Constantin von Monakow
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Constantin von Monakow (4 November 1853 – 19 October 1930) was a Russian-Swiss neuropathologist who was a native of Bobretsovo in the
Vologda Governorate Vologda Governorate (russian: link=no, Вологодская губерния, ''Vologodskaya guberniya'', ''Government of Vologda'') was an administrative division (a '' guberniya'') of the Russian Empire and the Russian SFSR, which existed fr ...
. He studied at the
University of Zurich The University of Zürich (UZH, german: Universität Zürich) is a public research university located in the city of Zürich, Switzerland. It is the largest university in Switzerland, with its 28,000 enrolled students. It was founded in 1833 f ...
while working as an assistant at the
Burghölzli The ''Psychiatrische Universitätsklinik Zürich'' (Psychiatric University Hospital Zürich) is a psychiatric hospital in Switzerland. As a research hospital, it is associated with the University of Zürich. It is also called Burghölzli, after ...
Institute under the directorship of Eduard Hitzig (1839-1907). After graduation, he was an assistant at St. Pirminsberg, where he performed scientific investigations of cerebral
anatomy Anatomy () is the branch of biology concerned with the study of the structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old science, having i ...
. In 1885 he returned to Zurich, where he later became director of the brain anatomy institute. In 1917 he founded the journal ''Schweizer Archiv für Neurologie und Psychiatrie'' (Swiss Archives of Neurology and Psychiatry), and was its editor-in-chief until his death. He died in Zurich in 1930.


Neuropathological research

Monakow made numerous contributions in his analysis of the sensory and
motor An engine or motor is a machine designed to convert one or more forms of energy into mechanical energy. Available energy sources include potential energy (e.g. energy of the Earth's gravitational field as exploited in hydroelectric power g ...
pathways of the brain. He was interested in the functional relationships amongst the different regions of the brain, and conceptualized that in faculties such as
intellect In the study of the human mind, intellect refers to, describes, and identifies the ability of the human mind to reach correct conclusions about what is true and what is false in reality; and how to solve problems. Derived from the Ancient Gre ...
, coordination was needed among its many diverse parts. From his brain research, he introduced the terms "chronogenic localization" and " diaschisis". In 1910 Monakow coined the term "diaschisis" to describe how an injury to the brain can create behavioral deficiencies that may be followed by eventual recovery. The word is derived from Greek, meaning "shocked throughout". He believed the brain to exist as a delicate balance between its different components, and if a component became disturbed through injury it could affect other parts of the brain not seemingly associated with the site of injury. Therefore, if the damage wasn't too severe, functional behaviour would recover once the period of diaschisis wore off. His name is lent to "Monakow's nucleus" ( lateral cuneate nucleus) and to the "bundle of Monakow" ( rubrospinal fasciculus). In addition, "Monakow's syndrome" bears his name, defined as contralateral
hemiplegia Hemiparesis, or unilateral paresis, is weakness of one entire side of the body ('' hemi-'' means "half"). Hemiplegia is, in its most severe form, complete paralysis of half of the body. Hemiparesis and hemiplegia can be caused by different med ...
, hemi
anaesthesia Anesthesia is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes. It may include some or all of analgesia (relief from or prevention of pain), paralysis (muscle relaxation), a ...
and homonomous hemianopsia due to occlusion of the anterior choroidal artery. He was responsible for identifying the
arcuate fasciculus The arcuate fasciculus (AF) is a bundle of axons that generally connects the Broca's area and the Wernicke's area in the brain. It is an association fiber tract connecting caudal temporal cortex and inferior frontal lobe. ''Fasciculus arcuatus' ...
as the fibre tract that connected the Broca's and Wernicke's speech areas. This anatomical link (which is now questioned)Catani M, Mesulam M. (2008). The arcuate fasciculus and the disconnection theme in language and aphasia: history and current state. Cortex. 44(8):953-61. “soon became a dogma in neurology and still today provides the backbone of anatomical models of language.” He is mentioned in ''Anti Oedipus'', the first volume of Deleuze and Guattari's ''Capitalism and Schizophrenia'', because of his work with Mourgue which they claim posits 'the introduction of desire into neurology.'


Selected writings

* ''Beitrag zur Localisation von Hirnrindentumoren'', (Thesis/dissertation) (1881) – On localization of cerebral cortex tumors. * ''Pathologie du cerveau'', in German as ''Gehirnpathologie'' (1897) – Brain pathology. * ''Über Lokalisation der Hirnfunktion'' (1910) – On localization of brain function. * ''La localisation de l'encéphale et la dégradation fonctionelle par des lésions circonscrites du cortex cérébral'', in German as ''Die Lokalisation im Grosshirn und Abbau der Funktion durch kortikale Herde'' (1914) – Localization in the cortex and the reduction of cortical function. * ''Gefuhl, Gesittung und Gehirn'', (1916); translated and published in English as "The emotions, morality and the brain"; Washington, Nervous and Mental Disease Pub. Co., 1925.WorldCat Search
published works by Monachow
* ''Psychiatrie und Biologie'', (1919) – Psychology and
biology Biology is the scientific study of life. It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. For instance, all organisms are made up of cells that process hereditary ...
. * ''Schizophrenie und Plexus chorioidei'' (with Kitabayashi), (1919) -
Schizophrenia Schizophrenia is a mental disorder characterized by continuous or relapsing episodes of psychosis. Major symptoms include hallucinations (typically hearing voices), delusions, and disorganized thinking. Other symptoms include social w ...
and the
choroid plexus The choroid plexus, or plica choroidea, is a plexus of cells that arises from the tela choroidea in each of the ventricles of the brain. Regions of the choroid plexus produce and secrete most of the cerebrospinal fluid (CSF) of the central nerv ...
.


References


Vologda Oblast Government, Biography


External links



* ttp://members.tripod.com/~ThJuland/neurons.html Monakow and Diaschisis {{DEFAULTSORT:Monakow, Constantin von Swiss neurologists 1853 births 1930 deaths People associated with the University of Zurich History of psychiatry