HOME

TheInfoList



OR:

Diafiltration is a dilution process that involves removal or separation of components (permeable molecules like
salts In chemistry, a salt is a chemical compound consisting of an ionic assembly of positively charged cations and negatively charged anions, which results in a compound with no net electric charge. A common example is table salt, with positively cha ...
, small
protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
s,
solvent A solvent (s) (from the Latin '' solvō'', "loosen, untie, solve") is a substance that dissolves a solute, resulting in a solution. A solvent is usually a liquid but can also be a solid, a gas, or a supercritical fluid. Water is a solvent for ...
s etc.,) of a
solution Solution may refer to: * Solution (chemistry), a mixture where one substance is dissolved in another * Solution (equation), in mathematics ** Numerical solution, in numerical analysis, approximate solutions within specified error bounds * Soluti ...
based on their
molecular size A molecule is a group of two or more atoms held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions which satisfy this criterion. In quantum physics, organic chemistry, and bioch ...
by using micro-molecule permeable filters in order to obtain pure solution.


References


Further reading

* * *{{cite journal , last1 = Sheth , first1 = Jignesh P. , display-authors=et al , year = 2003 , title = Nanofiltration-based diafiltration process for solvent exchange in pharmaceutical manufacturing , journal = Journal of Membrane Science , volume = 211 , issue = 2, pages = 251–261 , doi=10.1016/s0376-7388(02)00423-4


External links


Diafiltration for Desalting or Buffer Exchange

Mobius Ultra/ Diafiltration Solutions
Membrane technology