David P. Ballou is a professor emeritus of biological chemistry at the

University of Michigan , mottoeng = "Arts, Knowledge, Truth" , former_names = Catholepistemiad, or University of Michigania (1817–1821) , budget = $10.3 billion (2021) , endowment = $17 billion (2021)As o ...

Medical School in the

United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territorie ...

. He is best known for his development of rapid-reaction techniques, including

stopped flow Stopped-flow is an experimental technique for studying chemical reactions with a half time of the order of 1 ms, introduced by Britton Chance and extended by Quentin Gibson (Other techniques, such as the temperature-jump method, are available for ...

and rapid freeze-quench EPR methods, as tools to study the mechanisms of enzymes containing flavin,

iron Iron () is a chemical element with symbol Fe (from la, ferrum) and atomic number 26. It is a metal that belongs to the first transition series and group 8 of the periodic table. It is, by mass, the most common element on Earth, right in f ...

cobalamin Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. It is one of eight B vitamins. It is required by animals, which use it as a cofactor in DNA synthesis, in both fatty acid and amino acid metabolism. It ...

, or

pyridoxal phosphate Pyridoxal phosphate (PLP, pyridoxal 5'-phosphate, P5P), the active form of vitamin B6, is a coenzyme in a variety of enzymatic reactions. The International Union of Biochemistry and Molecular Biology has catalogued more than 140 PLP-dependent ac ...

cofactors Cofactor may also refer to: * Cofactor (biochemistry), a substance that needs to be present in addition to an enzyme for a certain reaction to be catalysed * A domain parameter in elliptic curve cryptography, defined as the ratio between the order ...

. Many of these studies were performed in collaboration with other scientists, most often with colleagues at Michigan.

Biography

David Ballou grew up in

Connecticut Connecticut () is the southernmost state in the New England region of the Northeastern United States. It is bordered by Rhode Island to the east, Massachusetts to the north, New York to the west, and Long Island Sound to the south. Its cap ...

. He received a B.S. in chemistry from

Antioch College Antioch College is a private liberal arts college in Yellow Springs, Ohio. Founded in 1850 by the Christian Connection, the college began operating in 1852 as a non-sectarian institution; politician and education reformer Horace Mann was its f ...

in 1965. In 1971, he received a Ph.D. from the

under the supervision of Graham Palmer. From 1971-1972, he was a postdoctoral fellow with

Vincent Massey Charles Vincent Massey (February 20, 1887December 30, 1967) was a Canadian lawyer and diplomat who served as Governor General of Canada, the 18th since Confederation. Massey was the first governor general of Canada who was born in Canada after ...

and

Minor J. Coon Minor Jesser Coon (July 29, 1921 – September 5, 2018) was an American biochemist and Victor V Vaughan Distinguished University Professor Emeritus at the University of Michigan, Ann Arbor. He is best known for his research on cytochrome P-450 an ...

at the

. He has been a faculty member in the Department of Biological Chemistry at the

Medical School since 1972. In 2007, Ballou became a Fellow of the

American Association for the Advancement of Science The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific respons ...

in recognition of his discovery of enzyme intermediates that are involved in biological oxidation reactions. His most cited paper, l, "Oxidative Protein Folding Is Driven by the Electron Transport System", has been cited 311 times according to Google Scholar, and he has contributed to 25 papers having more than 0100 citations each.

Books

*''Fundamental Laboratory Approaches for Biochemistry and Biotechnology (2nd Ed)'' (2009) by Alexander J. Ninfa, David P. Ballou, and Marilee Benore. Published by Wiley ().

References

External links

Ballou ''et al'' publications on Pubmed

David Ballou's page at the University of Michigan Medical School
archived from th
original
{{DEFAULTSORT:Ballou, David P. Living people American biochemists Fellows of the American Association for the Advancement of Science University of Michigan College of Literature, Science, and the Arts alumni University of Michigan faculty Year of birth missing (living people)