In general usage, ''de novo'' (literally 'of new') is a Latin expression used in English to mean 'from the beginning', 'anew'.
De novo may also refer to:
Science and computers
*
''De novo'' mutation, a new germline mutation not inherited from either parent
* ''De novo''
protein design
Protein design is the rational design of new protein molecules to design novel activity, behavior, or purpose, and to advance basic understanding of protein function. Proteins can be designed from scratch (''de novo'' design) or by making calcula ...
, the creation of a protein sequence that is not based on existing, natural sequences
*
''De novo'' protein structure prediction, the prediction of a protein's 3D structure, based only on its sequence
*
''De novo'' synthesis of complex molecules from simple molecules in chemistry
*
''De novo'' transcriptome assembly, the method of creating a transcriptome without a reference genome, using
de novo sequence assembly
*
''De novo'' gene birth, the emergence of genes from non-coding sequence
* ''De novo'' assembly in
genomics
Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dim ...
* ''De Novo'' classification, a pathway to classify new medical devices provided by the US
Federal Food, Drug, and Cosmetic Act
The United States Federal Food, Drug, and Cosmetic Act (abbreviated as FFDCA, FDCA, or FD&C) is a set of laws passed by the United States Congress in 1938 giving authority to the U.S. Food and Drug Administration (FDA) to oversee the safety of f ...
* Denovo, a supercomputer project that simulates nuclear reactions; see
Other
*
''De novo'' review, an appellate standard of review for legal issues
*
Trial ''de novo'', or a new trial in the legal system
* ''De novo'' bank, a
state bank
A state bank is generally a financial institution that is chartered by a federated state, as opposed to one regulated at the federal or national level. State banks differ from a reserve bank in that it does not necessarily control monetary policy ...
that has been in operation for five years or less
* De Novo, a
public housing estate in Kai Tak, Hong Kong
*
Denovo (band)
Denovo is an Italian New wave music, New wave group formed in the early 1980s in Catania. They are also referred to as I Denovo.
Background
The band officially debuted with the EP ''Niente insetti su Wilma'', released in 1984, which had some lo ...
, a 1980s Italian new wave group
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Latin words and phrases