "Games", he fires

Amber Volakis ''House'' (also known as ''House, M.D.'') is an American medical drama television series created by David Shore for Fox Broadcasting Company, Fox. It ran for eight seasons from November 16, 2004, to May 21, 2012. It features the life of Dr. G ...

(

Anne Dudek Anne Louise Dudek (born March 22, 1975) is an American actress. She is known for portraying Tiffany Wilson in the 2004 film ''White Chicks'', Danielle Brooks in the television series ''Covert Affairs'', Dr. Amber Volakis on the series ''House'', ...

), hiring Dr. Chris Taub (

Peter Jacobson Peter Jacobson (born March 24, 1965) is an American actor. He is best known for his portrayal of Dr. Chris Taub on the Fox medical drama series ''House''. He also starred on the USA Network science fiction drama ''Colony'' as former Proxy Snyder ...

), Dr. Lawrence Kutner (

Kal Penn Kalpen Suresh Modi ( born April 23, 1977), known professionally as Kal Penn, is an American actor, author, and former White House staff member in the Barack Obama administration. As an actor he is known for his portrayals of Kumar Patel in t ...

) and Dr. Remy "Thirteen" Hadley (

Olivia Wilde Olivia Wilde (born Olivia Jane Cockburn, , March 10, 1984) is an American actress and director. She played Thirteen (House), Remy "Thirteen" Hadley on the medical-drama television series ''House (TV series), House'' (2007–2012), and appeared ...

) as his new team. Dr. Foreman rejoins the team after his dismissal from another hospital. Meanwhile, Amber begins a relationship with Wilson. When production of the season was interrupted by the 2007–2008 Writers Guild of America strike, the number of episodes was reduced to 16 instead of the planned 24. Executive producer Katie Jacobs explained that it was hard for the writers to finish the story arcs started during the season with eight fewer episodes. Season four also introduced seven actors to the cast; in addition to Jacobson, Penn, and Wilde, who became regulars,

Andy Comeau Andy Comeau (born October 19, 1970) is an American actor and musician. He is best known for playing Theodore "Teddy" Huffstodt on the Showtime series '' Huff'' (2004–2006). He was also featured in the fourth season of the series ''House'' as Dr ...

portrayed Travis Brennan, an

epidemiologist Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population, and application of this knowledge to prevent diseases. It is a cornerstone ...

;

Edi Gathegi Edi Mūe Gathegi (; born March 10, 1979) is a Kenyan-American actor. He appeared as a recurring character, Dr. Jeffrey Cole (aka "Big Love"), in the television series ''House'', as Cheese in the 2007 film ''Gone Baby Gone'', Laurent in the films ...

played Jeffrey Cole, a

geneticist A geneticist is a biologist or physician who studies genetics, the science of genes, heredity, and variation of organisms. A geneticist can be employed as a scientist or a lecturer. Geneticists may perform general research on genetic process ...

;

Carmen Argenziano Carmen Antimo Argenziano (October 27, 1943February 10, 2019) was an American actor who appeared in over 73 movies and around 100 television movies or episodes. He was best known for playing Jacob Carter on ''Stargate SG-1''. He had recurring role ...

appeared as Henry Dobson, a former medical school admissions officer; and Anne Dudek portrayed Amber Volakis, an interventional

radiologist Radiology ( ) is the medical specialty that uses medical imaging to diagnose diseases and guide treatment within the bodies of humans and other animals. It began with radiography (which is why its name has a root referring to radiation), but tod ...

. Each of the four departed the show after elimination, except for Volakis, who remained recurring until the finale, having started a relationship with Wilson.

Cast and characters

Main cast

Hugh Laurie James Hugh Calum Laurie (; born 11 June 1959) is an English actor, comedian, singer, musician and writer. He first gained professional recognition as a member of the English comedy double act Fry and Laurie with Stephen Fry. Fry and Laurie act ...

as Dr. Gregory House *

Lisa Edelstein Lisa Edelstein ( ; born May 21, 1966) is an American actress and artist. She is known for playing Dr. Lisa Cuddy on the Fox medical drama series ''House'' (2004–2011). Between 2014 and 2018, Edelstein starred as Abby McCarthy in the Bravo s ...

as Dr. Lisa Cuddy *

Omar Epps Omar Hashim Epps (born July 20, 1973) is an American actor, rapper, and producer. Epps's film roles include ''Juice (1992 film), Juice'', ''Higher Learning'', ''The Wood'', ''In Too Deep (1999 film), In Too Deep'', and ''Love & Basketball''. His ...

as Dr. Eric Foreman *

Robert Sean Leonard Robert Lawrence Leonard (born February 28, 1969), known professionally as Robert Sean Leonard, is an American actor. He is best known for his portrayal of Neil Perry in the drama film ''Dead Poets Society'' (1989) and Dr. James Wilson in the med ...

as Dr. James Wilson *

Jennifer Morrison Jennifer Marie Morrison (born April 12, 1979) is an American actress and director. She is most known for her roles as Dr. Allison Cameron in the medical-drama series ''House'' (2004–2012) and Emma Swan in the ABC adventure-fantasy series '' ...

as Dr. Allison Cameron *

Jesse Spencer Jesse Gordon Spencer (born 12 February 1979) is an Australian actor. He is known for his roles as Billy Kennedy on the Australian soap opera ''Neighbours'' (1994–2000, 2005, 2022), for which he was nominated for two Logie Awards, Dr. Robert ...

as Dr. Robert Chase

Recurring cast

as Dr. Chris Taub *

as Dr. Lawrence Kutner *

as Dr. Remy 'Thirteen' Hadley *

as Dr. Amber Volakis *

as Dr. Jeffrey "Big Love" Cole *

as Dr. Travis "Grumpy" Brennan *

Henry Dobson Henry Dobson (24 December 1841 – 10 October 1918) was an Australian politician, who served as a member of the Tasmanian House of Assembly and later of the Australian Senate. He was the 17th Premier of Tasmania from 17 August 1892 to 14 Ap ...

Michael Michele Michael Michele Williams (born August 30, 1966) is an American actress and fashion designer. She began her career on stage before appearing opposite Wesley Snipes in the 1991 film ''New Jack City''. In the 1990s, Michele had leading roles in t ...

as Dr. Samira Terzi * Meera Simhan as Dr. Jody Desai * Melinda Dahl as Doctor #15A * Caitlin Dahl as Doctor #15B * Kathryn Adams as Doctor #23 *

Jennifer Crystal Foley Jennifer Amie Crystal Foley (born January 26, 1973) is an American actress. She is best known for her roles as Christie Parker in ''Once and Again'' and Rachel Taub on ''House A house is a single-unit residential building. It may range i ...

Rachel Taub : ''For more detailed character information, see List of House characters''. Below is a list of actors and actresses that are or were part of the cast of the American drama television series ''House''. The show's main stars have included, at so ...

* Maurice Godin as Dr. Lawrence Hourani

Guest cast

Michael Adler, Kristina Anapau, Julie Ariola,

Essence Atkins Essence Uhura Atkins (born February 7, 1972) is an American actress. She began her career appearing on television sitcoms, before her regular role on the African-American prime-time drama '' Under One Roof'' (CBS, 1995). Atkins is best known for ...

Rob Benedict Rob Benedict (born September 21, 1970) is an American actor and writer. His near 30 year career includes more than 90 television and movie credits. He is best known for his work on the television series ''Supernatural (American TV series), Su ...

, Eli Bildner, Joel Bissonnette, David Campbell, Matt DeCaro, Dan Desmond, Conor Dubin, Amy Dudgeon,

Fred Durst William Frederick Durst (born Frederick Allen Mayne III; August 20, 1970) is an American rapper, singer, songwriter, actor, and director. He is the frontman and lyricist of the nu metal band Limp Bizkit, formed in 1994, with whom he has release ...

, Laurie Fortier, Heather Fox,

Jennifer Hall Jennifer Hall (born October 20, 1977) is an American actress most known for starring as a fictionalized version of herself on the HBO series ''Unscripted'' and playing Missy on the NBC sitcom '' Up All Night''. Early career Jennifer Hall studi ...

, Henry Hayashi,

Jeff Hephner Jeffrey Hephner is an American actor, best known for the role of Jeff Clarke, first on the NBC television series '' Chicago Fire'' and then on its sister show, '' Chicago Med''. On film, he co-starred with Jennifer Garner in the action thrill ...

Charlie Hofheimer Charles Nathan Hofheimer (born April 17, 1981) is an American actor. Beginning his career as a child actor, Hofheimer made his film debut in ''Lassie (1994 film), Lassie'' (1994), subsequently appearing in ''Boys (1996 film), Boys'' (1996) and '' ...

Brian Klugman Brian Klugman (born September 15, 1975) is an American actor, screenwriter, and director. In 2012 he debuted as a co-director with Lee Sternthal on the film '' The Words'', which they both co-wrote as well. Early life Klugman was born and rais ...

, Caroline Lagerfelt, Kay Lenz, Jason Lewis,

Liana Liberato Liana Daine Liberato (born August 20, 1995) is an American actress. She played the younger version of the female lead in the 2014 film ''The Best of Me (2014 film), The Best of Me'' and starred in the drama films ''The Last Sin Eater (film), The ...

, Nick McCallum,

Ivana Miličević Ivana Miličević (; born April 26, 1974) is a Croatian-American actress and model based in the United States, best known for her starring roles in the Cinemax action-drama series ''Banshee (TV series), Banshee'' (2013–2016) and The CW science ...

, Pat Millicano,

Janel Moloney Janel Moloney (born October 3, 1969) is an American actress, best known for her role as Donna Moss on the television series ''The West Wing'', a role for which she received nominations for Primetime Emmy Award for Outstanding Supporting Actress ...

Chad Morgan Chadwick William Morgan (11 February 1933 – 1 January 2025) was an Australian country music singer and guitarist known for his vaudeville style of comic country and western and folk songs, his prominent teeth and goofy stage persona. In refe ...

Jason Manuel Olazabal Jason Manuel Olazabal (born October 14, 1973), also just known as Jason Olazabal, is an American actor, known for playing List of Dexter characters#Ramón Prado, Ramon Prado in Showtime (TV network), Showtime TV series ''Dexter (TV series), Dex ...

Holmes Osborne Holmes Osborne (born November 7, 1947) is an American character actor who has worked in film and television, including notable roles in '' That Thing You Do!'' (1996), ''Donnie Darko'' (2001) and '' Southland Tales'' (2007). Career Prior to purs ...

Eyal Podell Eyal Podell (; ; born November 11, 1975) is an Israeli- American actor and screenwriter. He is best known for his portrayals of Professor Adrian Korbel in the soap opera ''The Young and the Restless'', Evram Mintz in '' Defying Gravity'', and Na ...

, Bevin Prince,

Paul Rae Paul Rae (born June 27, 1968) is an American film and television actor. Biography Rae was born Paul Rae Stuart in New Orleans, Louisiana, the son of Jean Rushing and the late Norman Stuart, and was raised in Bogalusa, Washington Parish, Louisian ...

Jeremy Renner Jeremy Lee Renner (born January 7, 1971) is an American actor. He began his career by appearing in independent films such as ''Dahmer (film), Dahmer'' (2002) and ''Neo Ned'' (2005), then supporting roles in bigger films, such as ''S.W.A.T. (20 ...

, Reynaldo Rosales, Jonathan Sadowski,

Mary Kate Schellhardt Mary Kate Schellhardt (born November 1, 1978) is an American actress. She is known for her roles as Ellen in ''What's Eating Gilbert Grape'' (1993), and as Barbara Lovell in Ron Howard's ''Apollo 13 Apollo 13 (April 1117, 1970) was the se ...

Azura Skye Azura Dawn Storozynski (born November 8, 1981), known professionally as Azura Skye, is an American actress who first gained recognition for her role as Jane on The WB television sitcom ''Zoe, Duncan, Jack and Jane''. She also had a 2-episode role ...

Laura Silverman Laura Jane Silverman (born June 10, 1966) is an American actress and the older sister of actress and comedian Sarah Silverman. She acted in '' Sarah Silverman: Jesus Is Magic'' and '' The Sarah Silverman Program'' portraying a fictionalized vers ...

, Scott Alan Smith,

Mira Sorvino Mira Katherine Sorvino (; born ) is an American actress. She rose to stardom with her performance as a prostitute in the comedy film ''Mighty Aphrodite'' (1995), which won her both an Academy Award and a Golden Globe for Academy Award for Best S ...

Douglas Spain Douglas Spain (born April 15, 1974) is an American film and television actor, director and producer. In 1998 Spain was nominated for an Independent Spirit Award in the category of Best Debut Performance for his role in the film ''Star Maps''. In ...

Anthony Starke Anthony Starke is an American actor. He may be best known for his one-episode role in ''Seinfeld'', playing the third-person-speaking character Jimmy in the 1995 episode "The Jimmy", as well as his main cast role as Jack on ''The George Carlin S ...

Khleo Thomas Khaleed "Khleo" Leon Thomas (born January 30, 1989) is an American actor and rapper. First garnering recognition as a child actor with his portrayal Hector "Zero" Zeroni in the film ''Holes'' (2003), he has since appeared in films including '' ...

Steve Valentine Stephen John Valentine (born 26 October 1966) is a British-American actor and magician. He is known for his roles as Nigel Townsend on NBC's crime drama series ''Crossing Jordan'', the voice of Harry Flynn in the video game '' Uncharted 2: Amon ...

, Alex Weed,

Frank Whaley Frank Joseph Whaley (born July 20, 1963) is an American actor, film director, screenwriter, musician and comedian. His roles include Brett in ''Pulp Fiction'', Robby Krieger in ''The Doors'', Jim Dodge in '' Career Opportunities'', young Archie ...

Michael Whaley Michael Whaley is an American film and television actor. He graduated from Culver City High School in 1980. Some of his most known characters are Dr. Wesley 'Wes' Hayes on ''Sisters'', Det. Nathan Brubaker on '' Profiler'', Detective Paul Armstro ...

Chad Willett Chad Willett (born October 10, 1971, in British Columbia), is a Canadian actor and producer who has worked for over 30 years as a professional in film, television and theatre. His selected films include '' Alive'', directed by Frank Marshall and ...

, Thomas F. Wilson, Tom Wright and

Kathleen York Kathleen "Bird" York is an American actress, screenwriter, and Oscar-nominated singer-songwriter recording artist. She was nominated for an Academy Award for Best Original Song for "In the Deep" from the 2004 film '' Crash.'' Life and career E ...

Episodes

DVD releases

References

;General * * ;Specific ;Further reading * * * *