DCN1-like protein 1 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
that in humans is encoded by the ''DCUN1D1''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
DCUN1D1 is amplified in several cancer types, including squamous cell cancers, and may act as an oncogenic driver in cancer cells.
Interactions
DCUN1D1 has been shown to
interact
Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human rights of children with intersex traits. The organizati ...
with:
*
CAND1
Cullin-associated NEDD8-dissociated protein 1 is a protein that in humans is encoded by the ''CAND1'' gene.
Interactions
CAND1 has been shown to interact with:
* CUL1,
* CUL2,
* CUL3,
* CUL4A,
* CUL4B,
* DCUN1D1, and
* RBX1
RING-box pro ...
,
*
CUL1,
[
* ]CUL2
Cullin-2 is a protein that in humans is encoded by the ''CUL2'' gene.
Interactions
CUL2 has been shown to interact with:
* CAND1,
* DCUN1D1,
* RBX1,
* SAP130,
* TCEB2 and
* Von Hippel-Lindau tumor suppressor
The term ''von'' () is us ...
,[
* ]CUL3
Cullin 3 is a protein that in humans is encoded by the ''CUL3'' gene.
Cullin 3 protein belongs to the family of cullins which in mammals contains eight proteins (Cullin 1, Cullin 2, Cullin 3, Cullin 4A, Cullin 4B, Cullin 5, Cullin 7 and Cullin 9) ...
[ and
* ]RBX1
RING-box protein 1 is a protein that in humans is encoded by the ''RBX1'' gene.
Function
This gene encodes an evolutionarily conserved protein that interacts with cullins. The protein plays a unique role in the ubiquitination reaction by hetero ...
.[
]
References
Further reading
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