Disease A disease is a particular abnormal condition that negatively affects the structure or function of all or part of an organism, and that is not immediately due to any external injury. Diseases are often known to be medical conditions that a ...

s, both real and fictional, play a significant role in fiction, with certain diseases like

Huntington's disease Huntington's disease (HD), also known as Huntington's chorea, is a neurodegenerative disease that is mostly inherited. The earliest symptoms are often subtle problems with mood or mental abilities. A general lack of coordination and an unst ...

and

tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...

appearing in many books and films.

Pandemic A pandemic () is an epidemic of an infectious disease that has spread across a large region, for instance multiple continents or worldwide, affecting a substantial number of individuals. A widespread endemic (epidemiology), endemic disease wi ...

plagues threatening all human life, such as ''

The Andromeda Strain ''The Andromeda Strain'' is a 1969 techno-thriller novel by Michael Crichton, his first novel under his own name and his sixth novel overall. It is written as a report documenting the efforts of a team of scientists investigating the outbreak of ...

'', are among the many fictional diseases described in literature and film.

Real diseases

Margaret Bernardine Hall - Fantine - Google Art Project

Genuine plagues have formed the central elements of books from

Giovanni Boccaccio Giovanni Boccaccio (, , ; 16 June 1313 – 21 December 1375) was an Italian writer, poet, correspondent of Petrarch, and an important Renaissance humanist. Born in the town of Certaldo, he became so well known as a writer that he was somet ...

's c. 1353 ''

The Decameron ''The Decameron'' (; it, label=Italian, Decameron or ''Decamerone'' ), subtitled ''Prince Galehaut'' (Old it, Prencipe Galeotto, links=no ) and sometimes nicknamed ''l'Umana commedia'' ("the Human comedy", as it was Boccaccio that dubbed Dan ...

'' onwards. Boccaccio tells the tales of ten people of Florence who escape from the

Black Death The Black Death (also known as the Pestilence, the Great Mortality or the Plague) was a bubonic plague pandemic occurring in Western Eurasia and North Africa from 1346 to 1353. It is the most fatal pandemic recorded in human history, causi ...

in their city. The book inspired

Geoffrey Chaucer Geoffrey Chaucer (; – 25 October 1400) was an English poet, author, and civil servant best known for ''The Canterbury Tales''. He has been called the "father of English literature", or, alternatively, the "father of English poetry". He wa ...

's 14th-century ''

Canterbury Tales ''The Canterbury Tales'' ( enm, Tales of Caunterbury) is a collection of twenty-four stories that runs to over 17,000 lines written in Middle English by Geoffrey Chaucer between 1387 and 1400. It is widely regarded as Chaucer's ''magnum opus' ...

'', which similarly tells the stories of people on pilgrimage in a time of plague.

Ingmar Bergman Ernst Ingmar Bergman (14 July 1918 – 30 July 2007) was a Swedish film director, screenwriter, Film producer, producer and playwright. Widely considered one of the greatest and most influential filmmakers of all time, his films are known ...

's 1957 film ''

The Seventh Seal ''The Seventh Seal'' ( sv, Det sjunde inseglet) is a 1957 Swedish historical fantasy film written and directed by Ingmar Bergman. Set in Sweden during the Black Death, it tells of the journey of a medieval knight (Max von Sydow) and a game of ch ...

'' ( sv, Det sjunde inseglet) is set in Denmark during the Black Death, and features a game of chess with

Death Death is the irreversible cessation of all biological functions that sustain an organism. For organisms with a brain, death can also be defined as the irreversible cessation of functioning of the whole brain, including brainstem, and brain ...

personified as a monk-like figure.

Tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...

was a common disease in the 19th century, and it appeared in several major works of

Russian literature Russian literature refers to the literature of Russia and its émigrés and to Russian language, Russian-language literature. The roots of Russian literature can be traced to the Middle Ages, when epics and chronicles in Old East Slavic were c ...

Fyodor Dostoevsky Fyodor Mikhailovich Dostoevsky (, ; rus, Фёдор Михайлович Достоевский, Fyódor Mikháylovich Dostoyévskiy, p=ˈfʲɵdər mʲɪˈxajləvʲɪdʑ dəstɐˈjefskʲɪj, a=ru-Dostoevsky.ogg, links=yes; 11 November 18219 ...

used the theme of the consumptive

nihilist Nihilism (; ) is a philosophy, or family of views within philosophy, that rejects generally accepted or fundamental aspects of human existence, such as objective truth, knowledge, morality, values, or meaning. The term was popularized by Ivan ...

repeatedly, with Katerina Ivanovna in ''

Crime and Punishment ''Crime and Punishment'' ( pre-reform Russian: ; post-reform rus, Преступление и наказание, Prestupléniye i nakazániye, prʲɪstʊˈplʲenʲɪje ɪ nəkɐˈzanʲɪje) is a novel by the Russian author Fyodor Dostoevsky. ...

''; Kirillov in '' The Possessed'', and both Ippolit and Marie in ''

The Idiot ''The Idiot'' ( pre-reform Russian: ; post-reform rus, Идиот, Idiót) is a novel by the 19th-century Russian author Fyodor Dostoevsky. It was first published serially in the journal ''The Russian Messenger'' in 1868–69. The title is an ...

.''

Turgenev Ivan Sergeyevich Turgenev (; rus, links=no, Ива́н Серге́евич Турге́невIn Turgenev's day, his name was written ., p=ɪˈvan sʲɪrˈɡʲe(j)ɪvʲɪtɕ tʊrˈɡʲenʲɪf; 9 November 1818 – 3 September 1883 ( Old Style da ...

did the same with Bazarov in '' Fathers and Sons''. In

English literature English literature is literature written in the English language from United Kingdom, its crown dependencies, the Republic of Ireland, the United States, and the countries of the former British Empire. ''The Encyclopaedia Britannica'' defines E ...

of the

Victorian era In the history of the United Kingdom and the British Empire, the Victorian era was the period of Queen Victoria's reign, from 20 June 1837 until her death on 22 January 1901. The era followed the Georgian period and preceded the Edwardia ...

, major tuberculosis novels include

Charles Dickens Charles John Huffam Dickens (; 7 February 1812 – 9 June 1870) was an English writer and social critic. He created some of the world's best-known fictional characters and is regarded by many as the greatest novelist of the Victorian e ...

's 1848 ''

Dombey and Son ''Dombey and Son'' is a novel by English author Charles Dickens. It follows the fortunes of a shipping firm owner, who is frustrated at the lack of a son to follow him in his footsteps; he initially rejects his daughter's love before eventual ...

'',

Elizabeth Gaskell Elizabeth Cleghorn Gaskell (''née'' Stevenson; 29 September 1810 – 12 November 1865), often referred to as Mrs Gaskell, was an English novelist, biographer and short story writer. Her novels offer a detailed portrait of the lives of many st ...

's 1855 ''

North and South North and South may refer to: Literature * ''North and South'' (Gaskell novel), an 1854 novel by Elizabeth Gaskell * ''North and South'' (trilogy), a series of novels by John Jakes (1982–1987) ** ''North and South'' (Jakes novel), first novel ...

'', and

Mrs. Humphry Ward Mary Augusta Ward (''née'' Arnold; 11 June 1851 – 24 March 1920) was a British novelist who wrote under her married name as Mrs Humphry Ward. She worked to improve education for the poor and she became the founding President of the Women' ...

's 1900 ''Eleanor''.

Albert Camus Albert Camus ( , ; ; 7 November 1913 – 4 January 1960) was a French philosopher, author, dramatist, and journalist. He was awarded the 1957 Nobel Prize in Literature at the age of 44, the second-youngest recipient in history. His work ...

's 1947 '' The Plague'', probably based on

cholera Cholera is an infection of the small intestine by some strains of the bacterium ''Vibrio cholerae''. Symptoms may range from none, to mild, to severe. The classic symptom is large amounts of watery diarrhea that lasts a few days. Vomiting and ...

in 19th-century France, was seen both as fable about the need for people to help each other in the meaningless world seen by

existentialism Existentialism ( ) is a form of philosophical inquiry that explores the problem of human existence and centers on human thinking, feeling, and acting. Existentialist thinkers frequently explore issues related to the meaning, purpose, and valu ...

, and as alluding to the German invasion of France, fresh in Camus's mind.

appears in many novels, such as

Ian McEwan Ian Russell McEwan, (born 21 June 1948) is an English novelist and screenwriter. In 2008, ''The Times'' featured him on its list of "The 50 greatest British writers since 1945" and ''The Daily Telegraph'' ranked him number 19 in its list of th ...

's 2005 ''

Saturday Saturday is the day of the week between Friday and Sunday. No later than the 2nd century, the Romans named Saturday ("Saturn's Day") for the planet Saturn, which controlled the first hour of that day, according to Vettius Valens. The day's na ...

''. It was criticised as prejudiced in the medical journal ''

The Lancet ''The Lancet'' is a weekly peer-reviewed general medical journal and one of the oldest of its kind. It is also the world's highest-impact academic journal. It was founded in England in 1823. The journal publishes original research articles, ...

'' for its negative portrayal of the protagonist with the disease.

Fictional diseases

Diseases, especially if

infectious An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable dise ...

, have long been popular themes and plot devices in fiction.

Daniel Defoe Daniel Defoe (; born Daniel Foe; – 24 April 1731) was an English writer, trader, journalist, pamphleteer and spy. He is most famous for his novel ''Robinson Crusoe'', published in 1719, which is claimed to be second only to the Bible in its ...

's pioneering 1722 ''

A Journal of the Plague Year ''A Journal of the Plague Year: Being Observations or Memorials, Of the most Remarkable Occurrences, As well Publick as Private, which happened in London During the last Great Visitation In 1665'', commonly called ''A Journal of the Plague Ye ...

'' is a fictional diary of a man's life during the plague year of 1665 in England.

Mary Shelley Mary Wollstonecraft Shelley (; ; 30 August 1797 – 1 February 1851) was an English novelist who wrote the Gothic fiction, Gothic novel ''Frankenstein, Frankenstein; or, The Modern Prometheus'' (1818), which is considered an History of scie ...

's 1826 ''

The Last Man ''The Last Man'' is an apocalyptic, dystopian science fiction novel by Mary Shelley, first published in 1826. The narrative concerns Europe in the late 21st century, ravaged by a mysterious plague pandemic that rapidly sweeps across the entire ...

'' created the genre of "post-apocalyptic pandemic thriller" with her story of a plague that is spreading across Europe towards her protagonists in Britain.

Edgar Allan Poe Edgar Allan Poe (; Edgar Poe; January 19, 1809 – October 7, 1849) was an American writer, poet, editor, and literary critic. Poe is best known for his poetry and short stories, particularly his tales of mystery and the macabre. He is wide ...

's 1842 "

The Masque of the Red Death "The Masque of the Red Death" (originally published as "The Mask of the Red Death: A Fantasy") is a short story by American writer Edgar Allan Poe, first published in 1842. The story follows Prince Prospero's attempts to avoid a dangerous plague ...

" is a

gothic Gothic or Gothics may refer to: People and languages *Goths or Gothic people, the ethnonym of a group of East Germanic tribes **Gothic language, an extinct East Germanic language spoken by the Goths **Crimean Gothic, the Gothic language spoken b ...

tale of a plague, perhaps symbolising the

hubris Hubris (; ), or less frequently hybris (), describes a personality quality of extreme or excessive pride or dangerous overconfidence, often in combination with (or synonymous with) arrogance. The term ''arrogance'' comes from the Latin ', mean ...

of the wealthy, and their nemesis. More recently,

Michael Crichton John Michael Crichton (; October 23, 1942 – November 4, 2008) was an American author and filmmaker. His books have sold over 200 million copies worldwide, and over a dozen have been adapted into films. His literary works heavily feature tech ...

's 1969 ''

'' is a

science fiction Science fiction (sometimes shortened to Sci-Fi or SF) is a genre of speculative fiction which typically deals with imaginative and futuristic concepts such as advanced science and technology, space exploration, time travel, parallel unive ...

thriller about a world-threatening

microbe A microorganism, or microbe,, ''mikros'', "small") and ''organism'' from the el, ὀργανισμός, ''organismós'', "organism"). It is usually written as a single word but is sometimes hyphenated (''micro-organism''), especially in olde ...

that a

military satellite A military satellite is an artificial satellite used for a military purpose. The most common missions are intelligence gathering, navigation and military communications. The first military satellites were photographic reconnaissance missions. So ...

brings down to Earth and wipes out a town in Arizona. White-coated scientists do their best to contain the outbreak. The 1995 ''

12 Monkeys ''12 Monkeys'' is a 1995 American science fiction film directed by Terry Gilliam, inspired by Chris Marker's 1962 short film ''La Jetée'', starring Bruce Willis, Madeleine Stowe, and Brad Pitt, with Christopher Plummer and David Morse in sup ...

'' is another post-apocalyptic thriller.

References

External links

* {{Biology in fiction Biology and culture Fiction about medicine and health Dark fantasy

Real diseases

Fictional diseases

See also

References

Further reading

External links