David Paul von Hansemann (5 September 1858 – 1920) was a German

pathologist Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in t ...

born in

Eupen Eupen (, ; ; formerly ) is the capital of German-speaking Community of Belgium and is a city and municipality in the Belgian province of Liège, from the German border ( Aachen), from the Dutch border (Maastricht) and from the " High Fens" ...

east Belgium The German-speaking Community (german: links=no, Deutschsprachige Gemeinschaft, or DG; french: links=no, Communauté germanophone; nl, links=no, Duitstalige Gemeenschap), since 2017 also known as East Belgium (german: links=no, Ostbelgien), is ...

. He is remembered for his work in the field of

oncology Oncology is a branch of medicine that deals with the study, treatment, diagnosis and prevention of cancer. A medical professional who practices oncology is an ''oncologist''. The name's etymological origin is the Greek word ὄγκος (''� ...

, in particular, his concept pertaining to

anaplasia Anaplasia (from grc, ἀνά ''ana'', "backward" + πλάσις ''plasis'', "formation") is a condition of cells with poor cellular differentiation, losing the morphological characteristics of mature cells and their orientation with respect to e ...

of cancer cells. He studied medicine at the Universities of

Berlin Berlin ( , ) is the capital and List of cities in Germany by population, largest city of Germany by both area and population. Its 3.7 million inhabitants make it the European Union's List of cities in the European Union by population within ci ...

Kiel Kiel () is the capital and most populous city in the northern German state of Schleswig-Holstein, with a population of 246,243 (2021). Kiel lies approximately north of Hamburg. Due to its geographic location in the southeast of the Jutland ...

and

Leipzig Leipzig ( , ; Upper Saxon: ) is the most populous city in the German state of Saxony. Leipzig's population of 605,407 inhabitants (1.1 million in the larger urban zone) as of 2021 places the city as Germany's eighth most populous, as ...

, and following graduation spent nine years as an assistant to

Rudolf Virchow Rudolf Ludwig Carl Virchow (; or ; 13 October 18215 September 1902) was a German physician, anthropologist, pathologist, prehistorian, biologist, writer, editor, and politician. He is known as "the father of modern pathology" and as the founder ...

(1821-1902) in

. In 1890 he became habilitated in

pathological anatomy Anatomical pathology (''Commonwealth'') or Anatomic pathology (''U.S.'') is a medical specialty that is concerned with the diagnosis of disease based on the macroscopic, microscopic, biochemical, immunologic and molecular examination o ...

, and in 1897 obtained the title of professor. In 1907 he began work as a

prosector A prosector is a person with the special task of preparing a dissection for demonstration, usually in medical schools or hospitals. Many important anatomists began their careers as prosectors working for lecturers and demonstrators in anatomy and p ...

Friedrichshain Friedrichshain () is a quarter (''Ortsteil'') of the borough of Friedrichshain-Kreuzberg in Berlin, Germany. From its creation in 1920 until 2001, it was a freestanding city borough. Formerly part of East Berlin, it is adjacent to Mitte, Prenzl ...

city hospital. During

World War I World War I (28 July 1914 11 November 1918), often abbreviated as WWI, was one of the deadliest global conflicts in history. Belligerents included much of Europe, the Russian Empire, the United States, and the Ottoman Empire, with fightin ...

he served as an army pathologist. His name is associated with "Hansemann

macrophages Macrophages (abbreviated as M φ, MΦ or MP) ( el, large eaters, from Greek ''μακρός'' (') = large, ''φαγεῖν'' (') = to eat) are a type of white blood cell of the immune system that engulfs and digests pathogens, such as cancer ce ...

" (also known as "Hansemann cells"), which are large mononuclear cells containing Michaelis-Gutmann bodies that affect the

urinary tract The urinary system, also known as the urinary tract or renal system, consists of the kidneys, ureters, bladder, and the urethra. The purpose of the urinary system is to eliminate waste from the body, regulate blood volume and blood pressure, c ...

kidney The kidneys are two reddish-brown bean-shaped organs found in vertebrates. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal arteries; blo ...

Associated works

* ''Über asymmetrische Zelltheilung in Epithelkrebsen und deren biologische Bedeutung''. Virchow's Archiv für pathologische Anatomie und Physiologie und für klinische Medicin, 1890, 779: 299–326. (''About asymmetrical cell division in epithelial cancers and their biological significance'', Anaplasia first described). * ''Die mikroskopische Diagnose der bösartigen Geschwülste''. Berlin, 1897; 2nd edition, 1902. * Books on David Paul von Hansemann: * "David Paul von Hansemann: Contributions to Oncology (Context, Comments and Translations)", by Leon P. Bignold, Brian L.D. Coghlan, Hubertus P.A. Jersmann (2007);
Birkhauser BioSciences

References

''David Paul von Hansemann''
@

Who Named It ''Whonamedit?'' is an online English-language dictionary of medical eponyms and the people associated with their identification. Though it is a dictionary, many eponyms and persons are presented in extensive articles with comprehensive bibliograp ...

German pathologists German oncologists People from Liège Province 1858 births 1920 deaths {{Germany-med-bio-stub