Diane J. Mathis is the Morton Grove-Rasmussen chair of

immunohematology Immunohematology is a branch of hematology and transfusion medicine which studies antigen-antibody reactions and analogous phenomena as they relate to the pathogenesis and clinical manifestations of blood disorders. A person employed in this field ...

Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...

. She has been recognized for her research with elections to the

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...

and

American Academy of Arts and Sciences The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and ...

Education

Mathis received her BS from

Wake Forest University Wake Forest University is a private research university in Winston-Salem, North Carolina. Founded in 1834, the university received its name from its original location in Wake Forest, north of Raleigh, North Carolina. The Reynolda Campus, the un ...

and her PhD from the

University of Rochester The University of Rochester (U of R, UR, or U of Rochester) is a private research university in Rochester, New York. The university grants undergraduate and graduate degrees, including doctoral and professional degrees. The University of Roc ...

. She did postdoctoral research at the Laboratoire de Génétique Moléculaire des Eucaryotes in

Strasbourg, France Strasbourg (, , ; german: Straßburg ; gsw, label=Bas Rhin Alsatian dialect, Alsatian, Strossburi , gsw, label=Haut Rhin Alsatian dialect, Alsatian, Strossburig ) is the Prefectures in France, prefecture and largest city of the Grand Est Re ...

, and at

Stanford University Medical Center Stanford University Medical Center is a medical complex which includes Stanford Health Care and Stanford Children's Health. It is consistently ranked as one of the best hospitals in the United States and serves as a teaching hospital for the ...

Career

Mathis returned to the Institut de Genetique et de Biologie Moleculaire et Cellulaire in France, and established a lab in collaboration with Christophe Benoist. Mathis and Benoist moved their lab to the

Joslin Diabetes Center Joslin Diabetes Center is the world's largest diabetes research center, diabetes clinic, and provider of diabetes education. It is located in the Longwood Medical and Academic Area in Boston, Massachusetts, United States. Among the Harvard Medica ...

in Boston in 1999. In 2009, she joined the department of

pathology Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in ...

at Harvard Medical School, where she and Benoist continue to operate a joint lab. She is currently the Morton Grove-Rasmussen chair of

there, and an associate member of the

Broad Institute The Eli and Edythe L. Broad Institute of MIT and Harvard (IPA: , pronunciation respelling: ), often referred to as the Broad Institute, is a biomedical and genomic research center located in Cambridge, Massachusetts, Cambridge, Massachusetts, U ...

. Her research focuses on

T cell A T cell is a type of lymphocyte. T cells are one of the important white blood cells of the immune system and play a central role in the adaptive immune response. T cells can be distinguished from other lymphocytes by the presence of a T-cell r ...

tolerance and autoimmunity, particularly as it applies to the development of

type I diabetes Type 1 diabetes (T1D), formerly known as juvenile diabetes, is an autoimmune disease that originates when cells that make insulin (beta cells) are destroyed by the immune system. Insulin is a hormone required for the cells to use blood sugar for ...

. Mathis was elected to the

in 2003 and the

in 2012. Columbia University recognized her contributions to the understanding of type I diabetes with the 2012 Naomi Berrie Award. In 2017, she received the

FASEB Excellence in Science Award The Excellence in Science Award was established by the Federation of American Societies for Experimental Biology (FASEB) in 1989 to recognize outstanding achievement by women in biological science. All women who are members of one or more of the so ...

. * Rabbi Shai Shaknai Award (2018)

References

Members of the United States National Academy of Sciences Fellows of the American Academy of Arts and Sciences Harvard Medical School faculty University of Rochester alumni Wake Forest University alumni American immunologists Living people Year of birth missing (living people) {{DEFAULTSORT:Mathis, Diane