D-aspartate oxidase In enzymology, a D-aspartate oxidase () is an enzyme that catalyzes the chemical reaction :D-aspartate + H2O + O2 \rightleftharpoons oxaloacetate + NH3 + H2O2 The 3 substrates of this enzyme are D-aspartate, H2O, and O2, whereas its 3 pro ...

is an

enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...

that is encoded by the ''DDO''

gene In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...

. The protein encoded by this gene is a peroxisomal flavoprotein that catalyzes the oxidative deamination of D-aspartate and ''N''-methyl D-aspartate.

Flavin adenine dinucleotide Flavin may refer to: Placename * Flavin, Aveyron, a commune in southern France Surname * Adrian Flavin (born 1979), a professional rugby player * Christopher Flavin, president of the Worldwatch Institute * Dan Flavin (1933–1996), a minimalis ...

or 6-hydroxyflavin adenine dinucleotide can serve as the cofactor in this reaction. Two (or four, according to ) transcript variants encoding different isoforms have been found for this gene.

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Further reading