Dumbala Srinivasa Reddy (born 1971) is currently Director CSIR-IICT Indian Institute of Chemical Technology Hyderabad India (June 2022), he has additional charge of CSIR-IIIM CSIR-Institute of Integrative Medicine at Jammu and CSIR-CDRI CSIR-Drug Research Institute at Lucknow, India. Dsr 4

He is Indian organic and medicinal chemist and was a senior scientist at

National Chemical Laboratory The National Chemical Laboratory (NCL) is an Indian government laboratory based in Pune, in western India. Popularly known as NCL, a constituent member of the CSIR India, Council of Scientific & Industrial Research (CSIR) India, it was estab ...

. He is known for the application of ''Silicon-switch approach'', a management protocol for treating diseases affecting the central nervous system in his researches and is a recipient of the Bronze Medal of the

Chemical Research Society of India Chemical Research Society of India (CRSI) is an India based scientific society A learned society (; also learned academy, scholarly society, or academic association) is an organization that exists to promote an academic discipline, professio ...

NASI Nasi may refer to: Food Dishes Nasi Goreng is an Indonesian and Malay word for ''cooked rice'', featured in many Southeast Asian dishes *Nasi goreng, a popular rice dish often simply called ''nasi'' *Other Southeast Asian ''nasi'' dishes: **Nasi ...

Reliance Industries Reliance Industries Limited is an Indian multinational conglomerate company, headquartered in Mumbai. It has diverse businesses including energy, petrochemicals, natural gas, retail, telecommunications, mass media, and textiles. Reliance is ...

Platinum Jubilee Award and the Drug Research Excellence Award of the

Central Drug Research Institute The Central Drug Research Institute is a multidisciplinary research laboratory in Lucknow, India, employing scientific personnel from various areas of biomedical sciences. Prof. Tapas Kumar Kundu, a molecular biologist, academician and recipien ...

. The

Council of Scientific and Industrial Research The Council of Scientific and Industrial Research (IAST: ''vaigyanik tathā audyogik anusandhāna pariṣada''), abbreviated as CSIR, was established by the Government of India in September 1942 as an autonomous body that has emerged as the l ...

, the apex agency of the Government of India for scientific research, awarded him the

Shanti Swarup Bhatnagar Prize for Science and Technology The Shanti Swarup Bhatnagar Prize for Science and Technology (SSB) is a science award in India given annually by the Council of Scientific and Industrial Research (CSIR) for notable and outstanding research, Applied science, applied or Fundamenta ...

, one of the highest Indian science awards, in 2015, for his contributions to chemical sciences.

Biography

He did BSC from SP College Secunderabad, D. Srinivasa Reddy graduated in chemistry in 1991 from

Osmania University Osmania University is a collegiate public state university located in Hyderabad, Telangana, India. Mir Osman Ali Khan, the 7th Nizam of Hyderabad in 1918 , He released a farman to establish OSMANIA UNIVERSITY on the day of 28 August 1918. It ...

and completed his master's degree from the same institution Nizams college in 1993. He joined IICT as project assistant, cleared CSIR-NET and enrolled for doctorate, under the guidance of

Goverdhan Mehta Goverdhan Mehta FNA, FASc, FTWAS, FRS, FRSC (born 26 June 1943) is an Indian researcher and scientist. Career Mehta received his BSc and MSc from the BITS Pilani and PhD from Pune University. His post-doctoral research was at the Michig ...

, a noted chemist and former vice chancellor of

University of Hyderabad The University of Hyderabad (IAST: ''Hydarāvād visvavidyālayamu'') is a top ranking public central research university located in Hyderabad, Telangana, India. Founded in 1974, this mostly residential campus has more than 5,000 students a ...

, he moved to

Indian Institute of Science The Indian Institute of Science (IISc) is a public, deemed, research university for higher education and research in science, engineering, design, and management. It is located in Bengaluru, in the Indian state of Karnataka. The institute wa ...

when Mehta took up the position as the head of the department of organic chemistry at IISc. His PhD came from Hyderabad University in 2000, During this period, he met Vidya Ramadas who was also pursuing her PhD in the same research group and later married her. Dr Reddy proceeded to the US where he did his post-doctoral work at the laboratories of Sergey A. Kozmin of the

University of Chicago The University of Chicago (UChicago, Chicago, U of C, or UChi) is a private research university in Chicago, Illinois. Its main campus is located in Chicago's Hyde Park neighborhood. The University of Chicago is consistently ranked among the b ...

and Jeffrey Aubé of

University of Kansas The University of Kansas (KU) is a public research university with its main campus in Lawrence, Kansas, United States, and several satellite campuses, research and educational centers, medical centers, and classes across the state of Kansas. Tw ...

during 2001–03. He started his career in 2003 as a principal scientist at Dr. Reddy’s Laboratories and became a research investigator in 2006 but a year later, he moved to Advinus Therapeutics as the group leader of their ''Discovery Chemistry'' research wing. In 2010, he was promoted as the section head; soon after, he left for

where he worked as a senior scientist. He is currently Director CSIR-IICT Hyderabad India ">ref name="CSIR-IICT"/> he has additional charge of CSIR-IIIM at Jammu and CSIR-CDRI at Lucknow, India. He is currently 10th director at IICT.

Selected patents

1. Enantiospecific synthesis of pheromones, D. Srinivasa Reddy, Remya Ramesh, WO2016181413A4; US10221122B2. 2. Process for the synthesis of ivacaftor and related compounds, D. Srinivasa Reddy, N. Vasudevan, GorakhJachak, WO2016181414A1; US20180127373A1. 3. Tricyclic compounds and process for preparation thereof, D. Srinivasa Reddy, Kishor L. Handore, WO2016013032A1; US9950983B2. 4. Synthesis of tricyclic compounds and uses thereof, D. Srinivasa Reddy, K. Kashinath, PrakashJadhav, WO2015121876A1. 5. Novel N-heterocyclic carbene compounds, their preparation and use,D. Srinivasa Reddy, Revannath L. Sutar, Vinod Kumar, Rahul D. Shingare, WO2015102020A1. 6. Silicon based fungicides and process for producing the same, D. Srinivasa Reddy, GorakhJachak, Remya Ramesh, SantoshTupe, MukundDeshpande, US10053472B2, WO2015102025A1; EP3089985B1. 7. Novel indazole compounds and a process for the preparation thereof, D. Srinivasa Reddy, Chaitanya Saxena, K. Kashinath,WO2015015519A1; US9737510B2; DK3027605T3; EP3027605B1; JP6474808B2; KR20160053916A; CN106103427A; CA2919953A1; DK3027605T3; ES2656475T3. 8. Novel pyrrole compounds with silicon incorporation, D. Srinivasa Reddy, Vasudevan Natarajan, Sachin B. Wagh, Remya Ramesh, US9657037B2; WO2014195970A4. 9. Novel pyrazole compounds with silicon incorporation, D. Srinivasa Reddy, Remya Ramesh, Rahul D. Shingare, WO2014181357A1. 10. Insect repellents, D. Srinivasa Reddy, Kishor L. Handore, B. Seetharam Singh, AvalokiteswarSen, PushpaPawar, Mary Joseph, WO2014170915A1. 11. Anticancer compounds and process for the preparation thereof, D. Srinivasa Reddy, Kishor L. Handore, US9845302B2; WO2014128723A3. 12. Antitubercular compounds and process for the preparation thereof, D. Srinivasa Reddy, Remya Ramesh, WO2014128724A1. 13. Enantioselective process for the preparation of enantiomers of sex pheromones, D. Srinivasa Reddy, US9598346B2; WO2014115172A1. 14. A process for the preparation of aminoacrylic acid derivatives, D. Srinivasa Reddy, K. Kashinath, P. Siva Swaroop, US9193674B2; WO2013054366A8; EP2766340B1. 15. Sila analogs of oxazolidinone derivatives and synthesis thereof D. Srinivasa Reddy, B. Seetharam Singh, Remya Ramesh, WO2013054275A1; EP2766373B1; JP6162704B2; US9233989B2. 16. Glycoside derivatives and uses thereof, B. G. Raymond, Bock Mark G, D. Srinivasa Reddy, Hajare Atul K, Vyavahare Vinod, Bhosale Sandeep B, Kurhade Suresh E, Salunkhe Videsh, Shaikh Nadim S, Bhuniya Debnath, Palle P. Venkata, FengLili,LiangJessica,US8163704B2/US9895389B2; EP2491029B1; JP5384744B2; KR101465308B1; CN102656165B; CA2777812C;DK2491029T3; ES2564191T3; WO2011048112A1; TWI594765B 17. Glycoside derivative and uses thereof, B. G. Raymond, Bock Mark G, Bhuniya Debnath, Datrange Laxmikant, Kurhade Suresh E, Palle P. Venkata, D. SrinivasaReddy EP2491050; CA2778384A1; US8394772B2; KR20120087950A; CN102510867A; WO2011048148A3. 18. Glucoside derivatives and uses thereof as sglt inhibitors, Palle P. Venkata, Bhuniya Debnath, D.SrinivasaReddy, KurhadeSureshE, US20110269700A1; JP2012502953A; KR20110060935A; CA2737831A1; CN102159206A; WO2010031820A1; AU2009294613A1 19. Glycoside derivatives and uses thereof, Palle P. Venkata, D. Srinivasa Reddy, Kurhade SureshE, Bhuniya Debnath, US20110230403A1; WO2010031813A1; JP2012502950A; KR20110055740A; CN102159561A;CA2737830A1 20. Fused heterocyclic C-glycosides for the treatment of diabetes, B. G. Raymond, Bhosale Sandeep B, Bhuniya Debnath, Hajare Atul K, Mengawade Tanaji, Mukhopadhyay P, Palle P. Venkata, D. Srinivasa Reddy, WO2010128152A1 21. Novel heterocyclic compounds as lasy activators D. Srinivasa Reddy, Padmalayam Indira, Bhuniya Debnath, Pillarisetti Sivaram, Chakrabarti Ranjan, WO2008036967A3 22. Methods and compositions for the treatment of inflammation, obesity and related metabolic disorders, Padmalayam Indira, Bhuniya Debnath, D. Srinivasa Reddy, Khanna Ish, Saxena Uday, Pillarisetti Sivaram, WO2008036966A3.

Research

Reddy's research have been focused on total organic synthesis of molecules with a view to their applications in agricultural and medicinal uses. He is credited with the total synthesis of over 20

agro-chemicals An agrochemical or agrichemical, a contraction of ''agricultural chemical'', is a chemical product used in industrial agriculture. Agrichemical refers to biocides ( pesticides including insecticides, herbicides, fungicides and nematicides) an ...

which includes a

mealy bug In the theory of computation, a Mealy machine is a finite-state machine whose output values are determined both by its current state and the current inputs. This is in contrast to a Moore machine, whose output values are determined solely by its cu ...

-attracting

sex pheromone Sex pheromones are pheromones released by an organism to attract an individual of the same species, encourage them to mate with them, or perform some other function closely related with sexual reproduction. Sex pheromones specifically focus on ind ...

that has reported use in crop protection. He has also developed several other products that has potential uses as cell-adhesion inhibitors, antibacterial, anti-inflammatory as well as anti-cancer agents and as insect repellents. He employs the ''Silicon-switch approach'' for developing drug strategies for diseases affecting the central nervous system and his work has assisted in the drug discovery for the treatment of some infectious diseases as well as

diabetes Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased ap ...

. His researches have been documented by way of a number of peer-reviewed articles;

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines. Released in beta in November 2004, the Google Scholar index includes p ...

, an online article repository of scientific articles, has listed 123 of them respectively. He has also applied for 30 patents based on his researches.

Awards and honours

Reddy received the Award for Excellence in Drug Research of the

in 2013 and the Scientist of the Year Award of the National Chemical Laboratory the same year. He received three awards in 2015, starting with the

Platinum Jubilee Award, followed by the Bronze Medal of the

. The Council of Scientific and Industrial Research awarded him the

Shanti Swarup Bhatnagar Prize The Shanti Swarup Bhatnagar Prize for Science and Technology (SSB) is a science award in India given annually by the Council of Scientific and Industrial Research (CSIR) for notable and outstanding research, Applied science, applied or Fundamenta ...

, one of the highest Indian science awards, also in 2015.

References

External links