Deschutes River may refer to:
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Deschutes River (Oregon)
The Deschutes River in central Oregon is a major tributary of the Columbia River. The river provides much of the drainage on the eastern side of the Cascade Range in Oregon, gathering many of the tributaries that descend from the drier, eastern ...
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Little Deschutes River (Oregon), a tributary of the Deschutes River in Oregon
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Deschutes River (Washington)
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River De Chute in Maine
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