Denervation supersensitivity/Denervation hypersensitivity is the sharp increase of sensitivity of

postsynaptic membrane Chemical synapses are biological junctions through which neurons' signals can be sent to each other and to non-neuronal cells such as those in muscles or glands. Chemical synapses allow neurons to form circuits within the central nervous syste ...

s to a chemical transmitter after

denervation Denervation is any loss of nerve supply regardless of the cause. If the nerves lost to denervation are part of the neuronal communication to a specific function in the body then altered or a loss of physiological functioning can occur. Denervation ...

.S. Z. Langer, "Denervation Supersensitivity", in: ''Principles of Receptor Research'' Volume 2 of the series Handbook of Psychopharmacology pp 245-280 It is a compensatory change.

References

{{reflist Peripheral nervous system