Demetrius II or Demetrios II may refer to:
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Demetrius II Aetolicus (died 229 BC), king of Macedon
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Demetrius II of India
Demetrius II (Greek: ) was an Indo-Greek king who ruled briefly during the 2nd century BC. Little is known about him and there are different views about how to date him. Earlier authors such as Tarn and Narain saw him as a son and sub-king of Dem ...
(died ca. 150 BC)
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Demetrius II Nicator (died 125 BC), ruler of the Seleucid Empire
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Demetrius II of Abkhazia (ruled 837/38–872/73 AD)
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Demetrius II of Georgia (died 1289 AD)
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Demetrius I of Georgia (died 1156 AD)
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Pope Demetrius II of Alexandria, ruled in 1861–1870
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MV ''Demetrios II'', a cargo ship wrecked in 1998
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