DCG-IV is a research drug which acts as a group-selective agonist for the group II metabotropic glutamate receptors (
mGluR2/ 3).
It has potent
neuroprotective
Neuroprotection refers to the relative preservation of neuronal structure and/or function. In the case of an ongoing insult (a neurodegenerative insult) the relative preservation of neuronal integrity implies a reduction in the rate of neuronal los ...
and
anticonvulsant effects in animal studies,
as well as showing anti-
Parkinsonian
Parkinsonism is a clinical syndrome characterized by tremor, bradykinesia (slowed movements), rigidity, and postural instability. These are the four motor symptoms found in Parkinson's disease (PD), after which it is named, dementia with Lewy b ...
effects,
but also impairs the formation of memories.
References
Anticonvulsants
Amino acids
Tricarboxylic acids
Cyclopropanes
MGlu2 receptor agonists
MGlu3 receptor agonists
{{anticonvulsant-stub