Dimethyl-p-phenylenediamine
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Dimethyl-4-phenylenediamine is an amine. It has been used as an accelerator for the vulcanization of rubber. It can be used in
oxidase test The oxidase test is used to determine if an organism possesses the cytochrome c oxidase enzyme. The test is used as an aid for the differentiation of ''Neisseria'', ''Moraxella'', '' Campylobacter'' and ''Pasteurella'' species (oxidase positive). I ...
s.


Synthesis

Dimethyl-4-phenylenediamine is made by the nitrosylation of
dimethylaniline ''N'',''N''-Dimethylaniline (DMA) is an organic chemical compound, a substituted derivative of aniline. It consists of a tertiary amine, featuring dimethylamino group attached to a phenyl group. This oily liquid is colourless when pure, but comm ...
followed by reduction.


Applications

Dimethyl-4-phenylenediamine can be converted to
methylene blue Methylthioninium chloride, commonly called methylene blue, is a salt used as a dye and as a medication. Methylene blue is a thiazine dye. As a medication, it is mainly used to treat methemoglobinemia by converting the ferric iron in hemoglobin ...
by reaction with
dimethylaniline ''N'',''N''-Dimethylaniline (DMA) is an organic chemical compound, a substituted derivative of aniline. It consists of a tertiary amine, featuring dimethylamino group attached to a phenyl group. This oily liquid is colourless when pure, but comm ...
and sodium thiosulfate in several steps: : It is used as accelerator for the vulcanization of rubber, being first converted to the corresponding mercaptobenzothiazole. :


References

{{reflist Anilines Diamines Dimethylamino compounds