A deodorant is a substance applied to the body to prevent or mask
body odor
Body odor or body odour (BO) is present in all animals and its intensity can be influenced by many factors (behavioral patterns, survival strategies). Body odor has a strong genetic basis, but can also be strongly influenced by various diseases ...
due to bacterial breakdown of
perspiration
Perspiration, also known as sweating, is the production of fluids secreted by the sweat glands in the skin of mammals.
Two types of sweat glands can be found in humans: eccrine glands and apocrine glands. The eccrine sweat glands are distrib ...
or
vaginal secretions
Vaginal lubrication is a naturally produced fluid that lubricates a
vagina. Vaginal lubrication is always present, but production increases significantly near ovulation and during sexual arousal in anticipation of sexual intercourse. Vaginal ...
, for example in the
armpit
The axilla (also, armpit, underarm or oxter) is the area on the human body directly under the shoulder joint. It includes the axillary space, an anatomical space within the shoulder girdle between the arm and the thoracic cage, bounded superior ...
s,
groin
In human anatomy, the groin (the adjective is ''inguinal'', as in inguinal canal) is the junctional area (also known as the inguinal region) between the abdomen and the thigh on either side of the pubic bone. This is also known as the medial comp ...
, or
feet
The foot ( : feet) is an anatomical structure found in many vertebrates. It is the terminal portion of a limb which bears weight and allows locomotion. In many animals with feet, the foot is a separate organ at the terminal part of the leg made ...
. A subclass of deodorants, called antiperspirants, prevents sweating itself, typically by blocking
sweat glands. Antiperspirants are used on a wider range of body parts, at any place where sweat would be inconvenient or unsafe, since unwanted sweating can interfere with comfort,
vision
Vision, Visions, or The Vision may refer to:
Perception Optical perception
* Visual perception, the sense of sight
* Visual system, the physical mechanism of eyesight
* Computer vision, a field dealing with how computers can be made to gain un ...
, and grip (due to slipping). Other types of deodorant allow sweating but prevent
bacteria
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among ...
l action on sweat, since human sweat only has a noticeable smell when it is decomposed by bacteria.
In the United States, the
Food and Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respon ...
classifies and regulates most deodorants as
cosmetics
Cosmetics are constituted mixtures of chemical compounds derived from either natural sources, or synthetically created ones. Cosmetics have various purposes. Those designed for personal care and skin care can be used to cleanse or protect ...
, but classifies antiperspirants as
over-the-counter drug
Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a requirement for a prescription from a healthcare professional, as opposed to prescription drugs
A prescription drug (also prescription medication or prescripti ...
s.
The first commercial deodorant,
Mum, was introduced and patented in the late nineteenth century by an
inventor
An invention is a unique or novel device, method, composition, idea or process. An invention may be an improvement upon a machine, product, or process for increasing efficiency or lowering cost. It may also be an entirely new concept. If an ...
in
Philadelphia
Philadelphia, often called Philly, is the largest city in the Commonwealth of Pennsylvania, the sixth-largest city in the U.S., the second-largest city in both the Northeast megalopolis and Mid-Atlantic regions after New York City. Sinc ...
,
Pennsylvania
Pennsylvania (; ( Pennsylvania Dutch: )), officially the Commonwealth of Pennsylvania, is a state spanning the Mid-Atlantic, Northeastern, Appalachian, and Great Lakes regions of the United States. It borders Delaware to its southeast, ...
,
Edna Murphey.
The product was briefly withdrawn from the market in the US.
The modern formulation of the antiperspirant was
patent
A patent is a type of intellectual property that gives its owner the legal right to exclude others from making, using, or selling an invention for a limited period of time in exchange for publishing an enabling disclosure of the invention."A p ...
ed by
Jules Montenier on January 28, 1941.
This formulation was first found in "Stopette" deodorant spray, which ''
Time
Time is the continued sequence of existence and events that occurs in an apparently irreversible succession from the past, through the present, into the future. It is a component quantity of various measurements used to sequence events, to ...
'' magazine called "the best-selling deodorant of the early 1950s".
Use of deodorant with aluminium compounds has been suspected of being linked to breast cancer, but research has not proven any such link.
[
]
Overview
The human body produces perspiration
Perspiration, also known as sweating, is the production of fluids secreted by the sweat glands in the skin of mammals.
Two types of sweat glands can be found in humans: eccrine glands and apocrine glands. The eccrine sweat glands are distrib ...
(sweat) via two types of sweat gland: eccrine sweat glands which cover much of the skin
Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation.
Other cuticle, animal coverings, such as the arthropod exoskeleton, have diffe ...
and produce watery odourless sweat, and apocrine sweat glands in the armpit
The axilla (also, armpit, underarm or oxter) is the area on the human body directly under the shoulder joint. It includes the axillary space, an anatomical space within the shoulder girdle between the arm and the thoracic cage, bounded superior ...
s and groin
In human anatomy, the groin (the adjective is ''inguinal'', as in inguinal canal) is the junctional area (also known as the inguinal region) between the abdomen and the thigh on either side of the pubic bone. This is also known as the medial comp ...
, which produce a more oily "heavy" sweat containing a proportion of waste protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
s, fatty acid
In chemistry, particularly in biochemistry, a fatty acid is a carboxylic acid with an aliphatic chain, which is either saturated or unsaturated. Most naturally occurring fatty acids have an unbranched chain of an even number of carbon atoms, fr ...
s and carbohydrate
In organic chemistry, a carbohydrate () is a biomolecule consisting of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with a hydrogen–oxygen atom ratio of 2:1 (as in water) and thus with the empirical formula (where ''m'' may or ma ...
s, that can be metabolized
Metabolism (, from el, μεταβολή ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cell ...
by bacteria to produce compounds that cause body odor
Body odor or body odour (BO) is present in all animals and its intensity can be influenced by many factors (behavioral patterns, survival strategies). Body odor has a strong genetic basis, but can also be strongly influenced by various diseases ...
. In addition the vagina
In mammals, the vagina is the elastic, muscular part of the female genital tract. In humans, it extends from the vestibule to the cervix. The outer vaginal opening is normally partly covered by a thin layer of mucosal tissue called the hymen ...
produces secretions 440px
Secretion is the movement of material from one point to another, such as a secreted chemical substance from a cell or gland. In contrast, excretion is the removal of certain substances or waste products from a cell or organism. The classica ...
which are not a form of sweat but may be undesired and also masked with deodorants.
Human perspiration of all types is largely odorless until its organic components are fermented
Fermentation is a metabolic process that produces chemical changes in organic substrates through the action of enzymes. In biochemistry, it is narrowly defined as the extraction of energy from carbohydrates in the absence of oxygen. In food ...
by bacteria
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among ...
that thrive in hot, humid environments. The human underarm is among the most consistently warm areas on the surface of the human body, and sweat glands readily provide moisture containing a fraction of organic matter, which when excreted, has a vital cooling effect. When adult armpits are washed with alkaline
In chemistry, an alkali (; from ar, القلوي, al-qaly, lit=ashes of the saltwort) is a base (chemistry), basic, ionic compound, ionic salt (chemistry), salt of an alkali metal or an alkaline earth metal. An alkali can also be defined as ...
pH soap, the skin loses its protective acid mantle The acid mantle is a very fine, slightly acidic film on the surface of human skin acting as a barrier to bacteria, viruses and other potential contaminants that might penetrate the skin. Sebum is secreted by the sebaceous gland and when mixed wit ...
(pH 4.5–6), raising the skin pH and disrupting the skin barrier. Many bacteria are adapted to the slightly alkaline environment within the human body, so they can thrive within this elevated pH environment. This makes the skin more than usually susceptible to bacterial colonization. Bacteria on the skin feed on the waste proteins and fatty acids in the sweat from the apocrine glands
Apocrine () glands are a type of exocrine gland, which are themselves a type of gland, i.e. a group of cells specialized for the release of secretions. Exocrine glands secrete by one of three means: holocrine, merocrine and apocrine. In apocri ...
and on dead skin and hair cells, releasing trans-3-methyl-2-hexenoic acid in their waste, which is the primary cause of body odor.
Underarm hair
Underarm hair, also known as axillary hair, is the hair in the underarm area (''axilla'').
Development
Underarm or axillary hair goes through four stages of development, driven by weak androgens produced by the adrenal in males and females du ...
wicks the moisture away from the skin and aids in keeping the skin dry enough to prevent or diminish bacterial colonization. The hair is less susceptible to bacterial growth and therefore reduces bacterial odor. The apocrine sweat glands are inactive until puberty
Puberty is the process of physical changes through which a child's body matures into an adult body capable of sexual reproduction. It is initiated by hormonal signals from the brain to the gonads: the ovaries in a girl, the testes in a boy. ...
, which is why body odor often only becomes noticeable at that time.
Deodorant products work in one of two ways – by preventing sweat from occurring, or by allowing it to occur but preventing bacterial activity that decomposes sweat on the skin.
History
Modern deodorants
In 1888, the first modern commercial deodorant, Mum, was developed and patented by a U.S. inventor
An invention is a unique or novel device, method, composition, idea or process. An invention may be an improvement upon a machine, product, or process for increasing efficiency or lowering cost. It may also be an entirely new concept. If an ...
in Philadelphia
Philadelphia, often called Philly, is the largest city in the Commonwealth of Pennsylvania, the sixth-largest city in the U.S., the second-largest city in both the Northeast megalopolis and Mid-Atlantic regions after New York City. Sinc ...
, Pennsylvania
Pennsylvania (; ( Pennsylvania Dutch: )), officially the Commonwealth of Pennsylvania, is a state spanning the Mid-Atlantic, Northeastern, Appalachian, and Great Lakes regions of the United States. It borders Delaware to its southeast, ...
, Edna Murphey. The small company was bought by Bristol-Myers
The Bristol Myers Squibb Company (BMS) is an American multinational pharmaceutical company. Headquartered in New York City, BMS is one of the world's largest pharmaceutical companies and consistently ranks on the ''Fortune'' 500 list of the lar ...
in 1931 and in the late 1940s, Helen Barnett Diserens developed an underarm applicator based on the newly invented ball-point pen. In 1952, the company began marketing the product under the name Ban Roll-On. The product was briefly withdrawn from the market in the U.S., but it is once again available at retailers in the U.S. under the brand Ban. In the UK it is sold under the names Mum Solid and Mum Pump Spray. Chattem
Chattem, Inc. is an American, Chattanooga, Tennessee-based, producer and marketer of over-the-counter healthcare products, toiletries, dietary supplements, topical analgesics, and medicated skin care products. Originally named the Chattanooga Me ...
acquired Ban deodorant brand in 1998 and subsequently sold it to Kao Corporation
is a chemical and cosmetics company headquartered in Nihonbashi-Kayabacho, Chūō, Tokyo, Japan.
History
Kao was established in 1887 by Tomiro Nagase as a manufacturer of domestic toiletry soap. Until 1954, they were known as , and finally ...
in 2000.
In 1903, the first commercial antiperspirant was Everdry. The modern formulation of the antiperspirant was patented by Jules Montenier on January 28, 1941. This patent addressed the problem of the excessive acidity of aluminum chloride and its excessive irritation of the skin, by combining it with a soluble nitrile
In organic chemistry, a nitrile is any organic compound that has a functional group. The prefix ''cyano-'' is used interchangeably with the term ''nitrile'' in industrial literature. Nitriles are found in many useful compounds, including met ...
or a similar compound. This formulation was first found in "Stopette" deodorant spray, which Time Magazine
''Time'' (stylized in all caps) is an American news magazine based in New York City. For nearly a century, it was published weekly, but starting in March 2020 it transitioned to every other week. It was first published in New York City on Mar ...
called "the best-selling deodorant of the early 1950s". "Stopette" gained its prominence as the first and long-time sponsor of the game show ''What's My Line?
''What's My Line?'' is a panel game show that originally ran in the United States on the CBS Television Network from 1950 to 1967, originally in black and white and later in color, with subsequent U.S. revivals. The game uses celebrity panelis ...
'', and was later eclipsed by many other brands as the 1941 patent expired.
Between 1942 and 1957, the market for deodorants increased 600 times to become a $70 million market. Deodorants were originally marketed primarily to women, but by 1957 the market had expanded to male users, and estimates were that 50% of men were using deodorants by that date. The Ban Roll-On product led the market in sales.
In the early 1960s, the first aerosol
An aerosol is a suspension (chemistry), suspension of fine solid particles or liquid Drop (liquid), droplets in air or another gas. Aerosols can be natural or Human impact on the environment, anthropogenic. Examples of natural aerosols are fog o ...
antiperspirant in the marketplace was Gillette
Gillette is an American brand of safety razors and other personal care products including shaving supplies, owned by the multi-national corporation Procter & Gamble (P&G).
Based in Boston, Massachusetts, United States, it was owned by The Gil ...
's Right Guard
Right Guard is an American brand of deodorant and shower gel that is manufactured and sold by Thriving Brands LLC. It is the second largest brand in the male deodorant category in the United States. Right Guard was introduced in 1960 by The Gi ...
, whose brand was later sold to Henkel in 2006. Aerosols were popular because they let the user dispense a spray without coming in contact with the underarm area. By the late 1960s, half of all the antiperspirants sold in the U.S. were aerosols, and continued to grow in all sales to 82% by the early 1970s. However, the late 1970s saw two developments which greatly reduced the popularity of these products. First, in 1977 the U.S. Food and Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food ...
banned the active ingredient used in aerosols, aluminium zirconium chemicals, due to safety concerns over long term inhalation. Second, the U.S. Environmental Protection Agency
The Environmental Protection Agency (EPA) is an Independent agencies of the United States government, independent executive agency of the United States federal government tasked with environmental protection matters. President Richard Nixon pro ...
limited the use of chlorofluorocarbon
Chlorofluorocarbons (CFCs) and hydrochlorofluorocarbons (HCFCs) are fully or partly halogenated hydrocarbons that contain carbon (C), hydrogen (H), chlorine (Cl), and fluorine (F), produced as volatile derivatives of methane, ethane, and prop ...
(CFC) propellants used in aerosols due to awareness that these gases can contribute to depleting the ozone layer. As the popularity of aerosols slowly decreased, stick antiperspirants became more popular.
Classification
Deodorant
In the United States, deodorants are classified and regulated as cosmetics
Cosmetics are constituted mixtures of chemical compounds derived from either natural sources, or synthetically created ones. Cosmetics have various purposes. Those designed for personal care and skin care can be used to cleanse or protect ...
by the U.S. Food and Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food ...
(FDA)[Cosmetics Q&A: "Personal Care Products"](_blank)
U.S. Food and Drug Administration. and are designed to eliminate odor. Deodorants are often alcohol based. Alcohol initially stimulates sweating but may also temporarily kill bacteria. Other active ingredients in deodorants include sodium stearate
Sodium stearate is the sodium salt of stearic acid. This white solid is the most common soap. It is found in many types of solid deodorants, rubbers, latex paints, and inks. It is also a component of some food additives and food flavorings.Klaus ...
, sodium chloride
Sodium chloride , commonly known as salt (although sea salt also contains other chemical salts), is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. With molar masses of 22.99 and 35.45 g ...
, and stearyl alcohol. Deodorants can be formulated with other, more persistent antimicrobial
An antimicrobial is an agent that kills microorganisms or stops their growth. Antimicrobial medicines can be grouped according to the microorganisms they act primarily against. For example, antibiotics are used against bacteria, and antifungals ar ...
s such as triclosan
Triclosan (sometimes abbreviated as TCS) is an antibacterial and antifungal agent present in some consumer products, including toothpaste, soaps, detergents, toys, and surgical cleaning treatments. It is similar in its uses and mechanism of ac ...
that slow bacterial growth or with metal chelant
Chelation is a type of bonding of ions and molecules to metal ions. It involves the formation or presence of two or more separate coordinate bonds between a polydentate (multiple bonded) ligand and a single central metal atom. These ligands are ...
compounds such as EDTA
Ethylenediaminetetraacetic acid (EDTA) is an aminopolycarboxylic acid with the formula H2N(CH2CO2H)2sub>2. This white, water-soluble solid is widely used to bind to iron (Fe2+/Fe3+) and calcium ions (Ca2+), forming water-soluble complexes eve ...
. Deodorants may contain perfume
Perfume (, ; french: parfum) is a mixture of fragrant essential oils or aroma compounds (fragrances), fixatives and solvents, usually in liquid form, used to give the human body, animals, food, objects, and living-spaces an agreeable scent. Th ...
fragrances or natural essential oil
An essential oil is a concentrated hydrophobic liquid containing volatile (easily evaporated at normal temperatures) chemical compounds from plants. Essential oils are also known as volatile oils, ethereal oils, aetheroleum, or simply as the o ...
s intended to mask the odor of perspiration. In the past, deodorants included chemicals such as zinc oxide
Zinc oxide is an inorganic compound with the formula . It is a white powder that is insoluble in water. ZnO is used as an additive in numerous materials and products including cosmetics, food supplements, rubbers, plastics, ceramics, glass, cemen ...
, acids, ammonium chloride, sodium bicarbonate, and formaldehyde
Formaldehyde ( , ) (systematic name methanal) is a naturally occurring organic compound with the formula and structure . The pure compound is a pungent, colourless gas that polymerises spontaneously into paraformaldehyde (refer to section F ...
, but some of these ingredients were messy, irritating to the skin, or even carcinogenic
A carcinogen is any substance, radionuclide, or radiation that promotes carcinogenesis (the formation of cancer). This may be due to the ability to damage the genome or to the disruption of cellular metabolic processes. Several radioactive subs ...
.
Over-the-counter products, often labeled as "natural deodorant crystal", contain the chemical rock crystal
Quartz is a hard, crystalline mineral composed of silica (silicon dioxide). The atoms are linked in a continuous framework of SiO4 silicon-oxygen tetrahedra, with each oxygen being shared between two tetrahedra, giving an overall chemical form ...
s potassium alum
Potassium alum, potash alum, or potassium aluminium sulfate is a chemical compound: the double sulfate of potassium and aluminium, with chemical formula KAl(SO4)2. It is commonly encountered as the dodecahydrate, KAl(SO4)2·12H2O. It crystalli ...
or ammonium alum
Ammonium aluminium sulfate, also known as ammonium alum or just alum (though there are many different substances also called " alum"), is a white crystalline double sulfate usually encountered as the dodecahydrate, formula (NH4)Al(SO4)2·12H2O. I ...
, which prevents bacterial action on sweat. These have gained popularity as an alternative health product, in spite of concerns about possible risks related to aluminum (see below – all alum salts contain aluminum in the form of aluminum sulphate salts
In chemistry, a salt is a chemical compound consisting of an ionic assembly of positively charged cations and negatively charged anions, which results in a compound with no net electric charge. A common example is table salt, with positively c ...
) and contact dermatitis.
Vaginal deodorant, in the form of sprays, suppositories, and wipes, is often used by women to mask vaginal secretions
Vaginal lubrication is a naturally produced fluid that lubricates a
vagina. Vaginal lubrication is always present, but production increases significantly near ovulation and during sexual arousal in anticipation of sexual intercourse. Vaginal ...
. Vaginal deodorants can sometimes cause dermatitis
Dermatitis is inflammation of the skin, typically characterized by itchiness, redness and a rash. In cases of short duration, there may be small blisters, while in long-term cases the skin may become thickened. The area of skin involved can v ...
.
Deodorant antiperspirant
In the United States, deodorants combined with antiperspirant agents are classified as drugs
A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via inhalat ...
by the FDA. Antiperspirants attempt to stop or significantly reduce perspiration and thus reduce the moist climate in which bacteria thrive. Aluminium chloride
Aluminium chloride, also known as aluminium trichloride, is an inorganic compound with the formula . It forms hexahydrate with the formula , containing six water molecules of hydration. Both are colourless crystals, but samples are often contam ...
, aluminium chlorohydrate
Aluminium chlorohydrate is a group of water-soluble, specific aluminium salts having the general formula Aln Cl(3n-m)( OH)m. It is used in cosmetics as an antiperspirant and as a coagulant in water purification.
In water purification, this compou ...
, and aluminium
Aluminium (aluminum in American and Canadian English) is a chemical element with the symbol Al and atomic number 13. Aluminium has a density lower than those of other common metals, at approximately one third that of steel. I ...
-zirconium
Zirconium is a chemical element with the symbol Zr and atomic number 40. The name ''zirconium'' is taken from the name of the mineral zircon, the most important source of zirconium. The word is related to Persian '' zargun'' (zircon; ''zar-gun'', ...
compounds, most notably aluminium zirconium tetrachlorohydrex gly and aluminium zirconium trichlorohydrex gly, are frequently used in antiperspirants. Aluminium chlorohydrate and aluminium-zirconium tetrachlorohydrate gly are the most frequent active ingredients in commercial antiperspirants. Aluminium-based complexes react with the electrolyte
An electrolyte is a medium containing ions that is electrically conducting through the movement of those ions, but not conducting electrons. This includes most soluble salts, acids, and bases dissolved in a polar solvent, such as water. Upon dis ...
s in the sweat to form a gel plug in the duct of the sweat gland. The plugs prevent the gland from excreting liquid and are removed over time by the natural sloughing
In biology, moulting (British English), or molting (American English), also known as sloughing, shedding, or in many invertebrates, ecdysis, is the manner in which an animal routinely casts off a part of its body (often, but not always, an outer ...
of the skin. The metal salts work in another way to prevent sweat from reaching the surface of the skin: the aluminium salts interact with the keratin fibrils in the sweat ducts and form a physical plug that prevents sweat from reaching the skin's surface. Aluminium salts also have a slight astringent
An astringent (sometimes called adstringent) is a chemical that shrinks or constricts body tissues. The word derives from the Latin ''adstringere'', which means "to bind fast". Calamine lotion, witch hazel, and yerba mansa, a Californian plant ...
effect on the pores; causing them to contract, further preventing sweat from reaching the surface of the skin. The blockage of a large number of sweat glands reduces the amount of sweat produced in the underarms, though this may vary from person to person. Methenamine in the form of cream or spray is effective in the treatment of excessive sweating and attendant odor. Antiperspirants are usually best applied before bed.
Product formulations and formats
Formulations
Common and historical formulations for deodorants include the following active ingredients:
:* Aluminum
Aluminium (aluminum in American and Canadian English) is a chemical element with the symbol Al and atomic number 13. Aluminium has a density lower than those of other common metals, at approximately one third that of steel. It has ...
salts
In chemistry, a salt is a chemical compound consisting of an ionic assembly of positively charged cations and negatively charged anions, which results in a compound with no net electric charge. A common example is table salt, with positively c ...
( aluminum chlorohydrate, aluminum zirconium tetrachlorohydrex gly, and others) – used as the basis for almost all non-prescription (everyday) antiperspirants. The aluminum reacts within the sweat gland to form a colloid
A colloid is a mixture in which one substance consisting of microscopically dispersed insoluble particles is suspended throughout another substance. Some definitions specify that the particles must be dispersed in a liquid, while others extend ...
which physically prevents sweating.
:* Alum
An alum () is a type of chemical compound, usually a hydrated double salt, double sulfate salt (chemistry), salt of aluminium with the general chemical formula, formula , where is a valence (chemistry), monovalent cation such as potassium or a ...
(typically potassium alum
Potassium alum, potash alum, or potassium aluminium sulfate is a chemical compound: the double sulfate of potassium and aluminium, with chemical formula KAl(SO4)2. It is commonly encountered as the dodecahydrate, KAl(SO4)2·12H2O. It crystalli ...
or ammonium alum
Ammonium aluminium sulfate, also known as ammonium alum or just alum (though there are many different substances also called " alum"), is a white crystalline double sulfate usually encountered as the dodecahydrate, formula (NH4)Al(SO4)2·12H2O. I ...
, also described as "rock alum", or "rock crystal", or "natural deodorant"). Alum is a natural crystalline product widely used both historically and in modern times as a deodorant, because it inhibits bacterial action. The word 'alum' is a historical term for aluminum sulfate
Aluminium sulfate is a salt with the formula Al2 (SO4)3. It is soluble in water and is mainly used as a coagulating agent (promoting particle collision by neutralizing charge) in the purification of drinking water and wastewater treatment plan ...
salts
In chemistry, a salt is a chemical compound consisting of an ionic assembly of positively charged cations and negatively charged anions, which results in a compound with no net electric charge. A common example is table salt, with positively c ...
, therefore all alum products will contain aluminum, albeit in a different chemical form from antiperspirants.
:* Bactericidal
A bactericide or bacteriocide, sometimes abbreviated Bcidal, is a substance which kills bacteria. Bactericides are disinfectants, antiseptics, or antibiotics.
However, material surfaces can also have bactericidal properties based solely on their ...
products such as triclosan
Triclosan (sometimes abbreviated as TCS) is an antibacterial and antifungal agent present in some consumer products, including toothpaste, soaps, detergents, toys, and surgical cleaning treatments. It is similar in its uses and mechanism of ac ...
(TCS) and parabens
Parabens are a class of widely used preservatives in cosmetic and pharmaceutical products. Chemically, they are a series of parahydroxybenzoates or esters of parahydroxybenzoic acid (also known as 4-hydroxybenzoic acid). Parabens are effective ...
kill bacteria on the skin.
:* Alcohols and related compounds such as propylene glycol
Propylene glycol (IUPAC name: propane-1,2-diol) is a viscous, colorless liquid, which is nearly odorless but possesses a faintly sweet taste. Its chemical formula is CH3CH(OH)CH2OH.
Containing two alcohol groups, it is classed as a diol. It i ...
– these products can have both drying and bactericidal
A bactericide or bacteriocide, sometimes abbreviated Bcidal, is a substance which kills bacteria. Bactericides are disinfectants, antiseptics, or antibiotics.
However, material surfaces can also have bactericidal properties based solely on their ...
effects.
:* Methenamine (hexamethylenetetramine, also known as hexamine or urotropin) is a powerful antiperspirant, often used for severe sweat-related issues, as well as prevention of sweating within the sockets of prosthetic
In medicine, a prosthesis (plural: prostheses; from grc, πρόσθεσις, prósthesis, addition, application, attachment), or a prosthetic implant, is an artificial device that replaces a missing body part, which may be lost through trau ...
devices used by amputees
Amputation is the removal of a limb by trauma, medical illness, or surgery. As a surgical measure, it is used to control pain or a disease process in the affected limb, such as malignancy or gangrene. In some cases, it is carried out on indivi ...
.
:* Acidifier
Acidifiers are inorganic chemicals that, put into a human (or other mammalian) body, either produce or become acid.
These chemicals increase the level of gastric acid in the stomach
The stomach is a muscular, hollow organ in the gastroin ...
s and pH neutral products – deodorants that prevent bacterial action by enhancing (or at least, not depleting) the skin's natural slight acidity, known as the acid mantle The acid mantle is a very fine, slightly acidic film on the surface of human skin acting as a barrier to bacteria, viruses and other potential contaminants that might penetrate the skin. Sebum is secreted by the sebaceous gland and when mixed wit ...
, which naturally reduces bacterial action but can be compromised by typically alkaline soaps and skin products.
:* Masking scents – other strong or overriding scents of a pleasing type may be used, used to mask bodily odors. Typically these are strongly smelling plant extracts or synthetic aromas.
:* Activated charcoal and other products capable of absorbing sweat and/or smell. Although charcoal most often has a black color, the activated charcoal used in deodorants may be a very light color for aesthetic reasons.
:* Less commonly used, products such as milk of magnesia
Magnesium hydroxide is the inorganic compound with the chemical formula Mg(OH)2. It occurs in nature as the mineral brucite. It is a white solid with low solubility in water (). Magnesium hydroxide is a common component of antacids, such as milk ...
(a thick liquid suspension
Suspension or suspended may refer to:
Science and engineering
* Suspension (topology), in mathematics
* Suspension (dynamical systems), in mathematics
* Suspension of a ring, in mathematics
* Suspension (chemistry), small solid particles suspend ...
of magnesium hydroxide
Magnesium hydroxide is the inorganic compound with the chemical formula Mg(OH)2. It occurs in nature as the mineral brucite. It is a white solid with low solubility in water (). Magnesium hydroxide is a common component of antacids, such as milk ...
) are sometimes used as deodorants. Many milk of magnesia products contain small amounts of sodium hypochlorite
Sodium hypochlorite (commonly known in a dilute solution as bleach) is an Inorganic chemistry, inorganic chemical compound with the chemical formula, formula NaOCl (or NaClO), comprising a sodium cation () and a hypochlorite anion (or ). It may ...
(bleach
Bleach is the generic name for any chemical product that is used industrially or domestically to remove color (whitening) from a fabric or fiber or to clean or to remove stains in a process called bleaching. It often refers specifically, to ...
) at very low levels that are safe for ingestion and skin application. Sodium hypochlorite is a powerful bactericide
A bactericide or bacteriocide, sometimes abbreviated Bcidal, is a substance which kills bacteria. Bactericides are disinfectants, antiseptics, or antibiotics.
However, material surfaces can also have bactericidal properties based solely on thei ...
, and it is possible that its presence in a product that can dry onto the skin, may explain this use as a deodorant. (''Safety info: bleach is caustic
Caustic most commonly refers to:
* Causticity, a property of various corrosive substances
** Sodium hydroxide, sometimes called ''caustic soda''
** Potassium hydroxide, sometimes called ''caustic potash''
** Calcium oxide, sometimes called ''caus ...
and extremely poisonous, and can be lethal, in higher concentrations.'')
Formats
Deodorants and antiperspirants come in many forms. What is commonly used varies in different countries. In Europe, aerosol spray
Aerosol spray is a type of dispensing system which creates an aerosol mist of liquid particles. It comprises a can or bottle that contains a payload, and a propellant under pressure. When the container's valve is opened, the payload is forced out ...
s are popular, as are cream and roll-on forms. In North America, solid or gel forms are dominant.
Health effects
After using a deodorant containing zirconium, the skin may develop an allergic
Allergies, also known as allergic diseases, refer a number of conditions caused by the hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic der ...
, axillary granuloma response. Antiperspirants with propylene glycol
Propylene glycol (IUPAC name: propane-1,2-diol) is a viscous, colorless liquid, which is nearly odorless but possesses a faintly sweet taste. Its chemical formula is CH3CH(OH)CH2OH.
Containing two alcohol groups, it is classed as a diol. It i ...
, when applied to the axilla
The axilla (also, armpit, underarm or oxter) is the area on the human body directly under the shoulder joint. It includes the axillary space, an anatomical space within the shoulder girdle between the arm and the thoracic cage, bounded superior ...
e, can cause irritation and may promote sensitization to other ingredients in the antiperspirant. Deodorant crystals containing synthetically made potassium alum
Potassium alum, potash alum, or potassium aluminium sulfate is a chemical compound: the double sulfate of potassium and aluminium, with chemical formula KAl(SO4)2. It is commonly encountered as the dodecahydrate, KAl(SO4)2·12H2O. It crystalli ...
were found to be a weak irritant to the skin. Unscented deodorant is available for those with sensitive skin. Frequent use of deodorants was associated with blood concentrations of the synthetic musk
Synthetic musks are a class of synthetic aroma compounds to emulate the scent of deer musk and other animal musks (castoreum and civet). Synthetic musks have a clean, smooth and sweet scent lacking the fecal notes of animal musks. They are used as ...
galaxolide
Galaxolide (trade name; also known as Abbalide, Pearlide, Astrolide, Musk 50, Polarlide; chemical name 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8,-hexamethyl-cyclopenta 'g''enzopyran or HHCB, hexamethylindanopyran) is a synthetic musk with a clean sweet ...
.
Aluminum
Many deodorants and antiperspirants contain aluminium
Aluminium (aluminum in American and Canadian English) is a chemical element with the symbol Al and atomic number 13. Aluminium has a density lower than those of other common metals, at approximately one third that of steel. I ...
in the form of aluminium salts such as aluminium chlorohydrate
Aluminium chlorohydrate is a group of water-soluble, specific aluminium salts having the general formula Aln Cl(3n-m)( OH)m. It is used in cosmetics as an antiperspirant and as a coagulant in water purification.
In water purification, this compou ...
.
The US Food and Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food ...
, in a 2003 paper discussing deodorant safety, concluded that "despite many investigators looking at this issue, the agency does not find data from topical and inhalation chronic exposure animal and human studies submitted to date sufficient to change the monograph status of aluminum containing antiperspirants", therefore allowing their use and stating they will keep monitoring the scientific literature. Members of the Scientific Committee on Consumer Safety
The Scientific Committee on Consumer Safety (SCCS) is one of the independent scientific committees managed by the Directorate-General for Health and Consumer Protection of the European Commission, which provide scientific advice to the commission ...
(SCCS) of the European Commission
The European Commission (EC) is the executive of the European Union (EU). It operates as a cabinet government, with 27 members of the Commission (informally known as "Commissioners") headed by a President. It includes an administrative body o ...
concluded similarly in 2015, that "due to the lack of adequate data on dermal penetration to estimate the internal dose of aluminium following cosmetic uses, risk assessment cannot be performed." In the light of new data in 2020 the SCCS considered aluminium compounds safe up to 6.25% in non-spray deodorants or non-spray antiperspirants and 10.60% in spray deodorants or spray antiperspirants.
Myths and claims related to aluminium compounds in deodorants
Common myths and marketing claims for aluminium in deodorants (including aluminum in alum products) include claims:
* That aluminium in deodorants applied to the skin is a risk factor for some cancers (notably breast cancer) and some forms of dementia
Dementia is a disorder which manifests as a set of related symptoms, which usually surfaces when the brain is damaged by injury or disease. The symptoms involve progressive impairments in memory, thinking, and behavior, which negatively affe ...
.
* That aluminium in antiperspirants can enter the body (possibly through shaving cuts).
* That aluminium in alum "natural deodorant" products is "safer" because it is "too large" to enter the body.
Of note, the parts of the body which are commonly shaved and also commonly treated with deodorants, such as the armpit
The axilla (also, armpit, underarm or oxter) is the area on the human body directly under the shoulder joint. It includes the axillary space, an anatomical space within the shoulder girdle between the arm and the thoracic cage, bounded superior ...
s, contain substantial deposits of subcutaneous fat
The subcutaneous tissue (), also called the hypodermis, hypoderm (), subcutis, superficial fascia, is the lowermost layer of the integumentary system in vertebrates. The types of cells found in the layer are fibroblasts, adipose cells, and mac ...
. Shaving cuts would be extremely unlikely to penetrate sufficiently beyond the very outer layers of the skin, for much if any product to enter the bloodstream.
Alzheimer's disease
A 2014 review of 469 peer-reviewed studies examining the effect of exposure to aluminum products concluded "that health risks posed by exposure to inorganic depend on its physical and chemical forms and that the response varies with route of administration, magnitude, duration and frequency of exposure. These results support previous conclusions that there is little evidence that exposure to metallic Al, the Al oxides or its salts increases risk for Alzheimer's disease
Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term me ...
, genetic damage or cancer".
Breast cancer
The claim that breast cancer is believed to be linked with deodorant use has been widely circulated and appears to originate from a spam
Spam may refer to:
* Spam (food), a canned pork meat product
* Spamming, unsolicited or undesired electronic messages
** Email spam, unsolicited, undesired, or illegal email messages
** Messaging spam, spam targeting users of instant messaging ( ...
email sent in 1999; however, there is no evidence to support the existence of such a link. The myth circulates in two forms:
* ''Antiperspirants block the "purging" of toxins which build up in the body and cause breast cancer:'' There is no truth to this claim. Sweat glands simply do not have this function, and this myth is not scientifically plausible. Perspiration from the eccrine sweat glands comprises 99% water, with some salt
Salt is a mineral composed primarily of sodium chloride (NaCl), a chemical compound belonging to the larger class of salts; salt in the form of a natural crystalline mineral is known as rock salt or halite. Salt is present in vast quantitie ...
(sodium chloride) and only trace amounts of lactic acid
Lactic acid is an organic acid. It has a molecular formula . It is white in the solid state and it is miscible with water. When in the dissolved state, it forms a colorless solution. Production includes both artificial synthesis as well as natu ...
(almost entirely processed in the liver
The liver is a major Organ (anatomy), organ only found in vertebrates which performs many essential biological functions such as detoxification of the organism, and the Protein biosynthesis, synthesis of proteins and biochemicals necessary for ...
), urea
Urea, also known as carbamide, is an organic compound with chemical formula . This amide has two amino groups (–) joined by a carbonyl functional group (–C(=O)–). It is thus the simplest amide of carbamic acid.
Urea serves an important r ...
(almost entirely excreted by the kidney
The kidneys are two reddish-brown bean-shaped organs found in vertebrates. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal arteries; blood ...
s), and only very small amounts of all other components. Perspiration from the apocrine sweat glands (those in the armpits and groin, which are more responsible for body odor) also include waste protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
s, carbohydrate
In organic chemistry, a carbohydrate () is a biomolecule consisting of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with a hydrogen–oxygen atom ratio of 2:1 (as in water) and thus with the empirical formula (where ''m'' may or ma ...
s, and fatty acid
In chemistry, particularly in biochemistry, a fatty acid is a carboxylic acid with an aliphatic chain, which is either saturated or unsaturated. Most naturally occurring fatty acids have an unbranched chain of an even number of carbon atoms, fr ...
s which would otherwise be processed by other organs such as the liver.
It is possible that there has been confusion between sweat glands, and the lymph nodes
A lymph node, or lymph gland, is a kidney-shaped organ of the lymphatic system and the adaptive immune system. A large number of lymph nodes are linked throughout the body by the lymphatic vessels. They are major sites of lymphocytes that inclu ...
deep within the armpits which form part of the immune system
The immune system is a network of biological processes that protects an organism from diseases. It detects and responds to a wide variety of pathogens, from viruses to parasitic worms, as well as cancer cells and objects such as wood splinte ...
and help filter toxins, but if so, there is no evidence at all of such "blocking" of lymph nodes, nor any scientifically plausible route by which this could result from deodorant use.
* ''Aluminum in antiperspirants can enter the body (possibly through cuts) and cause breast cancer:'' There is no current evidence to support this claim, nor any convincing evidence that it is true. A fact often cited to back up this claim is that more breast cancers occur in the part of the breast near the armpits, however breast tissue
The breast is one of two prominences located on the upper ventral region of a primate's torso. Both females and males develop breasts from the same embryological tissues.
In females, it serves as the mammary gland, which produces and secret ...
is not evenly spread out, and the part of the breast near the armpit (the Tail of Spence
The tail of Spence (Spence's tail, axillary process, axillary tail) has historically been described as an extension of the tissue of the upper outer quadrant of the breast traveling into the axilla. The "axillary tail" has been reported to pass in ...
) simply contains much more breast tissue than the other quadrants, making it much more likely that any cancer would occur in that location. See above for current scientific knowledge regarding aluminum in deodorants.
The National Cancer Institute
The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. ...
states that "no scientific evidence links the use of these products to the development of breast cancer" and that "no clear evidence that the use of aluminum-containing underarm antiperspirants or cosmetics increases the risk of breast cancer", but also concludes that studies of antiperspirants and deodorants and breast cancer have provided conflicting results, additional research would be needed to determine whether a relationship exists".
Another constituent of deodorant products that has given cause for concern are paraben
Parabens are a class of widely used preservatives in cosmetic and pharmaceutical products. Chemically, they are a series of parahydroxybenzoates or esters of parahydroxybenzoic acid (also known as 4-hydroxybenzoic acid). Parabens are effective p ...
s, a chemical additive.[ According to the ]American Cancer Society
The American Cancer Society (ACS) is a nationwide voluntary health organization dedicated to eliminating cancer. Established in 1913, the society is organized into six geographical regions of both medical and lay volunteers operating in more than ...
, "studies have not shown any direct link between parabens and any health problems, including breast cancer".
Kidney dysfunction
The FDA has "acknowledge that small amounts of aluminium can be absorbed from the gastrointestinal tract and through the skin", leading to a warning "that people with kidney disease
Kidney disease, or renal disease, technically referred to as nephropathy, is damage to or disease of a kidney. Nephritis is an inflammatory kidney disease and has several types according to the location of the inflammation. Inflammation can ...
may not be aware that the daily use of antiperspirant drug products containing aluminium may put them at a higher risk because of exposure to aluminium in the product."[ - updated links]
PubMed link
Government website
direct federal register entry
The agency warns people with kidney dysfunction to consult a doctor
Doctor or The Doctor may refer to:
Personal titles
* Doctor (title), the holder of an accredited academic degree
* A medical practitioner, including:
** Physician
** Surgeon
** Dentist
** Veterinary physician
** Optometrist
*Other roles
** ...
before using antiperspirants containing aluminum.
Aerosol burns and frostbite
If aerosol deodorant is held close to the skin for long enough, it can cause an aerosol burn
An aerosol frostbite of the skin is an injury to the body caused by the pressurized gas within an aerosol spray cooling quickly, with the sudden drop in temperature sufficient to cause frostbite to the applied area. Medical studies have noted an i ...
—a form of frostbite
Frostbite is a skin injury that occurs when exposed to extreme low temperatures, causing the freezing of the skin or other tissues, commonly affecting the fingers, toes, nose, ears, cheeks and chin areas. Most often, frostbite occurs in the ha ...
. In controlled tests, spray deodorants have been shown to cause temperature drops of over 60 °C in a short period of time.
Clothing
Aluminium zirconium tetrachlorohydrex gly, a common antiperspirant, can react with sweat to create yellow stains on clothing. Underarm liners Underarm liners are an alternative to antiperspirants. The liners are applied directly to clothing. They contain absorbent material that wicks away moisture from sweat, keeping the axilla dry. Underarm liners were used more commonly before chemical ...
are an antiperspirant alternative that does not leave stains.
See also
* Air freshener
* Aluminum chlorohydrate
* Perfume
Perfume (, ; french: parfum) is a mixture of fragrant essential oils or aroma compounds (fragrances), fixatives and solvents, usually in liquid form, used to give the human body, animals, food, objects, and living-spaces an agreeable scent. Th ...
References
External links
Antiperspirants/Deodorants and breast cancer
{{Authority control
Personal hygiene products
Aerosols
American inventions
Body odor