The Department of Biochemistry of

Oxford University The University of Oxford is a collegiate research university in Oxford, England. There is evidence of teaching as early as 1096, making it the oldest university in the English-speaking world and the second-oldest continuously operating u ...

is located in the Science Area in

Oxford Oxford () is a City status in the United Kingdom, cathedral city and non-metropolitan district in Oxfordshire, England, of which it is the county town. The city is home to the University of Oxford, the List of oldest universities in continuou ...

, England. It is one of the largest biochemistry departments in Europe. The Biochemistry Department is part of the University of Oxford's Medical Sciences Division, the largest of the university's four academic divisions, which has been ranked first in the world for biomedicine.

History

The Department of Biochemistry at Oxford University began as the

physiological chemistry Biochemistry, or biological chemistry, is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology, a ...

section of the Physiology Department, and acquired its own separate department and building in the 1920s. In 1920, Benjamin Moore was elected to the position of the Whitley Professor of Biochemistry, the newly established Chair of Biochemistry at Oxford University. He was followed by

Rudolph Peters Sir Rudolph Albert Peters MC MID FRS HFRSE FRCP LLD (13 April 1889 – 29 January 1982) was a British biochemist. He led the research team at Oxford who developed British Anti-Lewisite (BAL), an antidote for the chemical warfare agent lewisite. ...

in 1923, and an endowment of £75,000 was soon granted by the

Rockefeller Foundation The Rockefeller Foundation is an American private foundation and philanthropic medical research and arts funding organization based at 420 Fifth Avenue, New York City. The foundation was created by Standard Oil magnate John D. Rockefeller (" ...

for the construction of a new departmental building, purchase of equipment, and its maintenance. The Biochemistry Department building opened in 1927. In 1954, Hans Krebs was appointed the Whitley Chair of Biochemistry, and his appointment brought greater prominence to the department. He brought with him the Medical Research Council unit established to conduct research on cell metabolism. In 1955, a second professorship in the department, the Iveagh Chair of Microbiology, was established with funding from Guinness and the sub-department of Microbiology created, with Donald Woods its first holder. The eight-storey Hans Krebs Building was constructed in 1964 with funds from the Rockefeller Foundation. Krebs was succeeded by Rodney Porter in 1967. Genetics was brought into the Biochemistry Department when

Walter Bodmer Sir Walter Fred Bodmer (born 10 January 1936) is a German-born British human geneticist. Early life Bodmer was born in Frankfurt, Germany. He was educated at Manchester Grammar School and went on to study the Mathematical Tripos at the Univ ...

was appointed the first Professor of Genetics in 1970. The Laboratory of Molecular Biophysics, first established in the Zoology Department with support from Krebs and also linked to the

Physical Chemistry Laboratory The Physical and Theoretical Chemistry Laboratory (PTCL) is a major chemistry laboratory at the University of Oxford, England. It is located in the main Science Area of the university on South Parks Road. Previously it was known as the Physica ...

of the Chemistry Department, became part of the Biochemistry Department. It moved into the Rex Richards building built in 1984, with David Phillips the Professor in Molecular Biophysics. The Oxford Glycobiology Institute, headed by

Raymond Dwek Raymond Allen Dwek Order of the British Empire, CBE Fellow of the Royal Society, FRS Fellow of the Royal Society of Chemistry, FRSC (born 10 November 1941) is a scientist at the University of Oxford and co-founder of the biotechnology company Ox ...

and housed in the Rodney Porter Building, opened in 1991. The department is now part of the Medical Sciences Division of Oxford University, under the Divisional Boards formed in 2000. In 2006, two older biochemistry buildings were demolished, followed by two more including the Han Krebs Tower in 2014, to make way for the two-phase construction of the New Biochemistry Building. Francis Barr, the EP Abraham Professor of Mechanistic Cell Biology, is the head of the Biochemistry Department, replacing Mark Sansom, the David Phillips Professor in Molecular Biophysics, in January 2019.

Research

The department is sub-divided into the following research areas: *Cell Biology, Development and Genetics *Chromosomal and RNA Biology *Infection and Disease Processes *Microbiology and Systems Biology *Structural Biology and Molecular Biophysics

Academic staff

There are around 400 research staff, with about 50 independent principal investigators who lead research groups that may range from a few people to forty or more. Members of other departments also contribute to teaching, including lecturers in physiology, pathology, pharmacology, clinical biochemistry and zoology. The department hosts the Oxford University Biochemical Society, a graduate student association that invites speakers to the University of Oxford. The head of department is Professor Francis Barr. Other members of the academic staff include

Judy Armitage Judith Patricia Armitage (born 1951) is a British molecular and cellular biochemist at the University of Oxford. Early life and education Armitage was born on 21 February 1951 in Shelley, Yorkshire, England. She attended Selby Girls' High ...

Elspeth Garman Elspeth Frances Garman is a retired professor of molecular biophysics at the University of Oxford and a former President of the British Crystallographic Association. Until 2021 she was also Senior Kurti Research Fellow at Brasenose College, Oxfor ...

Jonathan Hodgkin Jonathan Alan Hodgkin (born 1949) is a British biochemist. He is the Professor of Genetics at the University of Oxford and an emeritus fellow of Keble College, Oxford. Education Hodgkin was educated at the University of Oxford where he graduat ...

Kim Nasmyth Kim Ashley Nasmyth (born 18 October 1952) is an English geneticist, the Whitley Professor of Biochemistry at the University of Oxford, a Fellow of Trinity College, Oxford, former scientific director of the Research Institute of Molecular Pathol ...

Neil Brockdorff Neil Alexander Steven Brockdorff (born 1958) is a British biochemist who is a Wellcome Trust Principal Research Fellow and professor in the department of biochemistry at the University of Oxford. Brockdorff's research investigates gene and genom ...

Rob Klose Rob Klose (born December 28, 1977) is a Canadian researcher and Professor of Genetics at the Department of Biochemistry, University of Oxford. His research investigates how chromatin-based and epigenetic mechanisms contribute to the ways in which ...

and

Alison Woollard Alison Woollard (born 1968) is a British biologist. She is a lecturer in the Department of Biochemistry at the University of Oxford where she is also a Fellow of Hertford College, Oxford. Early life and education Woollard was born in 1968 in K ...

Buildings

The department currently has two main buildings: * The

Dorothy Crowfoot Hodgkin Dorothy Mary Crowfoot Hodgkin (née Crowfoot; 12 May 1910 – 29 July 1994) was a Nobel Prize-winning English chemist who advanced the technique of X-ray crystallography to determine the structure of biomolecules, which became essential for ...

building * The Rex Richards building (housing the NMR facility in the basement) Until 2006, two older buildings housing

genetics Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinians, Augustinian ...

(the

building) and biochemistry (the

building) were also part of the department. However, these were demolished in 2006 to make way for the first phase of the construction of the New Biochemistry building, completed in October 2008. Until 2008 biochemistry also occupied the Donald Woods building and the Hans Krebs Tower, which were demolished in 2014 for the second phase of the construction. The New Biochemistry building was renamed Dorothy Crowfoot Hodgkin building in 2022. Until 2022 biochemistry also occupied the Rodney Porter building (Oxford

Glycobiology Defined in the narrowest sense, glycobiology is the study of the structure, biosynthesis, and biology of saccharides (sugar chains or glycans) that are widely distributed in nature. Sugars or saccharides are essential components of all living thin ...

Institute). The New Biochemistry building houses interdisciplinary research in the biosciences, including physiology, chemistry, biochemistry, and clinical neurosciences. The department moved into the purpose-built new biochemistry building during the autumn of 2008 which was designed to promote interaction and collaboration as well as provide facilities for all staff. The New Biochemistry building houses a substantial amount of contemporary art. ;Former departmental buildings Image:Hans Krebs Building, Oxford.jpg, Hans Krebs Tower, demolished 2014 Image:Walter Bodmer Building, Oxford.jpg, Walter Bodmer Building, demolished 2006 Image:Biochemistry Department, looking towards South Parks Road 2006.jpg, Donald Woods Building to the right, demolished 2014

References

Biochemistry Biochemistry, or biological chemistry, is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology, a ...

Research institutes in Oxford

History

Research

Academic staff

Buildings

References

External links