David Webb (pharmacologist)
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David John Webb, (born 1 September 1953) is a British physician, scientist and
clinical pharmacologist Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemic ...
, who currently holds the Christison Chair of Therapeutics and Clinical Pharmacology at the University of Edinburgh. He was appointed to the Christison Chair of Therapeutics and Clinical Pharmacology at the University of Edinburgh in 1995, and from 1998 to 2001 he was Head of the University's Department of Medical Sciences there. He established its Centre for Cardiovascular Science in 2000.


Early life and education

David Webb was born on 1 September 1953 to Alfred And Edna Webb, and was educated at Dulwich College before studying medicine at the
London Hospital Medical School , mottoeng = Temper the bitter things in life with a smile , parent = Queen Mary University of London , president = Lord Mayor of London , head_label = Warden , head = Mark Caulfield , students = 3,410 , undergrad = 2,2 ...
. Following junior appointments, Webb worked at the Medical Research Council Blood Pressure Unit in Glasgow and trained as a cardiovascular physician and clinical pharmacologist at St George's Hospital and Medical School.


Career and research

Webb moved to a senior lectureship in medicine at the University of Edinburgh in 1990, where he directed its newly established Clinical Research Centre. He was appointed to the Christison Chair of Therapeutics and Clinical Pharmacology at the University of Edinburgh in 1995. He headed the Department of Medical Sciences and led a Wellcome Trust Cardiovascular Initiative from 1998 to 2001, then created and led the University's Centre for Cardiovascular Science from 2000 to 2004. Webb has acted on behalf on several professional organisations: He served as clinical vice-president of the British Pharmacological Society from 1996 to 1998 and later as its president from 2016 to 2018; chair of the Royal College of Physicians' Committee on Clinical Pharmacology during 1998 and 1989; and chaired the British Pharmacological Society's committee of heads and professors of clinical pharmacology from 2004 to 2007. He became the vice-president of the
Royal College of Physicians of Edinburgh The Royal College of Physicians of Edinburgh (RCPE) is a medical royal college in Scotland. It is one of three organisations that sets the specialty training standards for physicians in the United Kingdom. It was established by Royal charter ...
in 2006 and served until 2009.


Advocation for clinical pharmacology and prescribing safety

In 2006, Webb advocated with colleagues against the decline of clinical pharmacology as a speciality within the United Kingdom, noting that the number of clinical pharmacologists had dropped by 24% from 1993 to 2003, whereas the number of practitioners in all other medical specialties had increased by 79%. He also participated in raising awareness about poor medical undergraduate prescribing skills and in 2009 he provided evidence to the United Kingdom select committee on patient safety regarding prescription errors, of which an excerpt is shown below: This ultimately led to the creation and introduction by the British Pharmacological Society and UK
Medical Schools Council The Medical Schools Council is an organisation that represents 41 medical schools and one post graduate school in the United Kingdom. The membership is made up of the heads, or deans of the medical schools. It was formerly known as the Council o ...
of th
Prescribing Safety Assessment
which is now taken by all undergraduate medical students in the United Kingdom.


Cardiovascular research

Webb's scientific research focuses on novel treatments for
hypertension Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. High blood pressure usually does not cause symptoms. Long-term high bl ...
and
cardiovascular risk Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs include stroke, ...
, particularly with regards to blood vessel structure and function. His publications include first-in-human studies with renin inhibitors and endothelin
antagonists An antagonist is a character in a story who is presented as the chief foe of the protagonist. Etymology The English word antagonist comes from the Greek ἀνταγωνιστής – ''antagonistēs'', "opponent, competitor, villain, enemy, riv ...
, including exploration of the role of endothelin antagonists as treatment for vascular and
renal disease Kidney disease, or renal disease, technically referred to as nephropathy, is damage to or disease of a kidney. Nephritis is an inflammatory kidney disease and has several types according to the location of the inflammation. Inflammation can b ...
. He has also contributed to the current understanding of arterial stiffness and its role in cardiovascular risk.


Awards

Webb was elected a Fellow of the Royal College of Physicians in 1992, a Fellow of the Academy of Medical Sciences in 1999, and a Fellow of the Royal Society of Edinburgh in 2004. He is an honorary fellow of the British Pharmacological Society and of the Faculty of Pharmaceutical Physicians. He was appointed Commander of the Order of the British Empire (CBE) in the
2020 Birthday Honours The Queen's Birthday Honours for 2020 are appointments by some of the 16 Commonwealth realms of Queen Elizabeth II to various orders and honours to reward and highlight good works by citizens of those countries. The Birthday Honours are awarded ...
for services to clinical pharmacology, research and education.


References


External links

* * {{DEFAULTSORT:Webb, David 1953 births Place of birth missing (living people) Living people Clinical pharmacologists Fellows of the Royal College of Physicians Fellows of the Royal Society of Edinburgh Commanders of the Order of the British Empire