David Horn (Israeli Physicist)
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David Horn (Hebrew: דוד הורן; born: 10 September 1937) is a
Professor Professor (commonly abbreviated as Prof.) is an academic rank at universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a "person who professes". Professors ...
(Emeritus) of
Physics Physics is the natural science that studies matter, its fundamental constituents, its motion and behavior through space and time, and the related entities of energy and force. "Physical science is that department of knowledge which r ...
in the School of Physics and
Astronomy Astronomy () is a natural science that studies celestial objects and phenomena. It uses mathematics, physics, and chemistry in order to explain their origin and evolution. Objects of interest include planets, moons, stars, nebulae, g ...
at
Tel Aviv University Tel Aviv University (TAU) ( he, אוּנִיבֶרְסִיטַת תֵּל אָבִיב, ''Universitat Tel Aviv'') is a public research university in Tel Aviv, Israel. With over 30,000 students, it is the largest university in the country. Locate ...
(TAU),
Israel Israel (; he, יִשְׂרָאֵל, ; ar, إِسْرَائِيل, ), officially the State of Israel ( he, מְדִינַת יִשְׂרָאֵל, label=none, translit=Medīnat Yīsrāʾēl; ), is a country in Western Asia. It is situated ...
. He has served as Vice-
Rector Rector (Latin for the member of a vessel's crew who steers) may refer to: Style or title *Rector (ecclesiastical), a cleric who functions as an administrative leader in some Christian denominations *Rector (academia), a senior official in an edu ...
of TAU, Chairman of the School of Physics and Astronomy and as
Dean Dean may refer to: People * Dean (given name) * Dean (surname), a surname of Anglo-Saxon English origin * Dean (South Korean singer), a stage name for singer Kwon Hyuk * Dean Delannoit, a Belgian singer most known by the mononym Dean Titles * ...
of the Faculty of
Exact Sciences The exact sciences, sometimes called the exact mathematical sciences, are those sciences "which admit of absolute precision in their results"; especially the mathematical sciences. Examples of the exact sciences are mathematics, optics, astron ...
in TAU. He is a fellow of the American Physical Society, nominated for "contributions to theoretical particle physics, including the seminal work on finite energy sum rules, research of the phenomenology of hadronic processes, and investigation of Hamiltonian lattice theories".


Early life and education

David Horn was born and educated in
Haifa Haifa ( he, חֵיפָה ' ; ar, حَيْفَا ') is the third-largest city in Israel—after Jerusalem and Tel Aviv—with a population of in . The city of Haifa forms part of the Haifa metropolitan area, the third-most populous metropol ...
. He graduated from the Reali School in 1955. He began his academic studies in Physics at the Technion in Haifa in 1957, and received his B.Sc. (Summa Cum Laude) in 1961, and M.Sc. in 1962. He continued his Ph.D. studies at the Hebrew University of Jerusalem until 1965. His thesis on "Some Aspects of the Structure of Weak Interactions" was supervised by Prof.
Yuval Ne'eman Yuval Ne'eman ( he, יובל נאמן, 14 May 1925 – 26 April 2006) was an Israeli theoretical physicist, military scientist, and politician. He was Minister of Science and Development in the 1980s and early 1990s. He was the President o ...
.


Career

Horn joined the newly founded Tel Aviv University as an assistant in 1962. He became a lecturer in 1965, a senior lecturer in 1967 and an associate professor in 1968. He was promoted to full professor of Physics in 1972. In 1974 he became the incumbent of the Edouard and Francoise Jaupart Chair of Theoretical Physics of Particles and Fields, a position he held until 2007. Horn has supervised 43 graduate students at TAU and authored over 240 scientific publications. He retired as a professor emeritus in 2005, and continues to be an active researcher. Horn spent a significant part of his career holding visiting academic positions at other universities and research institutes, including: Postdoctoral Fellow at
Argonne National Lab Argonne National Laboratory is a science and engineering research national laboratory operated by UChicago Argonne LLC for the United States Department of Energy. The facility is located in Lemont, Illinois, outside of Chicago, and is the larg ...
, ILL, Research Fellow and three times Visiting Associate at
California Institute of Technology The California Institute of Technology (branded as Caltech or CIT)The university itself only spells its short form as "Caltech"; the institution considers other spellings such a"Cal Tech" and "CalTech" incorrect. The institute is also occasional ...
,
Pasadena Pasadena ( ) is a city in Los Angeles County, California, northeast of downtown Los Angeles. It is the most populous city and the primary cultural center of the San Gabriel Valley. Old Pasadena is the city's original commercial district. ...
, CA, Visitor at CERN in
Geneva , neighboring_municipalities= Carouge, Chêne-Bougeries, Cologny, Lancy, Grand-Saconnex, Pregny-Chambésy, Vernier, Veyrier , website = https://www.geneve.ch/ Geneva ( ; french: Genève ) frp, Genèva ; german: link=no, Genf ; it, Ginevr ...
, Visiting Professor at
Cornell University Cornell University is a private statutory land-grant research university based in Ithaca, New York. It is a member of the Ivy League. Founded in 1865 by Ezra Cornell and Andrew Dickson White, Cornell was founded with the intention to tea ...
, NY, Member of the
Institute for Advanced Study The Institute for Advanced Study (IAS), located in Princeton, New Jersey, in the United States, is an independent center for theoretical research and intellectual inquiry. It has served as the academic home of internationally preeminent schola ...
, Princeton, NJ, Visiting Professor at
SLAC SLAC National Accelerator Laboratory, originally named the Stanford Linear Accelerator Center, is a United States Department of Energy National Laboratory operated by Stanford University under the programmatic direction of the U.S. Departme ...
in Stanford University, CA, and Visiting Professor at Kyoto University, Japan. Beginning from 1980, Horn held official positions at Tel Aviv University, starting with tenure as Vice-Rector (1980-1983), a position he left for research at SLAC. After returning he was nominated Chairman of the Department of High Energy Physics (1984-1986), followed by tenures as Chairman of the School of Physics and Astronomy (1986-9), Dean of the Raymond and Beverly Sackler Faculty of Exact Sciences (1990-1995), and first Director of the Adams Super Center for Brain Studies (1993-2000). Horn has also held national and international professional positions. He was Chairman of the Israel Commission for
High Energy Physics Particle physics or high energy physics is the study of Elementary particle, fundamental particles and fundamental interaction, forces that constitute matter and radiation. The fundamental particles in the universe are classified in the Standa ...
(1983-2003), and, in this capacity, served as an Israeli observer of the council of CERN (1991-2003). He served as member of the Israel Council for Higher Education (1987-1991), member of the Executive Committee of the
European Physical Society The European Physical Society (EPS) is a non-profit organisation whose purpose is to promote physics and physicists in Europe through methods such as physics outreach. Formally established in 1968, its membership includes the national physical so ...
(1989-1992) and member of the European Strategy Forum on Research Infrastructures (2005-2017). He chaired the Israeli Committee of Research Infrastructures (2012-2016), issuing roadmaps for scientific RI in 2013 and 2016.


Research

Horn's research work focused on theory and phenomenology of High Energy Physics until 1990. He then shifted his interests to
Neural Computation Neural computation is the information processing performed by networks of neurons. Neural computation is affiliated with the philosophical tradition known as Computational theory of mind, also referred to as computationalism, which advances the th ...
and
Machine Learning Machine learning (ML) is a field of inquiry devoted to understanding and building methods that 'learn', that is, methods that leverage data to improve performance on some set of tasks. It is seen as a part of artificial intelligence. Machine ...
and, since 2005, he has also published in Bioinformatics. Together with Richard Dolen and Christoph Schmid he discovered the Finite Energy Sum Rules in 1967. It was a realization of the bootstrap approach to hadronic structure, and became known as the Dolen-Horn-Schmid Duality. Together with Richard Silver he investigated a model of coherent production of
pions In particle physics, a pion (or a pi meson, denoted with the Greek letter pi: ) is any of three subatomic particles: , , and . Each pion consists of a quark and an antiquark and is therefore a meson. Pions are the lightest mesons and, more gene ...
at high energy
hadron In particle physics, a hadron (; grc, ἁδρός, hadrós; "stout, thick") is a composite subatomic particle made of two or more quarks held together by the strong interaction. They are analogous to molecules that are held together by the e ...
collisions in 1971, and together with Jeffrey Mandula he undertook the investigation of
meson In particle physics, a meson ( or ) is a type of hadronic subatomic particle composed of an equal number of quarks and antiquarks, usually one of each, bound together by the strong interaction. Because mesons are composed of quark subparticles, ...
s with constituent
gluons A gluon ( ) is an elementary particle that acts as the exchange particle (or gauge boson) for the strong force between quarks. It is analogous to the exchange of photons in the electromagnetic force between two charged particles. Gluons bind q ...
in 1978. Moving to lattice gauge theories in 1979, he discovered, together with Shimon Yankielowic and Marvin Weinstein, a non-confining phase in Z(N) theories for large N. In 1981 he demonstrated the existence of finite matrix models with link gauge fields, nowadays known as quantum link models. In 1984 Horn and Weinstein developed the t-expansion methodology. Horn's contributions to neural modeling include a novel mechanism for memory maintenance via neuronal regulation in 1998, developed with Nir Levy and Eytan Ruppin and unsupervised learning of
natural languages In neuropsychology, linguistics, and philosophy of language, a natural language or ordinary language is any language that has evolved naturally in humans through use and repetition without conscious planning or premeditation. Natural languages ...
in 2005, a joint work with Zach Solan, Eytan Ruppin and Shimon Edelman, introducing novel
algorithm In mathematics and computer science, an algorithm () is a finite sequence of rigorous instructions, typically used to solve a class of specific problems or to perform a computation. Algorithms are used as specifications for performing ...
s for motif and grammar extraction from text. Horn has contributed to algorithms of clustering, an important topic in Machine Learning, by developing Support Vector Clustering (SVC) in 2001, together with Asa Ben Hur,
Hava Siegelmann Hava Siegelmann is a professor of computer science. Her academic position is in the school of Computer Science and the Program of Neuroscience and Behavior at the University of Massachusetts Amherst; she is the director of the school's Biologica ...
and Vladimir Vapnik. This was followed shortly thereafter by a joint work with Assaf Gottlieb on
Quantum Clustering Quantum Clustering (QC) is a class of data-clustering algorithms that use conceptual and mathematical tools from quantum mechanics. QC belongs to the family of density-based clustering algorithms, where clusters are defined by regions of higher ...
(QC). His contributions to Bioinformatics include motif descriptions of function and structure of
protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, res ...
s, as well as motif studies of genomic structures. Together with Erez Persi he studied compositional order of
proteomes The proteome is the entire set of proteins that is, or can be, expressed by a genome, cell, tissue, or organism at a certain time. It is the set of expressed proteins in a given type of cell or organism, at a given time, under defined conditions. ...
, and repeat instability of genomes, as evolution markers of organisms and of
cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...
(a joint work with Persi and others).


Honors

Horn is a Fellow of the American Physical Society (1985) and a Fellow of the Israel Physical Society (2018).


Publications


Selected articles

* R. Dolen, D. Horn and C. Schmid; Prediction of Regge-parameters of rho poles from low-energy pi-N scattering data Phys. Rev. Lett. 19 (1967) 402–407. Finite-Energy Sum Rules and Their Application to pi-N Charge Exchange Phys. Rev. 166 (1968) 1768–1781. * D. Horn and R. Silver: Coherent production of pions, Annals Phys. 66 (1971) 509-541 * T. Banks, D. Horn and H. Neuberger: Bosonization of the SU(N) Thirring Models, Nucl. Phys. B108, 119 (1976). * D. Horn and J. Mandula: Model of Mesons with Constituent Gluons, Phys. Rev. D17, 898 (1978). * D. Horn, M. Weinstein and S. Yankielowicz: Hamiltonian Approach to Z(N) Lattice Gauge Theories, Phys. Rev. D19, 3715 (1979). * D. Horn: Finite Matrix Models with Continuous Local Gauge Invariance, Phys. Lett. 100B, 149-151 (1981). * T. Banks, Y. Dothan and D. Horn: Geometric Fermions, Phys. Lett. 117B, 413 (1982). * D. Horn and M. Weinstein: The t expansion: A nonperturbative analytic tool for Hamiltonian systems. Phys. Rev. D 30, 1256-1270 (1984). * Ury Naftaly, Nathan Intrator and David Horn: Optimal Ensemble Averaging of Neural Networks. Network, Computation in Neural Systems, 8, 283-296 (1997). * David Horn, Nir Levy, Eytan Ruppin: Memory Maintenance via Neuronal Regulation, Neural Computation, 10, 1-18 (1998). * Asa Ben-Hur, David Horn, Hava Siegelmann and Vladimir Vapnik: Support Vector Clustering. Journal of Machine Learning Research 2, 125-137 (2001). * David Horn and Assaf Gottlieb: Algorithm for data clustering in pattern recognition problems based on quantum mechanics, Phys. Rev. Lett. 88 (2002) 18702 * Zach Solan, David Horn, Eytan Ruppin and Shimon Edelman: Unsupervised learning of natural languages, Proc. Natl. Acad. Sc. 102 (2005) 11629–11634. * Vered Kunik, Yasmine Meroz, Zach Solan, Ben Sandbank, Uri Weingart, Eytan Ruppin and David Horn: Functional representation of enzymes by specific peptides. PLOS Computational Biology 2007, 3(8):e167. * Benny Chor, David Horn, Yaron Levy, Nick Goldman and Tim Massingham: Genomic DNA k-mer spectra: models and modalities. Genome Biology 2009, 10(10):R108 * Erez Persi and David Horn. Systematic Analysis of Compositional Order of Proteins Reveals New Characteristics of Biological Functions and a Universal Correlate of Macroevolution. PLoS Comput Biol 9 (2013): e1003346. * David Horn. Taxa counting using Specific Peptides of Aminoacyl tRNA Synthetases Encyclopedia of Metagenomics, Springer, 2013. * Sagi Shporer, Benny Chor, Saharon Rosset, David Horn. Inversion symmetry of DNA k-mer counts: validity and deviations. BMC Genomics 2016, 17:696 * Erez Persi, Davide Prandi, Yuri I. Wolf, Yair Pozniak, Christopher Barbieri, Paola Gasperini, Himisha Beltran, Bishoy M. Faltas, Mark A. Rubin, Tamar Geiger, Eugene V. Koonin, Francesca Demichelis, David Horn. Proteomic and Genomic Signatures of Repeat Instability in Cancer and Adjacent Normal Tissues. PNAS 116, 34, 2019 - 08790


Book

* David Horn and Fredrick Zachariasen: Hadron Physics at Very High Energies. Benjamin 1973.


Patents

* Method and Apparatus for Quantum Clustering. USA Patent No. 7,653,646 B2. * Method for discovering relationships in data by dynamic quantum clustering USA Patent No 8874412 and USA Patent No. 9,646,074.


Personal life

Horn was married to Nira Fuss since 1963 until her death in 2019. He is a father of three, Yuval, Tamar, and Oded, and grandfather of nine. He lives in
Tel Aviv Tel Aviv-Yafo ( he, תֵּל־אָבִיב-יָפוֹ, translit=Tēl-ʾĀvīv-Yāfō ; ar, تَلّ أَبِيب – يَافَا, translit=Tall ʾAbīb-Yāfā, links=no), often referred to as just Tel Aviv, is the most populous city in the ...
, Israel.


References


External links


David Horn
Tel Aviv university *
Challenges of Science and Technology in the 21st Century - Interdisciplinary TAU Symposium in honor of David Horn on his 80th birthday
YouTube YouTube is a global online video sharing and social media platform headquartered in San Bruno, California. It was launched on February 14, 2005, by Steve Chen, Chad Hurley, and Jawed Karim. It is owned by Google, and is the second mo ...
{{DEFAULTSORT:Horn, David Israeli physicists Artificial intelligence researchers Living people Academic staff of Tel Aviv University Technion – Israel Institute of Technology alumni 1937 births Machine learning researchers Israeli bioinformaticians Particle physicists Hebrew University of Jerusalem alumni Fellows of the American Physical Society People associated with CERN