Darlene may refer to:
*
Darlene (given name)
The first name Darlene is derived from the Old English ''darel-ene'', meaning "little dear one".
Notable people
* Darlene (formerly known as Darlene Pekul), American artist and calligrapher
*Darlene Conley, American actress
* Darlene de Souza, Bra ...
, people with the given name Darlene
*
Darlene (artist), American artist formerly known as Darlene Pekul
*
"Darlene" (Led Zeppelin song)
*
"Darlene" (T. Graham Brown song)
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