David Blech
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David Abraham Blech (born November 25, 1955) is an American businessman, investor, and venture capitalist. He is one of the financial pioneers of the
biotech Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used b ...
industry and was once known as the "King of Biotech".


Early life and education

Blech grew up in Brooklyn, New York. Blech graduated from Baruch College and earned a Master's in Music Education at the Teacher's College of Columbia University.


Early career

Since 1980, Mr. Blech has been a founder of companies and venture capital investor in the biotechnology sector. His initial venture investment, Genetic Systems Corporation, which he helped found with his father and his brother Isaac Blech, was built around promising scientists, including the high profile microbiologist Robert Nowinski. It developed the first inexpensive and accurate test to diagnosis sexually-transmitted diseases using
monoclonal antibodies A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell Lineage made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to a unique parent cell. Monoclonal antibodies ca ...
, allowing tens of thousands of babies to be born to women who otherwise would have become sterile from
pelvic inflammatory disease Pelvic inflammatory disease, also known as pelvic inflammatory disorder (PID), is an infection of the upper part of the female reproductive system, namely the uterus, fallopian tubes, and ovaries, and inside of the pelvis. Often, there may be no ...
. The company was sold to
Bristol Myers The Bristol Myers Squibb Company (BMS) is an American multinational pharmaceutical company. Headquartered in New York City, BMS is one of the world's largest pharmaceutical companies and consistently ranks on the ''Fortune'' 500 list of the lar ...
in 1986 for $294 million (3%) of Bristol Myers stock. In 1989, Blech co-founded
Icos Corporation Icos Corporation (trademark ICOS) was an American biotechnology company and the largest biotechnology company in the U.S. state of Washington, before it was sold to Eli Lilly and Company in 2007. It was founded in 1989 by David Blech, Isaac B ...
with Nowinski and George B. Rathmann, receiving the largest start up financing in biotech history at $33 million. Icos discovered the drug Cialis, which was acquired by Eli Lilly in 2003 for over $2.6 billion. The Blechs also co-founded Celgene Corporation in 1986, which was a unit of the
Celanese Corporation Celanese Corporation, formerly known as Hoechst Celanese, is an American technology and specialty materials company headquartered in Irving, Texas. A Fortune 500 corporation, the company is the world’s leading producer of acetic acid, produc ...
, and was spun off as an independent company following the merger of
Celanese Corporation Celanese Corporation, formerly known as Hoechst Celanese, is an American technology and specialty materials company headquartered in Irving, Texas. A Fortune 500 corporation, the company is the world’s leading producer of acetic acid, produc ...
with American Hoechst Corporation. Celgene introduced two major cancer drugs, and has a current value of over $35 billion, making it the 5th largest biotech company in the world. Other companies he helped found include
DNA Plant Technology DNA Plant Technology was an early pioneer in applying transgenic biotechnology to problems in agriculture. The company was founded in Cinnamonson, New Jersey, and moved to California in 1994. Some of the plants and products they developed include ...
, Neurogen Corporation, Incyte Pharmaceuticals, Alexion Pharmaceuticals,
ARIAD Pharmaceuticals ARIAD Pharmaceuticals, Inc. was an American oncology company, now part of Takeda Oncology, which was founded in 1991 by Harvey J. Berger, M.D. and headquartered in Cambridge, Massachusetts. ARIAD engaged in the discovery, development, and commer ...
,
Neurocrine Biosciences Neurocrine Biosciences, Inc. is an American biopharmaceutical company founded in 1992. The company is headquartered in San Diego, California, and led by CEO Kevin Gorman. Neurocrine develops treatments for neurological and endocrine-related diseas ...
,
Cytosorbents CytoSorbents Corporation is a publicly traded company (NasdaqCM: CTSO) located in Monmouth Junction, New Jersey. CytoSorbents sells a cytokine adsorbing column ("CytoSorb" which received CE mark approval in 2011) — a blood purification techn ...
Inc, and Intellect Neurosciences. He was also instrumental in the turnaround of Liposome Technology Inc. and Biotech General Corporation. In 1990, Mr. Blech founded D. Blech & Company, which, until it ceased doing business in September 1994, was a registered broker-dealer involved in underwriting biotechnology issues. At his peak in 1992, Blech's wealth was estimated at almost $300 million, briefly making him a member of the Forbes 400. Falling deep into debt, D. Blech & Co was in violation of
net capital rule The uniform net capital rule is a rule created by the U.S. Securities and Exchange Commission ("SEC") in 1975 to regulate directly the ability of broker-dealers to meet their financial obligations to customers and other creditors. Broker-dealers a ...
s and ceased operations on September 22, 1994, a day that came to be known as "Blech Thursday" in the biotech industry. Blech came under investigation by the SEC for securities fraud. During the investigation Lloyd Schwed, a Florida-based attorney representing a group of former brokers, attempted to blackmail Blech by promising to withhold tapes subpoenaed during the investigation. Blech became an informant in exchange for leniency. He pleaded guilty to two counts of criminal fraud and was sentenced to a five-year term of probation. A documentary film titled '' The Blech Effect'' was released in 2020 documenting his rise and fall in the industry.


Personal

Blech says he is
bipolar Bipolar may refer to: Astronomy * Bipolar nebula, a distinctive nebular formation * Bipolar outflow, two continuous flows of gas from the poles of a star Mathematics * Bipolar coordinates, a two-dimensional orthogonal coordinate system * Bipolar ...
, has a
gambling addiction Problem gambling or ludomania is repetitive gambling behavior despite harm and negative consequences. Problem gambling may be diagnosed as a mental disorder according to ''DSM-5'' if certain diagnostic criteria are met. Pathological gambling is ...
and is a member of Gamblers Anonymous.


References

{{DEFAULTSORT:Blech, David 1955 births American investors People from Brooklyn Teachers College, Columbia University alumni Living people Baruch College alumni American businesspeople convicted of crimes