Dilip V. Jeste is an American geriatric

neuropsychiatrist Neuropsychiatry or Organic Psychiatry is a branch of medicine that deals with psychiatry as it relates to neurology, in an effort to understand and attribute behavior to the interaction of neurobiology and social psychology factors. Within neurop ...

, who specializes in successful

aging Ageing ( BE) or aging ( AE) is the process of becoming older. The term refers mainly to humans, many other animals, and fungi, whereas for example, bacteria, perennial plants and some simple animals are potentially biologically immortal. In ...

as well as

schizophrenia Schizophrenia is a mental disorder characterized by continuous or relapsing episodes of psychosis. Major symptoms include hallucinations (typically hearing voices), delusions, and disorganized thinking. Other symptoms include social withdra ...

and other

psychotic disorders Psychosis is a condition of the mind that results in difficulties determining what is real and what is not real. Symptoms may include delusions and hallucinations, among other features. Additional symptoms are incoherent speech and behavior t ...

in older adults. He was senior associate dean for healthy aging and senior care, distinguished professor of psychiatry and neurosciences, Estelle and Edgar Levi Memorial Chair in Aging, director of the Sam and Rose

Stein Institute for Research on Aging Sam and Rose Stein Institute for Research on Aging (Stein Institute for Research on Aging) is a non-profit, multidisciplinary research institute at the University of California, San Diego School of Medicine located in La Jolla, California. Estab ...

, and co-director of the IBM-UCSD Artificial Intelligence Center for Healthy Living at the

University of California, San Diego School of Medicine The University of California San Diego School of Medicine is the graduate medical school of the University of California, San Diego. It was the third medical school in the University of California system, after those established at UCSF and UCLA, ...

. after serving for 36 years, he retired from UC San Diego on July 1, 2022. He is the author, with Scott LaFee, of ''Wiser: The Scientific Roots of Wisdom, Compassion, and What Makes Us Good''. In it, he describes evidence-based findings on the definition, measurement, and neurobiology of wisdom as well as its relationship with aging, and interventions to promote wisdom. Jeste is past president of the

American Psychiatric Association The American Psychiatric Association (APA) is the main professional organization of psychiatrists and trainee psychiatrists in the United States, and the largest psychiatric organization in the world. It has more than 37,000 members are involve ...

(APA). He was the first Asian-American, to preside over this 175-year-old organization. He was also the first psychiatrist of Indian descent to be elected to the

Institute of Medicine The National Academy of Medicine (NAM), formerly called the Institute of Medicine (IoM) until 2015, is an American nonprofit, non-governmental organization. The National Academy of Medicine is a part of the National Academies of Sciences, E ...

(IOM) of the

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...

. He gave a

TEDMED TEDMED is an annual conference focusing on health and medicine, with a year-round web-based community. TEDMED is an independent event operating under license from the nonprofit TED conference. Background , TEDMED staff operates from Stamfor ...

talk on wisdom and aging in 2015. Jeste has published 14 books, more than 750 articles in peer-reviewed journals, and over 160 book chapters, and he was listed in "The Best Doctors in America", and also in the

Institute for Scientific Information The Institute for Scientific Information (ISI) was an academic publishing service, founded by Eugene Garfield in Philadelphia in 1956. ISI offered scientometric and bibliographic database services. Its specialty was citation indexing and analysis, ...

list of the "world's most cited authors", comprising less than 0.5% percent of all publishing researchers of the previous two decades. He has received numerous awards, including those from the

National Alliance on Mental Illness The National Alliance on Mental Illness (NAMI) is a United States-based nonprofit organization originally founded as a grassroots group by family members of people diagnosed with mental illness. NAMI identifies its mission as "providing advoc ...

, International Psychogeriatric Association,

National Institute of Mental Health The National Institute of Mental Health (NIMH) is one of 27 institutes and centers that make up the National Institutes of Health (NIH). The NIH, in turn, is an agency of the United States Department of Health and Human Services and is the prima ...

(NIMH), Institute of Living, Veterans Affairs, and APA.

Professional experience

Jeste obtained his medical degree in Pune, and psychiatry training at KEM hospital in

Mumbai Mumbai (, ; also known as Bombay — the official name until 1995) is the capital city of the Indian state of Maharashtra and the ''de facto'' financial centre of India. According to the United Nations, as of 2018, Mumbai is the second- ...

India India, officially the Republic of India (Hindi: ), is a country in South Asia. It is the seventh-largest country by area, the second-most populous country, and the most populous democracy in the world. Bounded by the Indian Ocean on the so ...

. After coming to the United States, he completed psychiatry residency at

Cornell University Cornell University is a private statutory land-grant research university based in Ithaca, New York. It is a member of the Ivy League. Founded in 1865 by Ezra Cornell and Andrew Dickson White, Cornell was founded with the intention to teach an ...

, and neurology residency at

George Washington University , mottoeng = "God is Our Trust" , established = , type = Private federally chartered research university , academic_affiliations = , endowment = $2.8 billion (2022) , preside ...

. He was a research fellow, and later, Chief of the Units on Movement Disorders and Dementias at the

(NIMH). In 1986 he joined

UC San Diego School of Medicine The University of California San Diego School of Medicine is the graduate medical school of the University of California, San Diego. It was the third medical school in the University of California system, after those established at UCSF and UCLA, ...

, where he developed an

NIMH NIMH may refer to: *Nickel–metal hydride battery (NiMH), a type of electrical battery *National Institute of Mental Health, an agency of the United States government *National Institute of Medical Herbalists, a professional organisation in the Un ...

-funded Geriatric Psychiatry Clinical Research Center, focused on schizophrenia and other psychoses in late life. He was editor-in-chief of ''

The American Journal of Geriatric Psychiatry ''The American Journal of Geriatric Psychiatry'' is a quarterly peer-reviewed medical journal covering geriatric psychiatry. It was established in 1993 and is published by Elsevier on behalf of the American Association for Geriatric Psychiatry. T ...

'' for 15 years, and is currently the editor-in-chief of ''International Psychogeriatrics''. Jeste's work has been cited nationally and internationally in popular media including

PBS The Public Broadcasting Service (PBS) is an American public broadcasting, public broadcaster and Non-commercial activity, non-commercial, Terrestrial television, free-to-air television network based in Arlington, Virginia. PBS is a publicly fu ...

National Public Radio National Public Radio (NPR, stylized in all lowercase) is an American privately and state funded nonprofit media organization headquartered in Washington, D.C., with its NPR West headquarters in Culver City, California. It differs from other n ...

, ''

Time Time is the continued sequence of existence and events that occurs in an apparently irreversible succession from the past, through the present, into the future. It is a component quantity of various measurements used to sequence events, to ...

'', ''

The New York Times ''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid ...

'', ''

The Atlantic ''The Atlantic'' is an American magazine and multi-platform publisher. It features articles in the fields of politics, foreign affairs, business and the economy, culture and the arts, technology, and science. It was founded in 1857 in Boston, ...

'', ''

The Times ''The Times'' is a British daily national newspaper based in London. It began in 1785 under the title ''The Daily Universal Register'', adopting its current name on 1 January 1788. ''The Times'' and its sister paper ''The Sunday Times'' (fou ...

'', ''

Los Angeles Times The ''Los Angeles Times'' (abbreviated as ''LA Times'') is a daily newspaper that started publishing in Los Angeles in 1881. Based in the LA-adjacent suburb of El Segundo since 2018, it is the sixth-largest newspaper by circulation in the Un ...

'', ''

O, The Oprah Magazine ''O, The Oprah Magazine'', also known simply as ''O'', is an American monthly magazine founded by talk show host Oprah Winfrey and Hearst Communications. Overview It was first published on April 19, 2000. , its average paid circulation was ...

'' and ''

Scientific American ''Scientific American'', informally abbreviated ''SciAm'' or sometimes ''SA'', is an American popular science magazine. Many famous scientists, including Albert Einstein and Nikola Tesla, have contributed articles to it. In print since 1845, it i ...

'', among others.

Research

Jeste's primary areas of research are

psychosis Psychosis is a condition of the mind that results in difficulties determining what is real and what is not real. Symptoms may include delusions and hallucinations, among other features. Additional symptoms are incoherent speech and behavior ...

and its treatment in late life, and successful cognitive

, including

wisdom Wisdom, sapience, or sagacity is the ability to contemplate and act using knowledge, experience, understanding, common sense and insight. Wisdom is associated with attributes such as unbiased judgment, compassion, experiential self-knowledge, ...

. He has also conducted studies of clinical, neuropsychological and neurobiological characteristics of late-onset

, aging of early-onset schizophrenia patients, and

Alzheimer's disease Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term me ...

. In terms of treatments, he has published on therapeutic and adverse effects (including

tardive dyskinesia Tardive dyskinesia (TD) is a disorder that results in involuntary repetitive body movements, which may include grimacing, sticking out the tongue or smacking the lips. Additionally, there may be rapid jerking movements or slow writhing movemen ...

and

metabolic syndrome Metabolic syndrome is a clustering of at least three of the following five medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein (HDL). Metabolic syndrome ...

) of

antipsychotics Antipsychotics, also known as neuroleptics, are a class of Psychiatric medication, psychotropic medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia but ...

. He also has published on psychosocial treatments as well as certain bioethical aspects of research (particularly decision making capacity and methods for enhancing it) among older people with

psychotic Psychosis is a condition of the mind that results in difficulties determining what is real and what is not real. Symptoms may include delusions and hallucinations, among other features. Additional symptoms are incoherent speech and behavior ...

disorders.

Personal life

Jeste was born in a small town in the state of

Maharashtra Maharashtra (; , abbr. MH or Maha) is a states and union territories of India, state in the western India, western peninsular region of India occupying a substantial portion of the Deccan Plateau. Maharashtra is the List of states and union te ...

, and became the first medical doctor in his family. He and his wife, Sonali Jeste, M.D. (who later became a child psychiatrist), immigrated to the U.S. in 1974 to pursue further training. They live in

San Diego San Diego ( , ; ) is a city on the Pacific Ocean coast of Southern California located immediately adjacent to the Mexico–United States border. With a 2020 population of 1,386,932, it is the List of United States cities by population, eigh ...

California California is a U.S. state, state in the Western United States, located along the West Coast of the United States, Pacific Coast. With nearly 39.2million residents across a total area of approximately , it is the List of states and territori ...

, and have two daughters.

Selected books

*Jeste DV and Wyatt RJ: ''Understanding and Treating Tardive Dyskinesia''. New York: Guilford Press Inc. 1982 (363 pages). *Mueser KT and Jeste DV (eds): ''Clinical Handbook of Schizophrenia''. New York: Guilford Press, 2008 (650 pages). *Depp CA and Jeste DV (eds): ''Successful Cognitive and Emotional Aging''. Washington, DC: American Psychiatric Press, Inc., 2009 (419 pages). *Jeste DV and Bell CC (eds): ''Prevention in Mental Health: Lifespan Perspective. Psychiatric Clinics of North America''. W. B. Sunders Company, a Division of Elsevier Inc., Philadelphia, PA, 2011 (274 pages). *Dilip V. Jeste, MD, and Barton W. Palmer, PhD, Eds. (2015): ''Positive Psychiatry: A Clinical Handbook''. Arlington, VA: American Psychiatric Publishing. *Dilip V. Jeste, MD, with Scott LaFee: ''Wiser: The Scientific Roots of Wisdom''. New York, NY: Sounds True. 2020

Selected articles

*Jeste DV, Potkin SG, Sinha S, Feder SL and Wyatt RJ: "Tardive dyskinesia reversible and persistent" ''Archives of General Psychiatry'' 36:585 590, 1979. *Jeste DV, Gillin JC and Wyatt RJ: "Serendipity in biological psychiatry A myth?" ''Archives of General Psychiatry'' 36:1173 1178, 1979. *Jeste DV and Wyatt RJ: "Changing epidemiology of tardive dyskinesia An overview" ''American Journal of Psychiatry'' 138:297 309, 1981. *Jeste DV, Kleinman JE, Potkin SG, Luchins DJ and Weinberger DR: "Ex uno multi: Subtyping the schizophrenia syndrome. (Recipient of the A.E. Bennett Research Award for 1981) ''Biological Psychiatry'' 17:199 222, 1982. *Harris MJ and Jeste DV: "Late onset schizophrenia: An overview" ''Schizophrenia Bulletin'' 14:39-55, 1988. *Jeste DV and Lohr JB: "Hippocampal pathologic findings in schizophrenia: A morphometric study" ''Archives of General Psychiatry'' 46:1019-1024, 1989. *Jeste DV, Lohr JB and Manley M: "Study of neuropathologic changes in the striatum following four, eight and twelve months of treatment with fluphenazine in rats" ''Psychopharmacology'' 106:154-160, 1992. *Gilbert PL, Harris MJ, McAdams LA and Jeste DV: "Neuroleptic withdrawal in schizophrenic patients: A review of the literature" ''Archives of General Psychiatry'' 52:173-188, 1995. *Jeste DV, Caligiuri MP, Paulsen JS, Heaton RK, Lacro JP, Harris MJ, Bailey A, Fell RL and McAdams LA: "Risk of tardive dyskinesia in older patients: A prospective longitudinal study of 266 outpatients" ''Archives of General Psychiatry'' 52:756-765, 1995. *Cuffel BJ, Jeste DV, Patterson TL, Halpain M, Pratt C: "Treatment costs and use of community mental health services for schizophrenia by age-cohorts" ''American Journal of Psychiatry'' 153(7): 870–876, 1996. *Palmer BW, Heaton RK, Paulsen JS, Kuck J, Braff D, Harris MJ, Zisook S and Jeste DV: "Is it possible to be schizophrenic yet neuropsychologically normal?" ''Neuropsychology'' 11(3):437-446, 1997. *Jeste DV, Symonds LL, Harris MJ, Paulsen JS, Palmer BW and Heaton RK: "Non-dementia non-praecox dementia praecox?: Late-onset schizophrenia". ''The American Journal of Geriatric Psychiatry'' 5(4):302-317, 1997. *Jeste DV, Lohr JB, Eastham JH, Rockwell E and Caligiuri MP: "Adverse effects of long-term use of neuroleptics: Human and animal studies". ''Journal of Psychiatry Research'' 32:201-214, 1998. *Jeste DV, Alexopoulos GS, Bartels SJ, Cummings JL, Gallo JJ, Gottlieb GL, Halpain MC, Palmer BW, Patterson TL, Reynolds CF and Lebowitz BD: "Consensus statement on the upcoming crisis in geriatric mental health: Research agenda for the next two decades" ''Archives of General Psychiatry'' 56:848-853, 1999. *Jeste DV and Finkel SI: "Psychosis of Alzheimer's disease and related dementias: Diagnostic criteria for a distinct syndrome". ''The American Journal of Geriatric Psychiatry'' 8: 29–34, 2000. *Howard R, Rabins P, Seeman MV, Jeste DV and the International Late-Onset Schizophrenia Group: "Late-onset schizophrenia and very-late-onset schizophrenia-like psychosis: An international consensus" ''American Journal of Psychiatry'' 157:172-178, 2000. *Heaton RK, Gladsjo JA, Palmer BW, Kuck J, Marcotte TD and Jeste DV: "Stability and course of neuropsychological deficits in schizophrenia" ''Archives of General Psychiatry'' 58:24-32, 2001. *Patterson TL, Goldman S, McKibbin CL, Hughs T and Jeste DV: "UCSD Performance-Based Skills Assessment: Development of a new measure of everyday functioning for severely mentally ill adults" ''Schizophrenia Bulletin'' 27(2): 235–245, 2001 *Depp CA and Jeste DV: "Bipolar disorder in older adults: A critical review". ''Bipolar Disorders'' 6: 343–367, 2004. *Folsom DP, Hawthorne W, Lindamer L, Gilmer T, Bailey A, Golshan S, Garcia P, Unutzer J, Hough R and Jeste DV: "Prevalence and risk factors for homelessness and utilization of mental health services among 10,340 patients with serious mental illness in a large public mental health system" ''American Journal of Psychiatry'' 162: 370–376, 2005. *Depp C and Jeste DV: "Definitions and predictors of successful aging: A comprehensive review of the literature". ''The American Journal of Geriatric Psychiatry'' 14:6-20, 2006. *Patterson TL, McKibbin C, Mausbach BT, Goldman S, Bucardo J and Jeste DV: "Functional Adaptation Skills Training (FAST): A randomized trial of a psychosocial intervention for middle-aged and older patients with chronic psychotic disorders". ''Schizophrenia Research'' 86:291-299, 2006. *Jeste DV, Halpain M, Trinidad G, Reichstadt J, and Lebowitz BD: "UCSD's short-term research training programs for trainees at different levels of career development". ''Academic Psychiatry'' 31:160-167, 2007. *Jeste DV, Palmer BW, Appelbaum PS, Golshan S, Glorioso D, Dunn LB, Kim K, Meeks T, Kraemer HC: "A new brief instrument for assessing decisional capacity for clinical research" ''Archives of General Psychiatry'' 64:966-974, 2007. *Folsom DP, Gilmer T, Barrio C, Moore DJ, Bucardo J, Lindamer LA, Garcia P, Hawthorne W, Hough R, Patterson T, and Jeste DV: "A longitudinal study of the use of mental health services by persons with serious mental illness: Spanish-speaking Latinos differ from English-speaking Latinos and Caucasians" ''American Journal of Psychiatry'' 164:1173-1180, 2007. *Granholm E, McQuaid JR, McClure FS, Link P, Perivoliotis D, Gottlieb JD, Patterson T and Jeste DV: "Randomized controlled trial of cognitive behavioral social skills training for older people with schizophrenia: 12-month follow-up" ''Journal of Clinical Psychiatry'' 68:730-7, 2007. *Jeste DV, Blazer D, Casey DE, Meeks T, Salzman C, Schneider L, Tariot P and Yaffe K: "ACNP White Paper: Update on the use of antipsychotic drugs in elderly persons with dementia" ''Neuropsychopharmacology'' 33:957-970, 2008. *Jeste DV and Vahia I: "Comparison of the conceptualization of wisdom in ancient Indian literature with modern views: Focus on the Bhagavad Gita". ''Psychiatry'' 71:197-209, 2008. *Meeks TW and Jeste DV: "Neurobiology of wisdom: An overview" ''Archives of General Psychiatry'' 66:355-365, 2009. *Jeste DV, Palmer BW, Golshan S, Eyler LT, Dunn LB, Meeks T, Glorioso D, Fellows I, Kraemer H and Appelbaum PS: "Multimedia consent for research in people with schizophrenia and normal subjects: A randomized controlled trial" ''Schizophrenia Bulletin'' 35:719-29, 2009. *Jeste DV and Harris JC: "Commentary: Wisdom - A neuroscience perspective" ''Journal of the American Medical Association'' 304:1602-1603, 2010. *Soontornniyomkij V, Risbrough VB, Young JW, Wallace CK, Soontornniyomkij B, Jeste DV and Achim CL: "Short-term recognition memory impairment is associated with decreased expression of FK506 binding protein 51 in the aged mouse brain". ''Age'' 32:309-322, 2010. *Jeste DV, Wolkowitz OM and Palmer BW: "Divergent trajectories of physical, cognitive, and psychosocial aging in schizophrenia" ''Schizophrenia Bulletin'' 37:451-455, 2011. *Jeste DV: "Promoting successful ageing through integrated care" ''British Medical Journal'' 2011; 343: d6808. *Jeste DV: "Mental health and the 2012 US election". ''The Lancet'', 6 October 2012, Vol. 380, Issue 9849, Pages 1206–1208. *Lee EE, Liu J, Tu X, Palmer BW, Eyler LT, Jeste DV: "A Widening Longevity Gap between People with Schizophrenia and General Population: A Literature Review and Call for Action". Special Issue. ''Schizophrenia Research'' *Jeste DV, Palmer BW, Rettew DC, Boardman S. "Positive psychiatry: its time has come". ''Journal of Clinical Psychiatry'' 76:675-83, 2015. *Lewis-Fernández R, Rotheram-Borus MJ, Betts VT, Greenman L, Essock SM, Brent D, Escobar JI, Barch D, Hogan MF, Areán PA, Druss BG, DiClemente RJ, McGlashan TH, Jeste DV, Proctor EK, Ruiz P, Rush AJ, Canino GJ, Bell CC, Henry R, Iversen P: "Rethinking funding priorities in mental health research". ''British Journal of Psychiatry''. 2016 Jun;208(6):507-9. *Jeste DV, Palmer BW: "Mild Neurocognitive Disorder: A Model for Accelerated Biological Aging?" ''American Journal Geriatric Psychiatry''. 2016 Nov;24(11):987-988. *Jeste DV, Blazer II DG, Buckwalter KC, Cassidy KL, Fishman L, Gwyther LP, Levin S, Liu K, JLustig T, Phillipson C, Rao R, Rosenbloom S, Schmeding E, Vega W, Avanzino JA, Glorioso DK, Feather, J: "Age-Friendly Communities Initiative: Public Health Approach to Promoting Successful Aging". ''American Journal Geriatric Psychiatry''. 2016 Dec;24(12):1158-1170. *Jeste DV, Avanzino J, Depp CA, Gawronska M, Tu X, Sewell DD, Huege SF: "Effect of Short-Term Research Training Programs on Medical Students' Attitudes Toward Aging". ''Gerontology & Geriatrics Education'', DOI: 10.1080/02701960.2017.1340884. 2017 Jun 14:1-9. *Jeste DV, Palmer BW, Saks ER: "Why We Need Positive Psychiatry for Schizophrenia and Other Psychotic Disorders". ''Schizophrenia Bulletin''. 2017 Mar 1;43(2):227-229 *Thomas ML, Bangen K, Palmer BW, Martin AS, Avanzino JA, Glorioso DK, Daly RE, Jeste, DV: "A New Scale for Assessing Wisdom Based on Common Domains and a Neurobiological Model: The San Diego Wisdom Scale (SD-WISE)". ''Journal of Psychiatric Research''

References

External links

Center for Healthy Aging
at the

Division of Geriatric Psychiatry

* {{DEFAULTSORT:Jeste, Dilip Living people American psychiatrists University of California, San Diego faculty Year of birth missing (living people) Members of the National Academy of Medicine American medical writers